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Barbara Bush, the matriarch of a Republican political dynasty and a former First Lady who elevated the cause of literacy, has died at the age of 92, media reports said.
“A former First Lady of the United States of America and relentless proponent of family literacy, Barbara Pierce Bush passed away on Tuesday at the age of 92,” family spokesman Jim McGrath said in a statement.
Barbara Bush is survived by her husband former President George H.W. Bush; sons George W., Neil, Marvin and Jeb; daughter, Dorothy Bush Koch; and 17 grandchildren.
On Sunday, her husband’s office issued a statement saying that after consulting the family and her doctors, Barbara Bush had “decided not to seek additional medical treatment and will instead focus on comfort care”, reports The New York Times.
The Bushes had celebrated their 73rd wedding anniversary in January, making them the longest-married couple in presidential history.
Only the second woman in American history to have had a husband and a son elected President (Abigail Adams was the first), Barbara Bush was seen as a plainspoken public figure who was instantly recognisable with her signature white hair and pearl necklaces and earrings, reports CNN.
She became a major political figure as her husband rose to become first a Vice President (January 20, 1981 – January 20, 1989) and then the 41st US President (January 20, 1989 – January 20, 1993).
He left office in 1993 after losing a re-election bid to Bill Clinton.
After they left the White House, she was a potent spokeswoman for two of her sons — George W. and Jeb — as they campaigned for office.
The mother of six children — one of whom, a daughter, Robin, died as a child from leukemia — Barbara Bush raised her fast-growing family in the 1950s and ’60s amid the post-war boom of Texas and the whirl of politics that consumed her husband.
Barbara Pierce was born on June 8, 1925, in New York and raised in the upscale town of Rye, CNN reported.
She attended a prestigious boarding school in South Carolina, where she met her future husband at a school dance when she was only 16 and he was a year older.
A year and a half and countless love letters later, the two were engaged just before George H. W. Bush enlisted in the Navy and went off to fight in the World War II.
Barbara Bush adopted literacy as a cause, raising awareness and eventually launching the non-profit Barbara Bush Foundation for Family Literacy.
After George H.W. Bush’s presidency, he and Barbara raised more than $1 billion for literacy and cancer charities.
A writer, her books include an autobiography and one about post-White House life. Her children’s book about their dog, Millie, and her puppies written during her White House years was a bestseller.
In 2001, when George W. Bush took office, Barbara Bush became the only woman in American history to live to see her husband and son elected president. IANS
Canadian researchers have discovered an overlooked gene that plays a major role in the development of antibodies, which help the immune system recognize and fight viruses including SARS-CoV-2, bacteria and other causes of infectious disease. The gene -- FAM72A -- facilitates production of high-quality antibodies by enabling the effect of an enzyme called AID (for Activation-Induced Deaminase), the researchers showed.
Immunologists have known for two decades that AID is essential to produce antibodies capable of clearing infections, but the full mechanism of its effect has remained unknown. "Our findings answer the long-standing question of how AID does its work," said Alberto Martin, a professor of immunology at the University of Toronto's Temerty Faculty of Medicine. "FAM72A helps AID to promote mutations in antibody genes that are essential for the development of effective antibodies," he added.
Genetic mutations that lead to lasting changes in DNA occur through a process called mutagenesis. | Pixabay
Genetic mutations that lead to lasting changes in DNA occur through a process called mutagenesis. In the context of antibody development, mutagenesis unfolds largely through the AID-driven mechanisms called somatic hypermutation and class switch recombination -- both of which help antibodies gain the diversity and potency they need to counter a wide range of pathogens.
The results published in the journal Nature will help researchers better understand antibody development broadly, but they also have implications for cancer. Uncontrolled mutagenesis in B cells that produce antibodies is linked to B cell lymphoma, and FAM72A is present at very high levels in other cancers such as gastrointestinal, breast, lung, liver and ovarian cancers.
"Our data show that high levels of FAM72A promote mutations in antibody genes, so increased levels of FAM72A could spur cancer development, progression or drug resistance by increasing mutagenesis,a Martin said. Martin's team is now exploring those possibilities. Intriguingly, unlike other mammals, humans have four gene versions of FAM72A and their roles in cancer and antibody production are still unknown. (IANS/ MBI)
Keywords: researchers, cancer, mutagenesis, antibody, development, antibodies, canada, COVID
Mahanadi Coalfields Limited (MCL), a subsidiary of Coal India will set up a 50 megawatt (MW) solar power plant in Odisha's Sambalpur at a total cost of Rs 301.92 crore, moving steadily towards its goal to achieve carbon neutrality by 2024. MCL has placed a turnkey order to set-up a 50 MW solar power plant with a Chennai-based firm M/s Hild Energy Ltd, which will establish this green energy project within a timeline of 10 months, the MCL said in a statement on Saturday.
This solar plant would cater to the captive power requirement of MCL. The Central PSU had successfully set-up a 2MW solar power plant in Sambalpur in 2014. The company said it has pledged a target of installing 182 MW of solar power by 2024 in order to become a net zero energy company, aligning itself to use cleaner forms of energy for coal production.
The company said it has pledged a target of installing 182 MW of solar power by 2024. | Photo by Mariana Proença on Unsplash
This 50 MW solar power project will reduce CO2 emission by 91,020 tonnes per annum and carbon offsets of around 24,824 tonnes per annum, claimed the MCL. MCL is the leading production subsidiary of Coal India, having mining operations in Angul, Jharsuguda and Sundargarh districts of Odisha. Having achieved the highest ever capital expenditure of Rs 2,419 crore in the financial year 2020-21, the company has coal production and dispatch targets of 163 million tonnes and 182 million tonnes, respectively.
MCL was the coal mining company to introduce environment-friendly surface miner technology, which contributes over 95 per cent in coal production. As another environment-friendly initiative, the company has successfully introduced vertical rippers for blast-less over-burden removal in Hingula and Kaniha opencast projects. (IANS/ MBI)
Keywords: solar plant, carbon neutrality, Odisha, Sambalpur, Coal India, subsidiary, Mahanadi Coalfields Limited, solar energy
As the nation celebrated the 114th birth anniversary of his father - renowned poet Harivansh Rai Bachchan - megastar Amitabh Bachchan remembered his dad as he penned a heartfelt note for him. The actor took to his blog where he poured his heart out and also shared an unseen photo with his father. The image in question is from Big B's wedding in 1973, where the two are caught in a sweet moment as they look at each other.
Amitabh Bachchan wrote on his blog,
"My Father , my all .. November 27th his birth in the year 1907 .. Which makes it his 114th Anniversary .. He is in the heavens, with my Mother and they celebrate .. as do we , in thought word and deed .. (sic). But first."
He then posted the picture followed by elaborate paragraphs. The megastar wrote,
"Those rare moments when one would find himself rushing against the winds to prevent the distance between us and to close it down as soon as it can be. The day of my wedding and his expression of fulfilment to not just be in congratulation but instead to be in the face of a belief, a chime, an ultimate season of love and great passion, of the quarries of the fears and conditionings of these deprived gym routines kart ..(sic)". "This could have been unknown for long facilitating years, to give not expected versions and lastly large scale informations of the insides ; but as time passed by, as does now , they explained purposely, the values of education and similarity .. Be in peace and love .. (sic)",
the veteran actor concluded his note. (IANS/ MBI)
Keywords: Amitabh Bachchan, Harivansh Rai Bachchan, actor, blog, birth anniversary, 114th birthday