Wednesday November 20, 2019

Finally The Cause Of Depression Among Diabetes Patients Discovered

The research showed that higher levels of galectin-3 -- an inflammatory protein -- is the culprit.

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Diabetes
Representational image. Pixabay

Increased levels of a protein inflammation in the body may be the reason behind depression — a mental health disorder characterised by persistently depressed mood or loss of interest in activities — among people with Type-1 diabetes, according to researchers.

It is well established that people with both Type-1 and Type-2 diabetes have an increased risk of developing depression, but the causes remain poorly understood.

The research showed that higher levels of galectin-3 — an inflammatory protein — is the culprit.

Galectin-3 is a key protein involved in promoting inflammatory immune system responses that are needed to repair tissue damage throughout the body, in response to injury or disease.

Depression
Depression, flickr

According to the researchers, galectin-3 — also linked with Alzheimer’s and cardiovascular diseases — may be useful for diagnosis of depression or maybe a new target for treating depression associated with Type-1 diabetes, which could lead to better patient care.

“We found that people with Type-1 diabetes and depression had higher galectin-3 levels, yet no other diabetes-related metabolic changes could account for these elevated levels,” said Eva Olga Melin from Lund University, Sweden.

The study, published in the journal Endocrine Connections, analysed data on measurements of galectin-3 levels in 283 people, aged between 18-59 years, with Type-1 diabetes for a year.

The results showed that both men and women with Type-1 diabetes and depression also had significantly higher galectin-3 levels.

Also read: Wife’s BMI Mens risk of developing diabetes

“…these findings suggest that further investigating the role of galectin-3 could lead to improved diagnosis and maybe better treatment outcomes for patients in the future,” Melin said.(IANS)

Next Story

40% Parents Struggle to see Depression Signs in Kids: Study

Most parents also believe schools should play a role in identifying potential depression, with seven in 10 supporting depression screening starting in middle school, the study said

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In boys it is previous depressive symptoms which determine subsequent suicidal ideation. Pixabay

Telling the difference between a teen’s normal ups and downs or something bigger is among the top challenges parents face while identifying depression among the youth, says a new study.

Forty per cent of parents struggle to differentiate between normal mood swings and signs of depression, while 30 per cent are tricked as their child hides his/her feelings well, according to a new national poll in the US.

The C.S. Mott Children’s Hospital National Poll on Children’s Health at the University of Michigan, is based on responses from 819 parents with at least one child in middle school, junior high, or high school.

“In many families, the preteen and teen years bring dramatic changes both in youth behaviour and in the dynamic between parents and children,” said poll co-director Sarah Clark.

“These transitions can make it particularly challenging to get a read on children’s emotional state and whether there is possible depression,” Clark added.

According to the researchers, some parents might be overestimating their ability to recognise depression in the mood and behaviour of their own child.

An overconfident parent may fail to pick up on the subtle signals that something is amiss.

suicide, world, deaths, study
Depression is among the leading causes of disability in the U.S. and is being closely monitored by health authorities amid rising suicides nationwide. Pixabay

The poll also suggests that the topic of depression is all too familiar for middle and high school students.

One in four parents say their child knows a peer or classmate with depression, and one in 10 say their child knows a peer or classmate who has died by suicide.

This level of familiarity with depression and suicide is consistent with recent statistics showing a dramatic increase in suicide among US youth over the past decade.

Rising rates of suicide highlight the importance of recognising depression in youth.

Also Read: Study Finds No Link Between Fish Oil and Prostrate Cancer

Compared to the ratings of their own ability, parents polled were also less confident that their preteens or teens would recognise depression in themselves.

“Parents should stay vigilant on spotting any signs of potential depression in kids, which may vary from sadness and isolation to anger, irritability and acting out,” said Clark.

Most parents also believe schools should play a role in identifying potential depression, with seven in 10 supporting depression screening starting in middle school, the study said. (IANS)