Wednesday June 26, 2019

Researchers found a new Drug to Reduce Alcohol Addiction in Teenagers

The drug is (+)-Naltrexone can reduce the drinking habit in teenagers.

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A new drug can reduce Alcohol addiction in teenagers
A new drug can reduce Alcohol addiction in teenagers. Pixabay
  • Researchers have found a new drug that may eventually help to reduce alcohol addiction in adults who used to binge during their adolescent years.

A new drug found which can reduce Alcohol addiction in teenagers

“During our teen years, the brain is still in a relatively immature state. Binge drinking worsens this situation, as alcohol undermines the normal developmental processes that affect how our brain matures,” said lead author Jon Jacobsen, a Ph.D. student at the University of Adelaide, Australia.

“Therefore, when an adolescent who has been binge drinking becomes an adult, they’re often left with an immature brain, which assists in the development of alcohol dependence,” Jacobsen added.

For the study, published in the Journal Neuropharmacology, researchers observed that adolescent mice involved in binge drinking behavior developed an increased sensitivity to alcohol as adults and engaged in further binge drinking.

The researchers were able to prevent some of these detrimental behaviors observed in adulthood, by giving mice a drug that blocks a specific response from the immune system in the brain.

The drug is (+)-Naltrexone, known to block the immune receptor Toll-like receptor 4 (TLR4).

“This drug effectively switched off the impulse in mice to binge drink. The mice were given this drug still sought out alcohol, but their level of drinking was greatly reduced,” says senior author Professor Mark Hutchinson, Director of the ARC Centre of Excellence for Nanoscale BioPhotonics at the University of Adelaide.

“We’re excited by the finding that we can potentially block binge drinking in an adult after they have experienced such behavior during adolescence, by stopping the activation of the brain’s immune system. It’s the first time this has been shown and gives us hope that our work has implications for the eventual treatment of alcohol addiction in adults,” Hutchinson noted.(IANS)

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US to Work with Australia, Canada to Cut Reliance on Chinese Minerals

Over 80 percent of the global supply chain of rare earth elements is controlled by one country

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US, Australia, Canada
FILE - Samples of rare earth minerals (L-R): Cerium oxide, Bastnasite, Neodymium oxide and Lanthanum carbonate are on display during a tour of Molycorp's Mountain Pass Rare Earth facility in Mountain Pass, California. VOA

The United States will team up with Canada and Australia to help countries around the world develop their reserves of minerals like lithium, copper and cobalt, the State Department said on Tuesday, part of a multi-pronged strategy to reduce global reliance on China for materials crucial to high-tech industries.

Washington grew more concerned recently about its dependence on mineral imports after Beijing suggested using them as leverage in the trade war between the world’s largest economic powers.

This would interrupt the manufacture of a wide range of consumer, industrial and military goods, including mobile phones, electric vehicles, batteries, and fighter jets.

“Over 80 percent of the global supply chain of rare earth elements — is controlled by one country,” the State Department said in a fact sheet outlining the effort, which it has dubbed the Energy Resource Governance Initiative. “Reliance on any one source increases the risk of supply disruptions.”

US, Australia, Canada
The United States will team up with Canada and Australia to help countries around the world. VOA

Under the plan, the United States will share mining expertise with other countries to help them discover and develop their resources, and advise on management and governance frameworks to help ensure their industries are attractive to international investors.

Doing so will help to ensure global supply for the minerals can meet world demand, which is projected to surge alongside the growing take-up in high-technology goods. “Demand for critical energy minerals could increase almost 1,000% by 2050,” according to the fact sheet.

Frank Fannon, the U.S. assistant secretary of state for energy resources, said in an interview that tensions with China show the United States should be producing more rare earth minerals and help others ensure a secure supply. “We need to do more and we are not alone in this,” Fannon said.

Canada and Australia, two major mining countries, were partnering in the effort and other allies could join later, a U.S. official said.

Also Read- In Hot Water? Warming Oceans may Reduce Sea Life by 17%,Says Study

Canada’s Ambassador to the United States, David MacNaughton, said Canadian officials have met with the State Department several times to discuss critical minerals and environmental issues around global mining and he looks forward to advancing the initiative.

Representatives of Australia did not immediately respond to a request for comment.

The plan was first reported on Tuesday morning by the Financial Times.

The plan comes a week after the U.S. Commerce Department recommended urgent steps to boost U.S. domestic production of “critical minerals,” including by providing low-interest loans to mining companies and requiring defense companies to “buy American.”

US, Australia, Canada
Washington grew more concerned recently about its dependence on mineral imports. Pixabay

The Commerce report also recommended that U.S. agencies review areas that are currently protected from development and assess whether those restrictions should be lifted or reduced to allow for critical minerals development. (VOA)