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Scientists have found a way of mapping out human DNA.
DNA changes throughout a person’s life can significantly increase their susceptibility to heart conditions and other age-related diseases, says a research led by an Indian-origin scientist.
Such alterations — known as somatic mutations — can impact the way blood stem cells work and are associated with blood cancers and other conditions, said scientists from the Universities of Edinburgh and Glasgow.
These somatic mutations and the associated diseases they cause may accelerate a person’s biological age — how old their body appears — faster than their chronological age.
“Previously, somatic mutations have largely been studied in cancer. Our findings suggest they play a role in other diseases, which will change the way we study disease risk,” said Dr Tamir Chandra, Group Leader at the University of Edinburgh’s MRC Human Genetics Unit.
The study, published in the journal Current Biology, examined these changes and their potential effects in more than 1,000 older people from the Lothian Birth Cohorts (LBCs), born in 1921 and 1936.

Cancer Ribbon. Pixabay

The LBCs are a group of people – now in their 80s and 90s – who sat intelligence tests as 11-year olds. They are some of the most-intensively studied research participants in the world.
Scientists studied people where the biological and chronological age was separated by a large gap.
They found the participants with somatic mutations – around six per cent – had a biological age almost four years older than those with no alterations.
Experts say they will now explore the link between these DNA changes and biological ageing acceleration. (IANS)

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Named SEE-1, the module is intended to host films, etc in the low orbit, micro-gravity environment.

S.E.E. has unveiled plans to build a space station module that contains a sports and entertainment arena as well as a content studio by December 2024, reports variety.com.

Named SEE-1, the module is intended to host films, television, music and sports events as well as artists, producers and creatives who want to make content in the low orbit, micro-gravity environment. The facilities will enable development, production, recording, broadcasting and livestreaming of content.

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S.E.E. intend to produce its own content and events in the module as well as making it available to third-parties. Axiom Space, who in January 2022 won NASA's approval to build a commercial component of the International Space Station (ISS), will undertake the construction of SEE-1. The module will dock on Axiom's commercial arm, named Axiom Station, which will also host other commercial ventures, including space tourism.

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IANS

As the economy continues to recover from the prolonged pandemic.

By Rohit Vaid
The Centre might bestow infrastructure as well as industry status to new sectors to boost several pandemic hit industries in the upcoming Union Budget. Industry insiders said that several sectors and sub-industries such as hospitality, automobile retail, specific diganotics facilities and companies engaged in installation of EV charging stations amongst others might get the status.
The infra tag will enable these sectors to avail tax breaks, incentives and credit on lower interest rates. "Sectors which are in greenfield or which would need capex augmentation to help them overcome the pandemic can be looked from the lens of an infrastructure sector," said Jagannarayan Padmanabhan, Director and Practice Leader, Transport & Logistics, Crisil Infrastructure Advisory. "Also many of the already identified sectors need a sustained policy push which will help them get visibility both in terms of quantum and the time period of applicability."

Till now, activities associated with laying of power and telecom transmission and distribution lines, roads, highways, railways and construction of facilities such as hospitals, affordable housing, power generation units, water treatment plants, SEZs and certain type of hotels amongst others were given such status.

Besides, these sectors are a part of harmonised master list for infrastructure sub-sectors. However, in April 2021, exhibition-cum-convention centre was included in the list. "Given the focus around electric vehicle, and need for significant investment in charging stations, if the government adds the sector in infrastructure list, the benefits arising out of it will be significant," said Vishal Kotecha, Director, India Ratings and Research. "Infra tag on sectors increases ability to raise funds, access to dedicated funds and lenders, foreign capital, lower interest rates among others."

Electric car Given the focus on electric vehicles, the advantages of including the industry in the infrastructure list will be enormous. Free SVG

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Wikipedia

A team is working to produce safest medicine for covid treatment.

A team led by chief scientist Ravi Shankar, is working on two combinations to provide the safest medication to coronavirus patients. "Experts say that a combination of antivirals with different mechanisms can be more effective to counter the viral pandemic. We are working on two combinations - Umifenovir with Molnupiravir (an antiviral) and Umifenovir with Niclosamide (anti-parasitic)," he said.

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Molnupiravur drug has received only Emergency Use Authorisation in India and abroad. Though its usage showed reduced hospitalisation during clinical trials, its biggest drawback are the side-effects, he added.

"Now, we are trying to keep a low dosage of Molnupiravir in its combination with Umifenovir which may weed out the side-effects such as the risk of cartilage and muscle damage. If successful, it will make Umifenovir more effective in Covid-19 treatment," said the chief scientist. The other combination is Umifenovir with Niclosamide.

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