Friday May 25, 2018

Early Puberty in Girls May be a Result of Obesity in Mothers’

Maternal overweight and hyperglycemia or high blood sugar are linked to the earlier onset of puberty in girls, which can lead to multiple adverse health developments in adulthood, finds a study. The results showed that maternal obesity (body mass index of 30 or more) and overweight (body mass index between 25 and 30) in mothers was associated with 40 per cent and 20 per cent greater chance of earlier breast development in girls aged 6 to 11, respectively.

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Foetal immune rejection may be one of the causes for preterm labour -- a common pregnancy complication leading to birth occurring before the 37th week of pregnancy, researchers say.
Pregnant Woman, Pixabay
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Maternal overweight and hyperglycemia or high blood sugar are linked to the earlier onset of puberty in girls, which can lead to multiple adverse health developments in adulthood, finds a study.

The results showed that maternal obesity (body mass index of 30 or more) and overweight (body mass index between 25 and 30) in mothers was associated with 40 per cent and 20 per cent greater chance of earlier breast development in girls aged 6 to 11, respectively.

“We know that maternal weight can influence childhood weight. What we are learning is that the utero environment may also affect the timing of future pubertal development in offspring, which makes sense since human brains are developed in utero and the brain releases hormones affecting puberty,” said lead author Ai Kubo, research scientist with the Kaiser Permanente Northern California Division of Research.

The study also found a significant relationship between hyperglycemia (elevated blood sugar during pregnancy) in mothers and the earlier onset of breast development, but not in mothers with gestational diabetes.
Representational image. Pixabay

Similar associations between maternal obesity and earlier onset were also linked with the development of pubic hair.

The study also found a significant relationship between hyperglycemia (elevated blood sugar during pregnancy) in mothers and the earlier onset of breast development, but not in mothers with gestational diabetes.

“It’s possible that women with the diagnosis of gestational diabetes were more careful about weight and diet, which might have changed the amount of weight gain and offspring development patterns, but other studies need to replicate the finding to be able to conclude that there is an association,” Kubo noted.

Evidence from epidemiologic data has also shown the beneficial effects of breastfeeding on the health of infants and their mothers. Pixabay
Baby Girl. pixabay

For the study, published in the American Journal of Epidemiology, the team included more than 15,000 girls and their mothers.

Also Read: Teenaged mothers at high risk for heart diseases later

Previous researches have demonstrated that early puberty, including the early onset of breast development or menarche (initiation of menstruation), increases the risk of adverse health outcomes including obesity, Type 2 diabetes, polycystic ovarian syndrome, and cancer in adolescence and adulthood.

For girls, it has been linked to a higher risk of adverse emotional and behavioural outcomes including depression, anxiety, earlier sexual initiation and pregnancy. (IANS)

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Study Shows Weight Loss Surgery Can Reduce Risk of Skin Cancer

Bariatric surgery, a weight loss operation, is associated with a 61 per cent decrease in the risk of developing malignant skin cancer, according to a study.

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Bariatric Surgery
representational image. Pixabay

Bariatric surgery, a weight loss operation, is associated with a 61 per cent decrease in the risk of developing malignant skin cancer, according to a study.

Melanoma is a deadly form of skin cancer, most closely associated with excessive sun exposure. Obesity is an established risk factor for cancer and some studies indicate that intentional weight loss sometimes reduces the risk.

However, evidence for a link between obesity, weight loss and malignant melanoma is limited.

The new findings showed that bariatric surgery led to a 42 per cent reduced risk of skin cancer in general compared to controls given usual obesity care.

The study “supports the idea that obesity is a melanoma risk factor and indicates that weight loss in individuals with obesity can reduce the risk of bariatric surgery that has increased steadily in many countries over several decades”, said lead author Magdalena Taube from the University of Gothenburg in Sweden.

Cancer word on newspaper
Cancer. Pixabay

The results were presented at the 2018 European Congress on Obesity in Vienna, Austria.

The protective effect of bariatric surgery on skin cancer was observed in a group of 2,007 obese participants who were then followed for a median of 18 years.

These were compared with a control group consisting of 2,040 individuals who matched with the participants who underwent surgery on sex, age, anthropometric measurements, cardiovascular risk factors, psychosocial variables and personality traits.

Also Read: Study Shows that Humans Are Influencing Cancer in Wild Animals

To analyse malignant melanoma incidence, statistical tests were used to compare time to first melanoma cancer diagnosis between the surgery and control groups.

In additional analyses, risk ratios between the surgery and control groups were compared. (IANS)