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- Guillain-Barre is a normally rare condition that affects the peripheral nervous system, the nerves in arms and legs that are responsible for sensation and movement
- Treatment involves filtering the blood to clean up the immunological factors that attack the peripheral nervous system, causing Guillain-Barre syndrome
- Barre syndrome typically appeared two to six weeks after people showed signs of infection with Zika, including fever, rash, headache and an eye infection called conjunctivitis
Washington, October 9, 2016: Researchers have discovered the strongest evidence yet linking the Zika virus to the paralytic illness Guillain-Barre syndrome. During the height of the viral epidemic the incidence of Guillain-Barre was 100 times the number of cases usually seen.
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Guillain-Barre is a normally rare condition that affects the peripheral nervous system, the nerves in arms and legs that are responsible for sensation and movement. The immune system attacks the fatty myelin coating of the nerves that protect and speed signals from the brain to the limbs.
Zika is in a family of viruses transmitted by mosquitoes called flavivirus, including dengue fever, yellow fever, Japanese encephalitis and chikungunya.
Normally, there are between one and two cases of Guillian-Barre per hundred thousand adults according to Carlos Pardo, a neurologist and pathologist at Johns Hopkins University in Maryland and lead author of a study published this week in the New England Journal of Medicine.
But at the height of the Zika epidemic between January and June in Colombia, where the study was conducted, hospitals were seeing 10 to 15 cases per week.
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Pardo and colleagues from six institutions in the U.S., Central and South America established the first biological evidence connecting Zika to Guillain-Barre.
Investigators recruited 68 patients but because of research limitations were only able to look for evidence of Zika in 42 patients complaining of symptoms of Guillain-Barre syndrome. They underwent a genetics test looking for Zika RNA.
Seventeen – or 40 percent – of patients showed the virus’ genetic footprint.
Pardo’s team also conducted blood and urine tests on each patient. Investigators were able to culture the virus in the urine and found immune system-produced antibodies against Zika in the blood samples. The most positive results were in the urine.
Occurrence of the disease was reported less in the media than microcephaly, another condition that linked to Zika. Microcephaly causes an abnormally small head and brain in newborns of mothers infected with Zika, leaving babies severely disabled.
Pardo says the magnitude of Guillain-Barre was similar to microcephaly.
Pardo says symptoms of Guillain-Barre syndrome typically appeared two to six weeks after people showed signs of infection with Zika, including fever, rash, headache and an eye infection called conjunctivitis.
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Pardo says it’s important to get to patients early because there are treatments that can lessen the severity of Guillain-Barre.
“If we are able to diagnose those patients in an early stage, we are able to provide them with an early treatment… that may prevent those neurological disabilities,” said Pardo.
For now, the Zika epidemic has settled down with the rainy season.
But Pardo is worried what will happen when the weather in the Americas gets warmer and drier at the end of the year.
“Subsequently, there’s going to be a higher risk for Guillian-Barre and obviously maternal infection and higher risk for pregnant mothers to have babies with microcephaly,” said Pardo.
Treatment involves filtering the blood to clean up the immunological factors that attack the peripheral nervous system, causing Guillain-Barre syndrome. (VOA)
Prior to the brutal second wave of the pandemic, Prime Minister Narendra Modi had cautioned civil services probationers against developing the despised "babu mindset". He gave the invaluable piece of advice while addressing civil services probies at the well-known Lal Bahadur Shastri National Academy of Administration in Mussoorie via video-conferencing. He also outlined the keystone mantra of "minimum government and maximum governance".
With the recent collapse of the under-construction flyover in Bandra Kurla Complex which injured 14 labourers, it seems like the Brihanmumbai Municipal Corporation (BMC) has got the PM's keystone mantra all wrong. The recent flyover collapse isn't an isolated incident, in fact, a month ago a similarly bemusing incident took place in the eastern part of the suburbs.
On 1st August 2021, the honourable Chief Minister of Maharashtra Shri. Uddhav Thackeray inaugurated a flyover in the eastern part of the suburbs. In his inaugural speech, he quipped the BMC to smoothen the rough road surface. The BMC swing into action and the surface of the flyover was swiftly re-worked upon. But, instead of smoothening the pre-existing rough surface, the shoddy repair work added to the problem. To top it all off, the BMC added a barrage of speed breakers and rumbler strips on the bridge.
The shoddy repair work combined with a plethora of speed breakers caused long congestions on the Mankhurd-Ghatkopher stretch, ultimately killing the purpose of building the bridge. Moreover, after numerous accidents of motorbikes skidding on the bridge during the rain and the subsequent death of a rider the bridge was closed for traffic.
The construction of the flyover commenced in February 2016 at an approved cost of ₹500 crores. The project was slated to be delivered in January 2019 but was delayed multiple times. The BMC had also made a design change in the flyover by adding a connector to the Deonar dumping ground due to which the construction cost of the flyover was increased to over ₹700 crore. The flyover was expected to bring relief to the traffic on Ghatkopar-Mankhurd Link Road but instead, it added to the existing traffic woes. On a concluding note, the maximum city of Mumbai runs on barely minimum governance, literally.
Keywords: Mumbai, Narendra Modi, Civil Services, Governance.
Along with the undeniable natural beauty, the Kashmir valley has developed a reputation for adventurous activities like trekking, hiking, and river rafting. Kashmir has maintained its charm, allowing us to time-travel into beautiful destinations which make one forget about the stress and worries of life. The hikes in Kashmir offer adventurers to go on a self-discovery trip through nature's lap over the mountains while taking in the breathtaking scenery that surrounds them on their journey. In addition to the hikes, there are many thrilling adventure activities, like rock climbing, rope climbing, etc. Trekking across the region of mountains and lakes will allow you to experience living in the "Paradise on Earth," and you wouldn't want to return to your regular life after that.
The following are some of the finest hiking destinations in Kashmir:
#1: Kashmir Great Lakes Trek: You will be transported to a heavenly and unseen aspect of Kashmir on the Kashmir Great Lakes Trek. In addition to three high-altitude passes and five river valley crossings, this is the only trip in the Himalayas that includes seven alpine lakes, each of which is a stunning shade of green, blue, or turquoise. The extravagance is limitless and breathtakingly stunning every day: infinite blue sky, a larger-than-life backdrop of the Rocky Mountains, colourful meadows overflowing with wildflowers, river crossings are just a few examples of what you will encounter during the trek.
You will be transported to a heavenly and unseen aspect of Kashmir on the Kashmir Great Lakes Trek. | Photo by prayer flags on Unsplash
#2: Sonamarg-Vishansar-Bandipora Trek: The Sonamarg-Vishansar-Bandipora trek is a one-of-a-kind experience that provides a glimpse into Kashmir's undiscovered regions. Sonamarg, famously known as the Meadows of Gold, is the starting point for this fascinating journey that is the perfect experience for anyone looking to get away from the frantic tourist rush. This trek is a fascinating journey that allows nature enthusiasts to bask in the splendour of nature's grandeur. The trek goes over many high mountain passes, some as high as 4000 metres in elevation. The hiking route, in addition to providing breathtaking views of the magnificent Vishansar Lake, provides visitors with the chance to see more than 50 alpine lakes.
Sonamarg, famously known as the Meadows of Gold, is the starting point for this fascinating journey. | Photo by YASER NABI MIR on Unsplash
ALSO READ: Top 10 Beautiful Sights To VIsit In Kashmir
#3: Tral-Narastan-Marsar Trek: The Tral-Narastan-Marsar trek is filled with a range of exciting experiences from beginning to end. The hiking trail passes past a waving saffron field, beautiful meadows, and several streams. The path also crosses the Dachigam National Park, where there is an opportunity to see various animal species. Trekkers may take in spectacular views of the high mountains running parallel to them as they cut and pass through Narastan, a Hindu pilgrimage place.
The Tral-Narastan-Marsar trek is filled with a range of exciting experiences from beginning to end. | Wikimedia Commons
#4: Chhatargul-Mahlish-Gangabal: The journey, which passes through beautiful locations such as Chattargul, Mahlish, Kolsar, and Trunkul, provides a peek into an utterly uninhabited wilderness of Kashmir. There are lakes and meadows adorned with flowers along the route as one trek into the alpine wilderness. Trekkers can also enjoy fishing in the crystal clear lakes, camping, or just seeing towering snow-capped mountains while on their journey.
There are lakes and meadows adorned with flowers along the route as one treks into the alpine wilderness. | Wikimedia Commons
#5: Kolahoi Base Camp Trek: The Kolahoi Base Camp trek in Kashmir has been famous since the early 1900s and has been a goal for many seasoned hikers from across the world. While Srinagar serves as the beginning point for the trip, it is in Aru Valley that the actual hiking begins. The Kolahoi Base Camp Trek is a gentle adventure that is ideal for novices and families with children. The breathtaking sight of the peaks rising into the sky on the horizon of the Pirpanjal and Karakoram ranges is certainly worth capturing. It is considered to be one of the most popular treks in the Kashmir valley.
The Kolahoi Base Camp Trek is a gentle adventure that is ideal for novices and families with children. | Wikimedia Commons
Kashmir's natural splendour, with its beautiful valleys and towering mountains, is really unlike anywhere. Trekking through various valleys and peaks while taking in the scenic beauty is something that always calms the heart and provides us with memories that we will remember for a lifetime.
Keywords: Kashmir, Lakes, Alpine, Hiking, Trekking, Treks, Sonamarg, Gangabal, Kolahoi, Chhatargul, Mahlish, Tral, Narastan, Marsar
The Pitru Paksha starts after the Full Moon day, and this day marks the beginning of the waning phase of the Lunar cycle. This event is roughly of 15-day period, and is of great significance. From this day, rituals like Tarpan or Tarpanam and Shradh are carried out to pay respects to dead relatives and ancestors.
It is believed that from the very first day till the last day, the unhappy souls of the deceased return to the Earth to see their family members. So, in order to ensure that the dead attain Moksha, i.e. to get liberation, family members of these souls quench their thirst and satisfy their hunger by performing the Pind Daan, which includes offering food consisting of cooked rice and black sesame seeds. The literal meaning of Pind Daan is the act of satisfying those who no longer exist physically.
For fifteen days, prayers are offered in temples and rituals are performed to help the souls get free from the cycle of birth, life, and death, and attain salvation.
At the same time, the Pitru Paksha is also an important period for people with Pitru Dosha, which means the curse imposed by the ancestors. Hence, in order to ask forgiveness, people perform Shradh rituals and offer food to the crows, who are considered as living beings that represent the dead. It is believed, if the crow eats the offered food, the ancestors are happy and pleased. But, if the crow doesn't eat the offered food and flies away, the ancestors are not happy.
The event of Pitru Paksha is widely observed by Hindus from all over the world, and they perform prayers and rituals in order to gain their ancestors blessings.