Friday October 18, 2019

Flavoured E-Cigarettes Increase the Risk of Cardiovascular Diseases

"This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes," said Joseph Wu, Professor at Stanford University

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E-cigarette additives impair lung function: Study.

The flavours used in electronic cigarettes (e-cigarette), especially cinnamon and menthol, can increase the risk of cardiovascular diseases (CVD) when inhaled, says a study. The research team investigated the effect of the e-liquids on endothelial cells that line the interior of blood vessels.

The study, published in the Journal of the American College of Cardiology, found that endothelial cells exposed to the e-liquids or to blood collected from e-cigarette users shortly after vaping, exhibit significantly increased levels of molecules implicated in DNA damage and cell death.

The severity of the damage, aspects of which occur even in the absence of nicotine, varies among popular flavours, said the researchers, adding that cinnamon and menthol were found to be particularly harmful. “This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes,” said Joseph Wu, Professor at Stanford University.

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A woman smokes an electronic cigarette in London, Aug. 19, 2015. VOA

For the study, the researchers investigated the effect of six different popular e-liquid flavours — fruit, tobacco, sweet tobacco with caramel and vanilla, sweet butterscotch, cinnamon and menthol — with varied nicotine levels on endothelial cells derived from human induced pluripotent stem cells or iPS cells.

ALSO READ: UK Study: E-Cigarettes help Smokers Quit as Much as Stop-Smoking Aids

“When we exposed the cells to six different flavours of e-liquid with varying levels of nicotine, we saw significant damage. The cells were less viable in culture, and they began to exhibit multiple symptoms of dysfunction,” Wu said.

The researchers found that while several of the liquids were moderately toxic to the endothelial cells, the cinnamon- and menthol-flavoured e-liquids significantly decreased the viability of the cells in culture even in the absence of nicotine. “It’s important for e-cigarette users to realise that these chemicals are circulating within their bodies and affecting their vascular health,” Wu said. (IANS)

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Regular Exercise Highly Beneficial for All Patients with Cardiovascular Disease Regardless of Age

However, there is few data available about the impact of patient age on the physical and psychological effectiveness of cardiac rehabilitation

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Exercise, Patients, Cardiovascular Disease
As a result, elderly patients are usually less fit than their younger counterparts, and deconditioning is accelerated once cardiovascular disease is established. Pixabay

Regular exercise is highly beneficial for all patients with cardiovascular disease regardless of age, a new study has said, adding that patients who benefited most from cardiac rehabilitation were those who started out with the greatest physical impairment.

Ageing is associated with several factors such as increased inflammation or oxidative stress that predispose people to cardiovascular diseases.

“As a result, elderly patients are usually less fit than their younger counterparts, and deconditioning is accelerated once cardiovascular disease is established,” explained lead investigator Gaelle Deley from University of Burgundy Franche-Comt in France.

However, there is few data available about the impact of patient age on the physical and psychological effectiveness of cardiac rehabilitation, said the study published in the Canadian Journal of Cardiology.

Exercise, Patients, Cardiovascular Disease
Ageing is associated with several factors such as increased inflammation or oxidative stress that predispose people to cardiovascular diseases. Pixabay

In the new study, investigators examined 733 patients who completed a 25-session cardiac rehabilitation programme.

Following the intervention, all patients experienced improvements.

“We found a few weeks of exercise training not only significantly improved exercise capacity, but also decreased anxiety and depression. Patients with the greatest physical impairments at baseline benefited the most from exercise,” said Dr Deley.

Another interesting result was that patients younger than 65 who were very anxious before rehabilitation benefited the most from exercise training.

Also Read- WHO Calls for Developing and Implementing Strategies to Prevent Suicide and Promote Mental Health

A similar result was found for depressed patients older than 65.

Cardiovascular diseases are the main cause of death globally. While cardiovascular diseases increasingly affect young people, the number of people above the age of 65 years, and even more above the age of 80 years, dying from cardiovascular diseases is also increasing. (IANS)