Friday November 15, 2019

Drugs That Suppress Immune System May Protect Against Parkinson’s

Immunosuppresive drugs likely to keep Parkinson's at bay

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Your work emails can affect your health, relationships
Your work emails can affect your health, relationships Pixabay

People who are on drugs to suppress their immune system are less likely to develop Parkinson’s disease — a neurological disorder characterised by tremors, slow movements, stiffness and difficulty walking, a new study claimed.

The results, published in the journal Annals of Clinical and Translational Neurology, showed that people with several types of autoimmune diseases, including ulcerative colitis were less likely to be diagnosed with Parkinson’s than the general population.

The investigators noted that many autoimmune diseases have one common thing, that is, they are treated with drugs that dampen immune activity.

“We’ve found that taking certain classes of immunosuppressant drugs reduces the risk of developing Parkinson’s. One group of drugs in particular looks really promising and warrants further investigation to determine whether it can slow disease progression,” said Brad Racette from Washington University-St. Louis in the US.

Representational image.
Representational image. Pixabay

The study showed that people taking corticosteroids — used for treating inflammatory diseases — such as prednisone were 20 per cent less likely to be diagnosed with Parkinson’s, while those on inosine monophosphate dehydrogenase (IMDH)– an enzyme — inhibitors were about one-third less likely.

While, immunosuppresive drugs may keep Parkinson’s at bay, it may ,however, increase the chances of developing infectious diseases and cancer.

The benefits of these drugs outweigh the costs for people with serious autoimmune diseases like rheumatoid arthritis but doctors would probably hesitate to prescribe risky drugs to healthy people to stave off Parkinson’s, especially since there is no reliable way to predict who is on track to develop the disease, the team explained.

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“What we really need is a drug for people who are newly diagnosed, to prevent the disease from worsening. It’s a reasonable assumption that if a drug reduces the risk of getting Parkinson’s, it also will slow disease progression, and we’re exploring that now,” Racette said.

For the study, the team analysed prescription drug data on 48,295 people diagnosed with Parkinson’s and 52,324 people never diagnosed with Parkinson’s and developed an algorithm to predict which people would be diagnosed with the disease. (IANS)

Next Story

Researchers Find That Discount on Medical Drugs Can Make you Purchase Them More

The study used Canadian national pharmacy data from 2.82 million prescriptions for 89 different medications where brand-name drug discount cards were used and compared

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Discount
While Discount cards decreased some patients' out-of-pocket costs by 7 per cent on an average, the study surprisingly found that many patients who filled prescriptions using a card were worse-off financially as a result. Pixabay

Researchers have found that brand-name Drug Discount cards are leading to higher healthcare spending in Canada.

Brand-name drug discount cards — also known as co-pay cards — are coupons offered by drug manufacturers to encourage patients to use brand-name drugs even after much cheaper generics became available.

Despite often boosting savings for customers, the study’s findings published in the Canadian Medical Association Journal show that drug discount cards actually increased private insurer costs by 46 per cent and public insurer costs by 1.3 per cent, compared to patients purchasing generics instead.

“We know that generic drugs are equally effective for the vast majority of patients. Given that, I believe these cards are leading to unjustifiable increases in health care costs,” said the study’s lead author Michael Law from the University of British Columbia in Canada.

While discount cards decreased some patients’ out-of-pocket costs by 7 per cent on an average, the study surprisingly found that many patients who filled prescriptions using a card were worse-off financially as a result.

This wasn’t the case for all drugs, but in some cases patients could pay up to $10 more out-of-pocket when using a discount card.

The study used Canadian national pharmacy data from 2.82 million prescriptions for 89 different medications where brand-name drug discount cards were used and compared the costs of these prescriptions to matched generic equivalents.

Discount
Researchers have found that brand-name Drug Discount cards are leading to higher healthcare spending in Canada. Pixabay

The researchers said that patients, their clinicians and employers should be aware of the impact that brand-name discount cards have on the healthcare system.

For example, the increased costs to private insurers will likely be passed on to the patients and their employers in the form of increased insurance premiums.

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“Regardless of whether they hold insurance, patients should check the relative price between brand-name drugs with a discount card and the equivalent generics at their pharmacy,” said Law. (IANS)