Sunday March 24, 2019

Drug Used For Osteoporosis May Help in Reducing Heart Attack Risk

Intake of the drug also reduced the risk of stroke by 18 per cent within five years and 17 per cent within 10 years.

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A commonly used drug for treating osteoporosis or bone pain may also help reduce the risk of death by cardiovascular, heart attack and stroke, according to a study.
Heart Attack risk can be decreased by drug of osteoporosis, Pixabay

A commonly used drug for treating osteoporosis or bone pain may also help reduce the risk of death by cardiovascular, heart attack and stroke, according to a study.

The report, published in Journal of Bone and Mineral Research, showed that the drug Alendronate could lower the risk of cardiovascular diseases by 67 per cent and heart attacks by 45 per cent within a year.

Intake of the drug also reduced the risk of stroke by 18 per cent within five years and 17 per cent within 10 years.

“Our findings show that Alendronate is potentially cardioprotective in hip fracture patients,” said Ching-Lung Cheung, from the University of Hong Kong.

“Physicians should consider prescribing Alendronate or other similar drugs to patients with hip fracture and patients should also have good compliance with Alendronate treatment, as this is not only good for your bones but also your heart,” Cheung added.

It is used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
Spine Bones, Pixabay

Alendronate belongs to a class of drugs called bisphosphonates and works by preventing bone breakdown and increasing bone density.

It is used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.

The researchers collected data from 34,991 patients, diagnosed with hip fracture in 2005. Out of these 4,602 patients received osteoporosis treatment during follow up.

Also Read: Healthy Diet May Decrease the Risk of Hearing Loss in Women 

Due to excess cardiovascular adverse events, there is a worldwide crisis in the current treatment of osteoporosis with drug romosozumab.

In 2017, the US Food and Drug Administration (FDA) had rejected romosozumab and requested more data before reaching a decision.

The study, thus, has significant implications in clinical trial design of anti-osteoporosis medications, the researchers said. (IANS)

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Cardiovascular Events Cause 58% Deaths Among Diabetics

The medicine likewise helps lower the amount of sodium in the body and reduce triglyceride levels and blood pressure

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Diabetes
Representational image. Pixabay

Fifty-eight percent of deaths among people with type 2 diabetes are due to cardiovascular events, a leading Mexican expert has said.

“Patients who live with this disease have a greater risk of premature death or disability derived from cardiovascular events,” Hector Sanchez Mijangos, President of the Mexican Diabetes Federation, told Efe news.

The specialist said that the high glucose levels associated with diabetes damage blood vessels, resulting in problems with blood pressure and vision, joint pain and other maladies.

Data from the World Health Organization indicate that more 442 million people suffer from type 2 diabetes.

Mexico’s Health Secretariat has found that while roughly 13 million inhabitants of the Aztec nation are living with diabetes, only half of those afflicted know they have the disease.

In 2015 alone, according to Mijangos, there were more than 98,000 premature deaths in Mexico related to diabetes and the average age of those who died was 66.7 years old.

Diabetes
Representational image. Pixabay

“This is regrettable, because these people could have lived roughly another 15 years,” he said.

According to the 2012 National Health and Nutrition Survey, only 25 percent of Mexicans suffering with diabetes are managing their condition adequately.

That figure illustrates “why our greatest challenge continues to be access and adherence to treatment”, Mijangos said.

Also Read- Researchers Discover Balance of Two Enzymes That May Help Treat Pancreatic Cancer

To improve treatment options, Mexican health authorities in January issued an approval for the use of canagliflozin, a drug that helps reduce the amount of blood glucose reabsorbed by the kidneys, which in turns causes more glucose to be eliminated through urination.

“With this medicine, a person can lose 100 milligrams of glucose per day as well as about 400 kilocalories (4,000 calories) a day, which also helps with weight loss,” Mijangos said.

The medicine likewise helps lower the amount of sodium in the body and reduce triglyceride levels and blood pressure.

A scientific trial involving more than 10,000 patients worldwide showed that when combined with conventional treatment, canagliflozin can reduce the incidence of cardiovascular events by up to 18 percent. (IANS)