Wednesday June 26, 2019

Flavoured E-Cigarettes Increase the Risk of Cardiovascular Diseases

"This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes," said Joseph Wu, Professor at Stanford University

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E-cigarette additives impair lung function: Study.

The flavours used in electronic cigarettes (e-cigarette), especially cinnamon and menthol, can increase the risk of cardiovascular diseases (CVD) when inhaled, says a study. The research team investigated the effect of the e-liquids on endothelial cells that line the interior of blood vessels.

The study, published in the Journal of the American College of Cardiology, found that endothelial cells exposed to the e-liquids or to blood collected from e-cigarette users shortly after vaping, exhibit significantly increased levels of molecules implicated in DNA damage and cell death.

The severity of the damage, aspects of which occur even in the absence of nicotine, varies among popular flavours, said the researchers, adding that cinnamon and menthol were found to be particularly harmful. “This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes,” said Joseph Wu, Professor at Stanford University.

E-cigarettes, Smokers
A woman smokes an electronic cigarette in London, Aug. 19, 2015. VOA

For the study, the researchers investigated the effect of six different popular e-liquid flavours — fruit, tobacco, sweet tobacco with caramel and vanilla, sweet butterscotch, cinnamon and menthol — with varied nicotine levels on endothelial cells derived from human induced pluripotent stem cells or iPS cells.

ALSO READ: UK Study: E-Cigarettes help Smokers Quit as Much as Stop-Smoking Aids

“When we exposed the cells to six different flavours of e-liquid with varying levels of nicotine, we saw significant damage. The cells were less viable in culture, and they began to exhibit multiple symptoms of dysfunction,” Wu said.

The researchers found that while several of the liquids were moderately toxic to the endothelial cells, the cinnamon- and menthol-flavoured e-liquids significantly decreased the viability of the cells in culture even in the absence of nicotine. “It’s important for e-cigarette users to realise that these chemicals are circulating within their bodies and affecting their vascular health,” Wu said. (IANS)

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Why Do Women Face Higher Heart Disease Risk after Breast Cancer? Find Out Here!

The cardiovascular effects may occur more than five years after radiation exposure

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Women, Heart Disease, Breast Cancer
Heart disease appears more commonly in women treated for breast cancer because of the toxicities of chemotherapy. Pixabay

Researchers have found that postmenopausal women with breast cancer are at greater risk of developing cardiovascular disease.

“Heart disease appears more commonly in women treated for breast cancer because of the toxicities of chemotherapy, radiation therapy and use of aromatase inhibitors, which lower estrogen,” said JoAnn Pinkerton, Professor at the University of Virginia.

The cardiovascular effects may occur more than five years after radiation exposure, with the risk persisting for up to 30 years.

“Heart-healthy lifestyle modifications will decrease both the risk of recurrent breast cancer and the risk of developing heart disease,” Pinkerton said.

Women, Heart Disease, Breast Cancer
Researchers have found that postmenopausal women with breast cancer are at greater risk of developing cardiovascular disease. Pixabay

The goal of the study was to compare and evaluate risk factors for cardiovascular disease in postmenopausal women who are survivors of breast cancer and women without breast cancer.

For the findings, more than 90 postmenopausal breast cancer survivors were compared with 192 postmenopausal women.

The researchers found that postmenopausal women who are survivors of breast cancer showed a markedly stronger association with metabolic syndrome, diabetes, atherosclerosis, hypertriglyceridemia and abdominal obesity, which are major risk factors for cardiovascular disease.

The risk of cardiovascular mortality similarly increased to match death rates from cancer itself.

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“Women should schedule a cardiology consultation when breast cancer is diagnosed and continue with ongoing follow-up after cancer treatments are completed,” she added.

The study was published in the Menopause: The Journal of the North American Menopause Society. (IANS)