Thursday December 13, 2018

Exposure to Pollen During Pregnancy May up The Risk of Asthma in Kids

For the study, the team analysed cord blood collected from hundreds of babies born in Melbourne, Denmark and Germany

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Maternal exposure to pollen ups risk of asthma in babies. Pixabay
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Babies born to mothers who got exposed to pollen during the last trimester may be at increased risk of developing respiratory diseases such as asthma, says a study.

The findings showed that those born during the peak grass pollen season had high immunoglobulin E (IgE) levels in umbilical cord blood — a marker used to predict the development of allergic diseases.

“We know that outdoor pollen exposure during the first couple of months after birth can lead to allergic respiratory diseases and we suspected that exposure during the later stages of pregnancy may also be important,” said lead researcher Bircan Erbas, Associate Professor from La Trobe University in Melbourne, Australia.

“Many studies have shown that babies with high levels of IgE in cord blood can go on to develop allergies later in childhood, but little is known about how these levels are affected by exposure to pollen in utero.”

However, the study published in Environment International, also showed that being pregnant for an entire grass pollen season may have a protective effect on babies.

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Asthma in kids. (IANS)

“We found these babies had lower IgE levels. This was a significant finding and indicates the possible development of a sensitisation barrier,” Erbas said.

Erbas stressed that the study did not suggest that all babies born during high pollen seasons would develop respiratory disease or other allergies.

“The study provides new insight that could help us predict and manage diseases like asthma – which are a significant public health burden.

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“However, it’s important to remember there are a number of factors that can determine who gets asthma or allergies. This is one piece of the puzzle,” she explained

For the study, the team analysed cord blood collected from hundreds of babies born in Melbourne, Denmark and Germany. (IANS)

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First Successful Case Of Womb Transplant in Brazil

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

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Womb Transplant
Medical team hold the first baby born via uterus transplant from a deceased donor at the hospital in Sao Paulo, Brazil. VOA

A woman in Brazil who received a womb transplanted from a deceased donor has given birth to a baby girl in the first successful case of its kind, doctors reported.

The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins, as well as linking arteries, ligaments and vaginal canals.

It comes after 10 previously known cases of uterus transplants from deceased donors – in the United States, the Czech Republic and Turkey – failed to produce a live birth.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams (nearly 6 lbs), the case study said.

Dani Ejzenberg, a doctor at Brazil’s Sao Paulo University hospital who led the research, said the transplant – carried out in September 2016 when the recipient was 32 – shows the technique is feasible and could offer women with uterine infertility access to a larger pool of potential donors.

Womb
. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.. Pixabay

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it.

“The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population,” Ejzenberg said in a statement about the results.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised.

The first baby born after a live donor womb transplant was in Sweden in 2013. Scientists have so far reported a total of 39 procedures of this kind, resulting in 11 live births.

Experts estimate that infertility affects around 10 to 15 percent of couples of reproductive age worldwide. Of this group, around one in 500 women have uterine problems.

Before uterus transplants became possible, the only options to have a child were adoption or surrogacy.

Infants, baby, WOmb
The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins. Pixabay

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

Also Read: Pregnancy is Possible For Survivors of Breast Cancer

Five months after the transplant, Ejzenberg’s team wrote, the uterus showed no signs of rejection, ultrasound scans were normal, and the recipient was having regular menstruation. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.

At seven months and 20 days – when the case study report was submitted to The Lancet – the baby girl was continuing to breastfeed and weighed 7.2 kg (16 lb). (VOA)