Saturday March 24, 2018

‘It is Definitely a Woman’ ; DNA tests Reveal First Strong Evidence of a Female Viking Warrior

The researchers say it's the first confirmed remains of a high-ranking female Viking warrior

Programme cells
Scientists have found that cells can be programmed with pre-defined RNA commands, in the manner of a computer's microprocessor VOA

Berlin, September 12, 2017 : Scientists say DNA tests on a skeleton found in a lavish Viking warrior’s grave in Sweden show the remains are those of a woman in her 30s.

While bone experts had long suspected the remains belong to a woman, the idea had previously been dismissed despite other accounts supporting the existence of female Viking warriors.

Swedish researchers used new methods to analyze genetic material from the 1,000-year-old bones at a Viking-era site known as Birka, near Stockholm.

Charlotte Hedenstierna-Jonson of Uppsala University said Monday the tests show “it is definitely a woman.”

Hedenstierna-Jonson said the grave is particularly well-furnished, with a sword, shields, various other weapons and horses.

Writing in the American Journal of Physical Anthropology, the researchers say it’s the first confirmed remains of a high-ranking female Viking warrior.

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Nine new osteoarthritis genes discovered

The team looked for genes that were active in the progression of the disease by extracting the relevant cells from healthy and diseased tissue

Bone loss in adults. IANS
  • Researchers have discovered nine new genes responsible for osteoarthritis
  • These can help in developing new therapies
  • This research may also help in reducing the risk of the disease

Researchers have discovered nine novel genes for osteoarthritis that may open the door to new targeted therapies for this debilitating disease in the future.

Of the nine genes associated with osteoarthritis, researchers identified five genes in particular that differed significantly in their expression in healthy and diseased tissue.

These genes can help create new therapies.

The five genes present novel targets for future research into therapies, the researcher said. According to the researchers, there is no treatment for osteoarthritis. The disease is managed with pain relief and culminates in joint replacement surgery, which has variable outcomes.

“These results are an important step towards understanding the genetic causes of osteoarthritis and take us closer to uncovering the mechanism behind the disease,” said co-author of the study, Eleni Zengini from the University of Sheffield.

For the study, published in the journal Nature Genetics, researchers investigated the genetics behind osteoarthritis, as well as the diseases and traits that are linked to it.

The team studied 16.5 million DNA variations. Following combined analysis in up to 30,727 people with osteoarthritis and nearly 300,000 people without osteoarthritis in total — the controls –, scientists discovered nine new genes that were associated with osteoarthritis.

This may also help in finding ways to reduce the risk of the disease.

The researchers then investigated the role of the nine new genes in osteoarthritis, by studying both normal cartilage and diseased cartilage from individuals who had a joint replacement.

The team looked for genes that were active in the progression of the disease by extracting the relevant cells from healthy and diseased tissue, studying the levels of proteins in the tissue and sequencing the RNA — the messenger that carries instructions from DNA for controlling the production of proteins. IANS

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