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Formula made from Cow’s milk may reduce the risk of diabetes

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Formula made from Cow's milk may reduce the risk of diabetes
Formula made from Cow's milk may reduce the risk of diabetes. IANS
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New York, Jan 3, 2018: Drinking formula made from cow’s milk may not put babies at higher risk of developing Type 1 diabetes, the first large international trial showed.

Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin.

Previous studies have reported that early exposure to complex foreign proteins, such as cow’s milk proteins, may increase the risk of Type 1 diabetes in young children with genetic risk for the condition.

For the new study, the team led by University of Pittsburgh Medical Centre, examined 2,159 infants from 15 countries with genetic risk for Type 1 diabetes to find out whether delaying the exposure to complex foreign proteins such as cow’s milk proteins would decrease the risk of diabetes.

After breastfeeding, infants were either weaned to a special formula (extensively hydrolysed casein formula), with the cow’s milk proteins split into small peptides (small pieces of the protein), or a regular cow’s milk-based formula with intact cow’s milk proteins.

Infants were fed the study formula for at least two months until the age of six to eight months and at the same time were given no cow’s milk proteins from any other food sources and were followed for over 10 years.

The findings, published in the Journal of the American Medical Association, revealed that no association was found between children fed formula with whole-milk proteins or those with the proteins broken down.

“The study puts to rest the controversy regarding the potential role of cow’s milk formula in the development of Type 1 diabetes,” said Dorothy Becker, Professor at the varsity.

The study also showed that “there is no evidence to revise the current dietary recommendations for infants at high risk for Type 1 diabetes,” Becker noted. (IANS)

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TB Vaccine May Help to Control Type-1 Diabetes, Says Study

Type - 1 diabetes is a chronic condition in which the pancreas produce little or no insulin

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Previous findings from animal experiments also show a significant connection between restrictive lung diseases and diabetes mellitus.
Previous findings from animal experiments also show a significant connection between restrictive lung diseases and diabetes mellitus.(IANS)

A vaccine primarily used for treating tuberculosis (TB) may be effective in reducing high blood sugar among people with Type – 1 diabetes, results from a clinical trial has revealed.

Type – 1 diabetes is a chronic condition in which the pancreas produce little or no insulin.

The findings showed that, three years after receiving two administrations of the Bacillus Calmette-Guerin (BCG) vaccine four weeks apart, people with longstanding Type-1 diabetes showed an improvement in HbA1c — Aglycated haemoglobin — measured to test the overall sugar levels to near normal levels.

“This is clinical validation of the potential to stably lower blood sugars to near normal levels with a safe vaccine, even in patients with longstanding disease,” said Denise Faustman, director of the Massachusetts General Hospital Immunobiology Laboratory, US.

Representational image.
Representational image. Pixabay

The study, published in the journal npj Vaccine, also reported that the effects of BCG vaccine on blood sugar control appear to depend on a totally novel metabolic mechanism that increases cellular consumption of glucose.

The team analysed data from 282 human study participants — 52 with Type-1 diabetes who participated in the BCG clinical trials and 230 who contributed blood samples for mechanistic studies.

The results showed that the HbA1c levels of those receiving BCG had dropped by more than 10 per cent in three years after treatment and by more than 18 per cent in four years.

Also Read: Study: Plant-based Diets Can Help Diabetes Patients

The study showed that BCG vaccination induces epigenetic reprogramming at the chromatin architecture level and functional alterations indicative of a permanent change in immunity.

Thus, the clinical effects and the proposed mechanism add to the emerging consensus that the BCG vaccine can have a lasting and valuable impact on the immune system, the researchers said. (IANS)

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