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Experimental Malaria Vaccine found to protect people in early clinical Trial: Study

In a recent clinical trial, an experimental Malaria vaccine has been found that can protect people when administered with antimalarial medication

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London, Feb 16, 2017: When administered together with antimalarial medication, an experimental malaria vaccine has been found to protect people in early clinical trial.

The study involved 67 healthy adult test persons, none of whom previously had malaria.

The best immune response was shown in a group of nine test persons who received the highest dose of the vaccine three times at four-week intervals.

At the end of the trial, all nine of these individuals had 100 per cent protection from the disease, according to the study published in the journal Nature.

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“By vaccinating with a live, fully active pathogen, it seems clear that we were able to set of a very strong immune response,” said study leader Benjamin Mordmueller from German Centre for Infection Research.

“Additionally, all the data we have so far indicate that what we have here is relatively stable, long-lasting protection,” Mordmueller said.

In the group of test persons who demonstrated 100 per cent protection after receiving a high dose three times, Mordmueller said, the protection was reliably still in place after 10 weeks — and remained measurable for even longer.

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The new vaccine showed no adverse effects on the test persons, Mordmueller said.

Malaria parasites are transmitted by the bite of female Anopheles mosquitoes. The Plasmodium falciparum parasite is responsible for most malaria infections and almost all deaths caused by the disease worldwide.

The vaccine, PfSPZ-CVac, developed by Sanaria Inc., of Rockville, Maryland, is administered intravenously to generate an immune response to protect against malaria infection.

The vaccine introduces live Plasmodium falciparum malaria parasites into the bloodstream.

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In this study, conducted at the University of Tubingen in Germany, oral antimalarial medication (chloroquine) was given simultaneously to prevent an actual malarial infection.

The researchers showed that PfSPZ-CVac induced a response from vaccine recipients’ T cells — white blood cells that activate the rest of the immune system — which was proportional to the dosage of the vaccine.

“That protection was probably caused by specific T-lymphocytes and antibody responses to the parasites in the liver,” Professor Peter Kremsner from Institute of Tropical Medicine, University of Tubingen.

The researchers said their next step is to further test the vaccine’s effectiveness over several years in a clinical study in Gabon. (IANS)

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FIFA World Cup 2018: Indian Cuisine becomes the most sought after in Moscow

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Indian cuisine in FIFA World cup
Indian dishes available in Moscow during FIFA World Cup 2018, representational image, wikimedia commons

June 17, 2018:

Restaurateurs Prodyut and Sumana Mukherjee have not only brought Indian cuisine to the ongoing FIFA World Cup 2018 here but also plan to dish out free dinner to countrymen if Argentina wins the trophy on July 15.

Based in Moscow for the last 27 years, Prodyut and Sumana run two Indian eateries, “Talk Of The Town” and “Fusion Plaza”.

You may like to read more on Indian cuisine: Indian ‘masala’, among other condiments spicing up global food palate.

Both restaurants serve popular Indian dishes like butter chicken, kebabs and a varied vegetarian spread.

During the ongoing FIFA World Cup 2018, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

The Mukherjees, hailing from Kolkata, are die-hard fans of Argentina. Despite Albiceleste drawing 1-1 with Iceland in their group opener with Lionel Messi failing to sparkle, they believe Jorge Sampaoli’s team can go the distance.

“I am an Argentina fan. I have booked tickets for a quarterfinal match, a semifinal and of course the final. If Argentina goes on to lift

During the World Cup, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

FIFA World Cup 2018 Russia
FIFA World Cup 2018, Wikimedia Commons.

“We have been waiting for this World Cup. Indians come in large numbers during the World Cup and we wanted these eateries to be a melting point,” he added.

According to Cutting Edge Events, FIFA’s official sales agency in India for the 2018 World Cup, India is amongst the top 10 countries in terms of number of match tickets bought.

Read more about Indian cuisine abroad: Hindoostane Coffee House: London’s First Indian Restaurant.

Prodyut came to Moscow to study engineering and later started working for a pharmaceutical company here before trying his hand in business. Besides running the two restaurants with the help of his wife, he was into the distribution of pharmaceutical products.

“After Russia won the first match of the World Cup, the footfall has gone up considerably. The Indians are also flooding in after the 6-9 p.m. game. That is the time both my restaurants remain full,” Prodyut said.

There are also plans to rope in registered fan clubs of Latin American countries, who will throng the restaurants during matches and then follow it up with after-game parties till the wee hours.

“I did get in touch with some of the fan clubs I had prior idea about. They agreed to come over and celebrate the games at our joints. Those will be gala nights when both eateries will remain open all night for them to enjoy,” Prodyut said.

Watching the World Cup is a dream come true for the couple, Sumana said.

“We want to make the Indians who have come here to witness the spectacle and feel at home too. We always extend a helping hand and since we are from West Bengal, we make special dishes for those who come from Bengal,” she added. (IANS)