Thursday November 21, 2019

Drug Used For Osteoporosis May Help in Reducing Heart Attack Risk

Intake of the drug also reduced the risk of stroke by 18 per cent within five years and 17 per cent within 10 years.

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A commonly used drug for treating osteoporosis or bone pain may also help reduce the risk of death by cardiovascular, heart attack and stroke, according to a study.
Heart Attack risk can be decreased by drug of osteoporosis. Pixabay

A commonly used drug for treating osteoporosis or bone pain may also help reduce the risk of death by cardiovascular, heart attack and stroke, according to a study.

The report, published in Journal of Bone and Mineral Research, showed that the drug Alendronate could lower the risk of cardiovascular diseases by 67 per cent and heart attacks by 45 per cent within a year.

Intake of the drug also reduced the risk of stroke by 18 per cent within five years and 17 per cent within 10 years.

“Our findings show that Alendronate is potentially cardioprotective in hip fracture patients,” said Ching-Lung Cheung, from the University of Hong Kong.

“Physicians should consider prescribing Alendronate or other similar drugs to patients with hip fracture and patients should also have good compliance with Alendronate treatment, as this is not only good for your bones but also your heart,” Cheung added.

It is used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
Spine Bones, Pixabay

Alendronate belongs to a class of drugs called bisphosphonates and works by preventing bone breakdown and increasing bone density.

It is used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.

The researchers collected data from 34,991 patients, diagnosed with hip fracture in 2005. Out of these 4,602 patients received osteoporosis treatment during follow up.

Also Read: Healthy Diet May Decrease the Risk of Hearing Loss in Women 

Due to excess cardiovascular adverse events, there is a worldwide crisis in the current treatment of osteoporosis with drug romosozumab.

In 2017, the US Food and Drug Administration (FDA) had rejected romosozumab and requested more data before reaching a decision.

The study, thus, has significant implications in clinical trial design of anti-osteoporosis medications, the researchers said. (IANS)

Next Story

Listen To Music To Reduce Cardiac Stress While Driving

Listening to music while driving can reduce cardiac stress

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Reducing stress
Researchers found that listening to music while driving reduces cardiac stress. Pixabay

Stress while driving is a risk factor for the development of cardiovascular disease and sudden cardiac complications such as heart attack, but now researchers have found that listening to music while driving can reduce cardiac stress.

“We found that cardiac stress in the participants in our experiment was reduced by listening to music while they were driving,” said study lead author Vitor Engracia Valenti, Professor at Sao Paulo State University in Brazil.

For the study, published in the journal Complementary Therapies in Medicine, researchers analysed the effects of music on cardiac stress in five women between the ages of 18 and 23.

“We opted to assess women who were not habitual drivers because people who drive frequently and have had a license for a long time are better adapted to stressful situations in traffic,” Valenti explained.

The volunteers were assessed on two days, in different situations and in a random order.

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Researchers analysed the effects of music on cardiac stress in five women between the ages of 18 and 23. Pixabay

On one day, they drove for 20 minutes at rush hour (5:30-6:30 pm) along a three km route in a busy district of Marilia, a medium-sized city in the northwest of Sao Paulo, without listening to music.

On the other day, the volunteers drove the same route at the same time of day but listened to instrumental music on a CD player coupled to the car radio.

The use of earbuds or headphones while driving is a traffic offense.

“To increase the degree of traffic stress, we asked them to drive a car they did not own. Driving their own car might help,” Valenti said.

The level of cardiac stress was estimated by measuring heart rate variability using a heart rate monitor attached to the participant’s chest.

Defined as fluctuations in the intervals between consecutive heart beats, heart rate variability is influenced by the autonomic nervous system.

The more active the sympathetic nervous system, the faster the heart beats, while the parasympathetic nervous system tends to slow it down.

“Elevated sympathetic nervous system activity reduces heart rate variability, whereas more intense parasympathetic nervous system activity increases it,” Valenti said.

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The level of cardiac stress was estimated by measuring heart rate variability using a heart rate monitor attached to the participant’s chest. Pixabay

Analysis showed a reduction in heart rate variability in the volunteers who drove without music, indicating a lower level of parasympathetic nervous system activity but sympathetic nervous system activation.

Conversely, heart rate variability increased in the drivers who listened to music, indicating a higher level of parasympathetic nervous system activity and a reduction in sympathetic nervous system activity.

However, the sample size used in the study was too small but significant.

“Listening to music attenuated the moderate stress overload the volunteers experienced as they drove,” Valenti said.

Also Read- Here’s Why Women Should Not Dine After 6 PM

“Listening to music could be such a preventive measure in favour of cardiovascular health in situations of intense stress such as driving during rush hour,” he said. (IANS)