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A new drug can reduce Alcohol addiction in teenagers. Pixabay
  • Researchers have found a new drug that may eventually help to reduce alcohol addiction in adults who used to binge during their adolescent years.

A new drug found which can reduce Alcohol addiction in teenagers

“During our teen years, the brain is still in a relatively immature state. Binge drinking worsens this situation, as alcohol undermines the normal developmental processes that affect how our brain matures,” said lead author Jon Jacobsen, a Ph.D. student at the University of Adelaide, Australia.

“Therefore, when an adolescent who has been binge drinking becomes an adult, they’re often left with an immature brain, which assists in the development of alcohol dependence,” Jacobsen added.


For the study, published in the Journal Neuropharmacology, researchers observed that adolescent mice involved in binge drinking behavior developed an increased sensitivity to alcohol as adults and engaged in further binge drinking.

The researchers were able to prevent some of these detrimental behaviors observed in adulthood, by giving mice a drug that blocks a specific response from the immune system in the brain.

The drug is (+)-Naltrexone, known to block the immune receptor Toll-like receptor 4 (TLR4).

“This drug effectively switched off the impulse in mice to binge drink. The mice were given this drug still sought out alcohol, but their level of drinking was greatly reduced,” says senior author Professor Mark Hutchinson, Director of the ARC Centre of Excellence for Nanoscale BioPhotonics at the University of Adelaide.

“We’re excited by the finding that we can potentially block binge drinking in an adult after they have experienced such behavior during adolescence, by stopping the activation of the brain’s immune system. It’s the first time this has been shown and gives us hope that our work has implications for the eventual treatment of alcohol addiction in adults,” Hutchinson noted.(IANS)


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Khadi is no longer a dull, drab fabric meant only for politicians' wardrobes.

Khadi is no longer a dull, drab fabric meant only for politicians' wardrobes. A fashion show organised by the Khadi Gramodyog Board as part of the Azadi Ka Amrit Mahotsav to mark the 75th year of India's Independence showcased the use of Khadi in traditional, as well as, contemporary and festive wear. From lehengas in resplendent Khadi silk to western clothes and casual wear, the models on Thursday night displayed new facts of the fabric.

Several well-known Indian designers including Ritu Beri, Farah Ansari, Rina Dhaka, Asma Husain, Aditi Rastogi and Himmat Singh showcased their designs. Gaurav Gaur directed the fashion show with clothes like lehengas, kurtis, kurta pajamas and partywear.

Lucknow's chikankari and silk artisans also participated in the event. A wedding collection in Khadi was the highlight of the show. "The show was based on the concept 'Khadi for nation, Khadi for fashion' and the fabric for all costumes was provided by Khadi Gramodyog Board," said a spokesman. (IANS/ MBI)


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Pat Gelsinger, CEO - Intel

Intel saw its stock tumbling by more than 8 percent after the chipmaker said the industry-wide component shortage affected its PC chip business during the third quarter (Q3). Intel CEO Pat Gelsinger told CNBC late on Thursday that he didn't expect the semiconductor shortage to end until 2023. "We're in the worst of it now, every quarter, next year we'll get incrementally better, but they're not going to have supply-demand balance until 2023," Gelsinger was quoted as saying.


The company delivered its Q3 results with revenue up 5 percent (year-over-year) driven by strong demand in its DCG and IoTG businesses, despite the highly constrained industry-wide supply environment. "Q3 revenue was $18.1 billion slightly below our guide due to shipping and supply constraints that impacted our businesses," George S. Davis, Chief Financial Officer, said in a statement. He also announced plans to retire from Intel in May 2022. In the third quarter, the company generated $9.9 billion in cash from operations and paid dividends of $1.4 billion.

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Micro-blogging site Twitter has announced that its audio chatroom Spaces is now open to anyone who wants to host.

Micro-blogging site Twitter has announced that its audio chatroom Spaces is now open to anyone who wants to host. The Spaces team in a tweet said that the users on both Android and iOS will now be able to host Spaces. "The time has arrived -- we're now rolling out the ability for everyone on iOS and Android to host a Space," the firm said in a tweet.

Earlier this year, the company had limited access to hosting Spaces to accounts with at least 600 followers, saying that it found these accounts would be more likely to have a good experience due to the existing audience. Twitter recently announced a new accelerator programme for creators on its audio conversation platform Spaces, to "discover and reward" around 150 creators with technical, financial and marketing support.

The 'Twitter Spaces Spark' programme is a three-month accelerator initiative. Those selected will get a stipend of $2,500 per month, $500 in monthly ad credits to spend promoting their Spaces on Twitter and early access to new Twitter features. They will also get support from Twitter's official social media handles, and "opportunities for prioritised in-app discoverability for well-performing Spaces".

Twitter has also announced plans to roll out paid Ticketed Spaces for iOS users where some hosts on its live audio feature can now sell access to Ticketed Spaces. Twitter had previously said that it will take a 3 per cent cut of creators' earnings from Ticketed Spaces. (IANS/ MBI)


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