Sunday September 22, 2019

Here’s How Fasting Can Improve Your Overall Health

This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans

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Wikimedia commons
Wikimedia commons

Fasting may not be just a religious or political practice. It may actually protect you against age-related diseases and improve your overall health, researchers say.

The study, led by a team from the University of California-Irvine (UCI), found that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against age-related diseases.

The circadian clock operates within the body and its organs as intrinsic time-keeping machinery to preserve homeostasis in response to the changing environment.

And, while food is known to influence clocks in peripheral tissues, it was unclear until now how the lack of food influences clock function and ultimately affects the body.

“We discovered fasting influences the circadian clock and fasting-driven cellular responses, which together work to achieve fasting-specific temporal gene regulation,” said lead author Paolo Sassone-Corsi, Professor of Biological Chemistry at UCI.

“Skeletal muscle, for example, appears to be twice as responsive to fasting as the liver,” Sassone-Corsi added.

Water fasting can be harmful Wikimedia commons
How fasting can improve your overall health. Wikimedia commons

The research, detailed in the Cell Reports journal, was conducted using mice, which were subjected to 24-hour periods of fasting.

While fasting, the mice exhibited a reduction in oxygen consumption (VO2), respiratory exchange ratio (RER), and energy expenditure, all of which were completely abolished by refeeding, which parallels results observed in humans.

“The reorganisation of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression. In other words, fasting is able to essentially reprogram a variety of cellular responses,” Sassone-Corsi said.

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“Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefiting health and protecting against age-associated diseases.”

This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans. (IANS)

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Physicians Happy While Traders in Shock on Ban on E-Cigarettes in India

With the Union Cabinet directing a blanket ban on e-cigarettes in the country, physicians welcomed the step while e-cigarette traders expressed shock and anger

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e-cigarettes, health, union, ban, india
A man exhales while smoking an e-cigarette, Aug. 28, 2019. VOA

With the Union Cabinet directing a blanket ban on e-cigarettes in the country with complete suspension of their manufacturing, import, export, distribution and storage, physicians welcomed the step while e-cigarette traders expressed shock and anger over the decision.

“Although, e-cigarettes are little less lethal then the conventional cigarettes, we cannot shun away the fact that it contains harmful ingredients. These chemicals can potentially affect the lungs and overall health of the individual in the long run,” Rajesh Chawla, Senior Pulmonologist at Indraprastha Apollo Hospital in New Delhi, told IANS.

Industry body TRENDS which represents importers, distributors and marketers of ENDS, or Electronic Nicotine Delivery Systems in India, termed the decision to ban e-cigarettes “ironic and erratic”.

“This ban on e-cigarettes on the basis of ‘selective sourcing of scientific and medical opinion’ and without holding a single stakeholder meeting is nothing short of a complete murder of democratic norms,” said Praveen Rikhy, Convenor, TRENDS (Trade Representatives of ENDS).

“All our representations sharing best practices from other countries – 70 developed countries have allowed regulated sale of e-cigarettes, have been completely ignored. We will now initiate a formal campaign to help MPs understand the issue, clarify misapprehensions and misinformation spread by lobby groups and support the farmer groups who see the growth of the e-cigarette sector as a global market opportunity for nicotine,” Rikhy said.

e-cigarettes, health, union, ban, india
The Donald Trump administration on September 12 said that it plans to ban the sale of non-tobacco-flavoured e-cigarettes in the US following six deaths. Pixabay

While e-cigarettes have been marketed as a way for adults to quit conventional smoking, a recent outbreak of lung illness associated with use of vaping products in the US has raised concerns about the safety of these products.

The Donald Trump administration on September 12 said that it plans to ban the sale of non-tobacco-flavoured e-cigarettes in the US following six deaths linked to vaping.

Health authorities have documented a total of 450 cases involving e-cigarettes, according to the US Centers for Disease Control and Prevention (CDC), which issued a health warning against vaping.

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“I entirely support the idea of a ban on e-cigarettes; it is a step in the right direction,” Manoj Luthra, CEO, Jaypee Hospital in Noida, told IANS.

“E-cigarettes have been projected as a means to help people to quit smoking tobacco and also being non-polluting. However, these have their own health hazards and are addictive as well. These contain nicotine and other chemical vapours which will certainly have ill effects on the heart and lung and other organs as well,” he said. (IANS)