Saturday April 4, 2020

Eating in 10-hours Window May Boost Health

Many of us may have one or more disease-causing defective genes that make us feel helpless and destined to be sick. The finding that a good lifestyle can beat the bad effects of defective genes opens new hope to stay healthy

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Health
Anorexia nervosa is an eating disorder that makes people obsessive about their weight. Pixabay

Following a simple lifestyle such as eating all food within 10 hours can restore balance, stave off metabolic diseases and maintain health, suggests a study led by one of an Indian-origin.

The study, conducted over mice, suggests that the health problems associated with disruptions to animals’ 24-hour rhythms of activity and rest — which in humans is linked to eating for most of the day or doing shift work — can be corrected by eating all calories within a 10-hour window.

“For many of us, the day begins with a cup of coffee first thing in the morning and ends with a bedtime snack 14 or 15 hours later,” said Satchidananda Panda, Professor at the Salk Institute.

“But restricting food intake to 10 hours a day, and fasting the rest, can lead to better health, regardless of our biological clock,” he added.

The researchers demonstrated that the circadian clocks strikes a balance between sufficient nutrition during the fed state and necessary repair or rejuvenation during fasting.

When this internal clock is disrupted, as when humans do shift work, or when it is compromised due to genetic defects, the balance breaks down and diseases set in.

Health
The researchers demonstrated that the circadian clocks strikes a balance between sufficient nutrition during the fed state and necessary repair or rejuvenation during fasting. Pixabay

For the study, which appeared in the journal Cell Metabolism, the team disabled the genes responsible for maintaining the biological clock in mice, including in the liver, which regulates many metabolic functions.

They then put the mice on one of two high-fat diet regimes: one group had access to food around the clock, the other had access to the same number of calories only during a 10-hour window.

As expected, the group that could eat at any time became obese and developed metabolic diseases.

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But the group that ate the same number of calories within a 10-hour window remained lean and healthy — despite not having an internal “biological clock” and thereby genetically programmed to be morbidly sick.

“Many of us may have one or more disease-causing defective genes that make us feel helpless and destined to be sick. The finding that a good lifestyle can beat the bad effects of defective genes opens new hope to stay healthy,” Panda said. (IANS)

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Light Physical Activity is Good For Stroke Survivors, Says Study

The researchers discovered that, on average, the stroke survivors logged only about seven minutes of moderate-to-vigorous activity per day

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Heart Stroke
Stroke is a major cause of disability in older adults globally. Pixabay

Researchers, including one of Indian-origin, have revealed that stroke survivors who engaged in a lot of light physical activity such as taking leisurely walks or attending to non-strenuous household chores reported fewer physical limitations than their more sedentary peers.

In the findings published in the American Journal of Physical Medicine and Rehabilitation, the research team used accelerometers to measure daily physical activity in 30 stroke survivors for a week, assessing how much the participants moved and how well they performed routine physical tasks.

Stroke is a major cause of disability in older adults globally.

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“Our findings are preliminary but suggest that – in addition to moderate-to-vigorous physical activity — those daily routines that keep us on our feet and physically engaged in lighter tasks also contribute to better physical functioning in stroke survivors,” said study researcher Neha Gothe, Professor at the University of Illinois at Urbana in the US.

For the findings, the research team used two measures of physical ability — the Short Physical Performance Battery, which measures balance, walking speed and lower-limb endurance, and the Late-Life Function and Disability Instrument, which asks participants to report how difficult it is for them to perform daily tasks such as getting in and out of a car or pouring water from a heavy pitcher.

Heart Rate
Researchers, including one of Indian-origin, have revealed that stroke survivors who engaged in a lot of light physical activity such as taking leisurely walks or attending to non-strenuous household chores reported fewer physical limitations than their more sedentary peers. Pixabay

The researchers discovered that, on average, the stroke survivors logged only about seven minutes of moderate-to-vigorous activity per day. “In contrast, they averaged more than three hours of light physical activity each day,” Gothe said.

“This includes things like walking at a leisurely pace, housekeeping, light gardening or other activities that do not cause a person to break a sweat,” she added.

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The amount of moderate-to-vigorous physical activity was the best predictor of participants’ performance on objective measures of physical function, the researchers found. But a person’s self-reported ability to perform daily tasks was much more closely associated with the amount of time they engaged in light physical activity.

“Engaging in light physical activity can be healthy and beneficial, especially for those with chronic health conditions such as stroke,” Gothe noted. (IANS)