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What is anxiety?
Anxiety Disorder is a completely normal response to perceived threats to your wellbeing. Whether it be a driving test, difficult exam or job interview, these are all situations which can commonly be labelled as ‘stressful’.
Any stressor can lead to anxiety, which is best described as an unpleasant feeling of intense fear. Regular levels of anxiety accompanying a stressful situation is a completely normal bodily reaction, but anxiety often morphs into disorders which can be hard to overcome.
Anxiety disorders are a fact of life for many. These occur when the body’s normal response to stress becomes out of hand, and it begins to produce an anxiety response to harmless situations.
A couple of examples of anxiety disorders include:
- Social anxiety disorder. This is defined by a strong anxiety triggered by social situations, particularly ones such as talking in groups, talking to unfamiliar people or giving a speech. The root fear is being judged negatively by others in social situations.
- Phobias. Phobias are classified as anxiety disorders, as they consist of an extreme fear response to a particular stimuli. A common phobia is arachnophobia, extreme anxiety and fear caused by spiders.
As seen from the examples, anxiety disorders are often centred around stimuli which are not anxiety-provoking for the whole population. That is the key when it comes to disorders.
What can we do to reduce anxiety?
There are multiple common remedies for anxiety, including the following:
- Therapy, such as cognitive behavioural therapy (CBT).
- Mindfulness and meditation.
- low carb diets can be anti-inflammatory and in some cases decreases neuro-psychiatric symptoms.
- Drug-related intervention, from herbal teas and cannabidiol oil to prescription medication like Prozac..
The final bullet is the one that we will focus on in this article, as want to gauge how drugs impact anxiety levels, and the testing which has gone into this.
Natural remedies including lifestyle changes such as exercise are often suggested as remedies for mild anxiety. Therapy is often suggested if anxiety becomes a real problem in someone’s life.
There is also a sliding scale of drug-related solutions. Herbal tea could be used to cure mild anxiety, whereas somebody would be prescribed medication like Prozac if their anxiety is severe.
How are drugs used to treat anxiety?
Different medication is prescribed depending on the severity of anxiety. For example, antidepressants and SSRIs such as Prozac, Zoloft and Paxil would only be administered if a patient was suffering from chronic anxiety. In this case, the drugs act on the brain’s neural pathways to alter the way in which the neurotransmitter serotonin is used.
Alternatively, antihistamines and beta-blockers are often recommended for more mild cases of anxiety. Rather than being taken daily in order to restructure the brain’s behavior, these are usually taken when anxiety occurs or before an anxiety-producing event.
For immediate relief of more acute anxiety, benzodiazepines such as diazepam and clonazepam are usually taken. However, these often receive bad press for their side effects which can include drowsiness, irritability and a physical dependence on the drug.
How do we find out which anti-anxiety drugs are safe for human use? Ethical animal testing is often the answer.
Testing for anti-anxiety solutions, particularly in rodents
Rodents are often used in scientific experiments which aim to identify new treatments for anxiety in humans. Considering the relative similarities of key brain structures, we can observe the effects of anxiety-provoking situations on rodents to know which parts of the brain could be involved in anxiety responses.
Lezak, 2017, provides excellent discussion on the testing of rodents for anxiety-like symptoms. He describes the stimuli we provide as ‘assays’, rather than ‘models’. By definition, a model is required to have extreme detail and be thoroughly tested.
One assay commonly used for anxiety measurement in rodents is the Open Field Test. This really is a basic test, involving a box in which a rodent is placed. The box is lined with tall walls which can be set to either clear or opaque.
Typically, a rodent feeling more anxiety-like would tend to stick close to the walls of the box, and venture out into the middle very little. Conversely, a ‘happy’ rodent would be explorative, and spend time in the open space in the middle of the box. It is also possible to analyze other behaviors of the rodent such as rearing, grooming and freezing, to judge its levels of confidence in its surroundings.
A simple study into measuring the effects of drugs on rodents in an Open Field Test would be to administer a benzodiazepine and record the difference in anxiety-like behaviors. There have been studies which confirm the reduction in rodent anxiety-like behaviors after administering a benzodiazepine, but which also report other changes in behavior such as shifts in locomotor pattern.
Any unexpected or additional effects which drugs have on rodents must be seriously considered before a drug is approved for human usage.
Can drugs also contribute to anxiety negatively?
So far, we have covered the ways in which drugs can be used to treat anxiety. However, it is also true that certain drugs can worsen the symptoms of anxiety.
Substance-induced anxiety disorders are the name given to anxiety, panic and fear caused by the taking of a drug, or stopping taking a drug.
Alcohol, as well as illegal drugs such as cocaine and LSD can be responsible for substance-induced anxiety disorders. This may be because of thoughts associated with the use of the drugs: “I’m worried that I’m too dependent on this drug”, “I know that if I stop taking this drug, my anxiety levels will go through the roof”.
As well as fear caused by the drug, there are other symptoms like insomnia, memory loss and difficulty breathing which can all contribute to increased anxiety levels after taking these drugs.
Abuse of stimulants and steroids in particular will cause a pounding, irregular heartbeat and racing thoughts.
In short, misusing any type of drug can lead to substance-induced anxiety disorders. If you already suffer from anxiety, the best course of action is to consult a doctor and take the drugs recommended to you, in their recommended doses.
The power of drugs on our mental wellbeing
It is clear that drugs have the capacity to affect our mental state in both positive and negative ways. In particular, anxiety is a symptom easily influenced by psychoactive drugs.
Understanding exactly what anxiety is, as well as knowing which types of drugs fit each severity level, will go a long way to fighting this disruptive mental disorder off.
Shuhan He is a physician and scientist, founder of ConductScience.com – a company that creates translational science tools for outcomes in science. The aim of the company is to improve the scientific community by making it easier to access top-quality scientific equipment.
He also works as an emergency medicine physician at the Massachusetts General Hospital.
What Is Bullying?
Bullying is a pattern of recurrent aggressive behavior in which one person (or a group of individuals) in a position of authority intentionally intimidate or abuse another individual to cause bodily or emotional harm to that other. Bullying may take place in either a physical or verbal manner. Bullied individuals, as well as those who bully others, may have long-term repercussions.
Bullying may occur anywhere, at any time, in person or online (cyberbullying), and can take many forms, including verbal, physical, and social. Bullies utilize their position of power — such as physical strength, knowledge of something embarrassing, or popularity — to exert control over or damage other people. Many people assume that bullying occurs solely during childhood; nevertheless, bullying does not necessarily stop after a person reaches the age of adulthood.
Bullies in adulthood can take the form of a threatening boss or colleague, a controlling partner, a relative, or any other type of person. Even in our personal and professional lives, we sometimes encounter adult bullies who can be harmful to our mental well-being.
Bullied individuals, as well as those who bully others, may have long-term repercussions. | Photo by Unsplash
How To Deal With An Adult Bully?
For obvious reasons, adult bullying can be a painful and challenging experience for anybody who finds themselves on the receiving end of such behavior. Knowing how to deal with the antics of a bully properly, on the other hand, may help you learn, develop, and feel better levels of confidence. When you find yourself in this scenario, one of the most crucial things to remember is that you must not exhibit the bully any signs of fear. This might be difficult, depending on the sort of bully you are dealing with, but bullies enjoy fear, encouraging them to continue with their terrible conduct.
Maintaining a sense of connection with other people while dealing with bullying is quite essential. Bullies usually see alone persons as easier targets since they have a smaller support network to challenge them.
Courage and a support network are significant advantages; but, reporting the bully is also an excellent line of action. Contrary to common opinion, just ignoring a bully does not always prompt them to cease their behavior. Adult bullies of all kinds often interpret being ignored as a sign of weakness, encouraging them to continue bullying. If someone is bullying you, don't be scared to speak out and report the individual.
No one can make you feel inferior without your consent ~Eleanor Roosevelt
Keywords: mental health, bullying, bully, bullied, courage, abuse, harass, support, cyberbully
Silver and gold have always been preferred when it comes to wearing jewellery. Right from the times of monarchy in India, wealth and riches have been associated with wearing gold and silver for the various properties they have. Copper is a metal that has always been worn by the poor. It is not a metal that carries a significant association with health or wealth, but wearing at least one article of copper is extremely beneficial for health.
Copper is a reddish-brown metal that cannot be worn on its own. It has to be worn in the form of an alloy to prevent a reaction. Copper oxidizes in air and forms a green layer on it when exposed, much like the Statue of Liberty. Usually, bangles, chains, or rings of copper always have brass and traces of silver in them which helps with stabilizing its reactivity.
Wearing copper with stones in it looks very aesthetic, but copper is not durable enough to hold the stones, which is why it is fashioned into elaborate designs and sold. Copper is very malleable, and over time, the bangle or ring will take the shape of the wearer's hand or finger.
A copper ring Image source: Wikimedia commons
Jewellery made out of copper can be an excellent health indicator. Copper helps metabolize bodily functions faster, and the wearer experiences relief from indigestion. It also soothes joint pain, headaches, and arthritis. Using copper utensils also aids those with deficiencies. Since copper is absorbed slowly into the body, there is no fear of causing any kind of imbalance.
Sometimes copper leaves a greenish tinge on the skin. This happens when it oxidizes with sweat. This stain can be washed away with soap and water, but the fact that it appears is noteworthy. It is an indicator of too much acidity in the body. Greenish skin appears when the wearer's diet includes too much meat or acidic foods.
Copper might not be a very attractive metal, but wearing it has a lot of benefits for the health. It regulates metabolism, assimilation, and indicates health. It is definitely a good idea to wear copper jewellery at least once in a while.
Keywords: Copper jewellery, Copper is a health indicator, Metabolism, Oxidation, Benefits of copper
By Md Waquar Haider
When popular smartphone brands like Xiaomi and realme entered the laptop market in India last year, they were expected to shake the existing giants, specifically under the Rs 50,000 category. However, chip shortage and supply crunch have somewhat dented their plans to make a significant mark to date. According to industry experts, the issue with smartphone makers entering the laptop category is two-fold. The first one is a massive supply crunch in the laptop component market and only big brands are able to get volume and supplies.
The other factor is that the traditional players are very strong in the consumer laptop market. Top 3 players control more than 70 per cent of the market and strong portfolio, distribution, and channel reach as well as brand marketing has helped them massively. "New brands can surely make a dent in the consumer laptop market but are challenged by supply issues right now. Watch out for them in 2022 as and when supply situation eases up," Navkendar Singh, Research Director, Client Devices & IPDS, IDC India told IANS.
Dominated by HP Inc, Lenovo and Dell, the traditional PC market (inclusive of desktops, notebooks, and workstations) in India continued to be robust as the shipments grew by 50.5 per cent year-over-year (YoY) in the second quarter (Q2), according to IDC. Notebook PCs continue to hold more than three-fourth share in the overall category and grew 49.9 per cent YoY in 2Q21, reporting a fourth consecutive quarter with over 2 million units. Desktops also indicated a recovery as shipments grew 52.3 per cent YoY after recording the lowest shipments of the decade in 2Q20.
According to Prabhu Ram, Head, Industry Intelligence Group, CMR, driven by the pandemic and the associated accelerated pivot to remote work, learn and unwind culture, PCs have been witnessing heightened demand. "Despite the current supply chain constraints, PCs are here to stay in the new never normal. In the run-up to the festive season, established PC market leaders will continue to leverage their brand salience and gain market share," Ram told IANS.
According to industry experts, the issue with smartphone makers entering the laptop category is two-fold. | Photo by Manuel on Unsplash
"On the other hand, there is a niche market for those new market entrants that are able to differentiate themselves from the competition in terms of features and value. "Alongside, they would need to back it with strong brand messaging to create awareness and recall amongst the target consumers," Ram added.
HP maintained its lead in the India PC market with a 33.6 per cent share as its shipments grew 54.2 per cent annually. Dell Technologies continued to hold the second position with a 22.1 per cent share and an impressive 86.1 per cent YoY growth in 2Q21. Lenovo maintained the third position with a share of 17.8 per cent in 2Q21.
Arvind Suraj, Research Fellow, Jawaharlal Nehru University (JNU), said that there is always a trust issue with new brands. "You won't buy a laptop in 6 or 7 months just like smartphones. In this case, we often go for existing players. Brands like Lenovo, HP, ASUS and Acer have already gained our trust," he said. (IANS/ MBI)
Keywords: Chip, shortage, laptop, market, India, Xiaomi, hp, dell, brands