Sunday November 17, 2019

Drinking Soft Drinks Linked to Obesity, Tooth Wear: Research

The study published in the journal Clinical Oral Investigations, found that being overweight or obese was undoubtedly associated with having tooth wear

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Soft Drinks
Increased consumption of sugary Soft Drinks may be a leading cause of the erosion of tooth enamel and dentine in obese patients. Pixabay

Researchers have found that sugar-sweetened acidic drinks, such as soft drinks, is the common factor between obesity and tooth wear among adults.

“It is the acidic nature of some drinks such as carbonated drinks and acidic fruit juices that leads to tooth wear,” said study lead author Saoirse O’Toole from King’s College London.

The study published in the journal Clinical Oral Investigations, found that being overweight or obese was undoubtedly associated with having tooth wear.

Significantly, they also found that the increased consumption of sugary soft drinks may be a leading cause of the erosion of tooth enamel and dentine in obese patients.

Previous research from King’s has found that tooth wear affects up to 30 per cent of European adults.

It is the premature wearing of teeth due to the softening of the dental enamel from dietary or gastric acids, combined with wear and tear.

Drawing on data from the National Health and Nutrition Examination Survey 2003-2004, the researchers analysed a representative sample of survey participants of 3,541 patients in the United States.

Patient BMI and the level of tooth wear were the exposure and outcome measurements in the analysis.

Soft Drinks
Researchers have found that sugar-sweetened acidic drinks, such as Soft Drinks, is the common factor between obesity and tooth wear among adults. Pixabay

The intake of sugar-sweetened acidic drinks was recorded through two non-consecutive 24-hour recall interviews where the patients were asked to provide details of diet intake across these two days.

According to the study, tooth wear is ranked as the third most important dental condition, after cavities and gum disease and the consumption of acidic food and drink is a leading cause of this.

Obese patients also have other risk factors such as increased likelihood of gastric reflux disease (heartburn) which was controlled for in this study.

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“This is an important message for obese patients who are consuming calories through acidic sugar sweetened drinks. These drinks may be doing damage to their body and their teeth,” O’Toole said. (IANS)

Next Story

Immune Cells Become Active and Repair Brain While Sleep: Study

For the findings, researchers conducted the study on mice

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Sleep
Study suggests that the enhanced remodeling of neural circuits and repair of lesions during Sleep may be mediated in part by the ability of microglia to dynamically interact with the Brain. Pixabay

Researchers have found that immune cells called microglia, which play an important role in reorganising the connections between nerve cells, fighting infections, and repairing damage, are also primarily active while we sleep.

Microglia serve as the brain’s first responders, patrolling the brain and spinal cord and springing into action to stamp out infections or gobble up debris from dead cell tissue.

“This research shows that the signals in our brain that modulate the sleep and awake state also act as a switch that turns the immune system off and on,” said study lead author Ania Majewska, Professor at University of Rochester in the US.

In previous studies, Majewska’s lab has shown how microglia interact with synapses, the juncture where the axons of one neuron connects and communicates with its neighbours.

The microglia help maintain the health and function of the synapses and prune connections between nerve cells when they are no longer necessary for brain function.

For the findings, researchers conducted the study on mice.

The current study points to the role of norepinephrine, a neurotransmitter that signals arousal and stress in the central nervous system.

This chemical is present in low levels in the brain while we sleep, but when production ramps up it arouses our nerve cells, causing us to wake up and become alert.

The study showed that norepinephrine also acts on a specific receptor, the beta2 adrenergic receptor, which is expressed at high levels in microglia.

When this chemical is present in the brain, the microglia slip into a sort of hibernation.

Sleep
Researchers have found that immune cells called microglia, which play an important role in reorganising the connections between nerve cells, fighting infections, and repairing damage, are also primarily active while we Sleep and affects Brain. Pixabay

The study, which employed an advanced imaging technology that allows researchers to observe activity in the living brain, showed that when mice were exposed to high levels of norepinephrine, the microglia became inactive and were unable to respond to local injuries and pulled back from their role in rewiring brain networks.

“This work suggests that the enhanced remodeling of neural circuits and repair of lesions during sleep may be mediated in part by the ability of microglia to dynamically interact with the brain,” said study first author Rianne Stowell.

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“Altogether, this research also shows that microglia are exquisitely sensitive to signals that modulate brain function and that microglial dynamics and functions are modulated by the behavioural state of the animal,” Stowell said.

The study was published in the journal Nature Neuroscience. (IANS)