Tuesday, April 20, 2021
Home Life Style Health & Fitness Fat Cells May Influence How Body Reacts To Heart Failure

Fat Cells May Influence How Body Reacts To Heart Failure

A common treatment for heart failure is beta-blocker drugs, which are designed to block the effects of stress hormones on the heart

Limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients, say, researchers. The study, published in the American Journal of Physiology, found that mice with heart failure that were treated with a drug blocking the release of fat into the bloodstream from fat cells saw less inflammation in the heart and throughout the body, and had better outcomes than a control group.

“Many people believe that, by definition, heart failure is only a condition of the heart. But it’s much broader and multiple organs are affected by it,” said researcher Jason Dyck from the University of Alberta in Canada.

Follow NewsGram on Twitter to stay updated about the World news.

“What we’ve shown in mice is that if you can target fat cells with a drug and limit their ability to release stored fat during heart failure, you can protect the heart and improve cardiac function,” Dyck added.

fat cells
Many people believe that, by definition, heart failure is only a condition of the heart. IANS

According to the researcher, during times of stress, such as heart failure, the body releases stress hormones, such as epinephrine and norepinephrine, to help the heart compensate. But because the heart can’t function any better — and is in fact damaged further by being forced to pump faster — the body releases more stress hormones and the process cascades, with heart function continuing to decline.

ALSO READ: COVID Increases Death Risk In Patients With Acute Heart Failure

This is why a common treatment for heart failure is beta-blocker drugs, which are designed to block the effects of stress hormones on the heart, the team said. The release of stress hormones also triggers the release of fat from its storage deposits in fat cells into the bloodstream to provide extra energy to the body, a process called lipolysis.

The team found that during heart failure, the fat cells in mice were also becoming inflamed throughout the body, mobilizing and releasing fat faster than normal and causing inflammation in the heart and rest of the body. This inflammation put additional stress on the heart, adding to the cascade effect, increasing damage, and reducing heart function, the researchers said. (IANS/SP)

STAY CONNECTED

19,517FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

More Urban Indians Suffer Payment App Frauds, Card Frauds: Report

More urban Indians are facing payment app frauds (24 percent), identity thefts (20 percent), and payment card frauds (18 percent) than ever before during...

Rapprochement Between Russia And The US?

The recent announcement by the White House sources that US President Joe Biden has proposed that he and his Russian counterpart Vladimir Putin hold...

Recognize And Seize Your Serendipitous Moments: Neil J. Farber

Archimedes' discovery of the relationship of weight, volume, and density of materials, Alexander Fleming's discovery of penicillin, Samuel Morse devising the Morse code, Alexander...

Sweat Sensor Alerts Doctors And Patients To Impending Cytokine Storm In Real Time

Scientists have developed a sweat sensor that acts as an early warning system for a looming cytokine storm -- a surge of pro-inflammatory immune...

Gender-Affirming Hormone Therapy Associated With High BP Risk

Gender-affirming hormone therapy (GAHT) was associated with blood pressure changes in both transgender men and women, according to new research. Although doctors have prescribed...

Nanking Massacre: The Holocaust

By- Khushi Bisht The Nanking Massacre, also known as the Rape of Nanking, was one of the worst massacres committed during the Sino-Japanese war that...

‘Child Of Two Worlds’ Featuring The Protagonists And Immortal Lovers

Turkey-based author Ann D'Silva has launched her new book "Child of Two Worlds", which is second in the fictional 'Sand and Sea' series, which...

Now Transfer Posts And Notes To Google Docs And WordPress Directly

Facebook on Monday introducing two new data portability types that will help users directly transfer their posts and notes to Google Documents, Blogger, and...

Recent Comments