Sunday November 17, 2019

Study reveals, Frequent Drinking Can Be More Harmful Than Binges

For the study, published in the journal EP Europace, researchers examined the relative importance of frequent drinking versus binge drinking for new-onset atrial fibrillation

0
//
Drinking
Researchers examined the relative importance of Frequent Drinking versus Binge Drinking for new-onset atrial fibrillation. Pixabay

Alcohol lovers, take a note. Drinking small amounts of alcohol frequently is linked with a higher likelihood of atrial fibrillation than binge drinking, says a new study.

Atrial fibrillation is the most common heart rhythm disorder and raises the risk of stroke by five-fold. Symptoms include palpitations, racing or irregular pulse, shortness of breath, tiredness, chest pain and dizziness.

“Our study suggests that drinking less often may also be important to protect against atrial fibrillation,” said study author Jong-Il Choi, from Korea University College in South Korea.

For the study, published in the journal EP Europace, researchers examined the relative importance of frequent drinking versus binge drinking for new-onset atrial fibrillation.

The analysis included 9,776,956 individuals without atrial fibrillation who underwent a national health check-up in 2009 which included a questionnaire about alcohol consumption.

Drinking
The number of Frequent Drinking sessions is related to atrial fibrillation onset regardless of age and sex. Pixabay

Participants were followed-up until 2017 for the occurrence of atrial fibrillation.

The number of drinking sessions per week was the strongest risk factor for new-onset atrial fibrillation.

Compared with drinking twice per week (reference group), drinking every day was the riskiest, with a hazard ratio (HR) of 1.412, while drinking once a week was the least risky (HR 0.933).

Binge drinking did not show any clear link with new-onset atrial fibrillation.

“Our study suggests that frequent drinking is more dangerous than infrequent binge drinking with regard to atrial fibrillation,” Choi said.

The number of drinking sessions was related to atrial fibrillation onset regardless of age and sex.

Repeated episodes of atrial fibrillation triggered by alcohol may lead to overt disease, the research notes.

Drinking
Drinking small amounts of alcohol frequently is linked with a higher likelihood of atrial fibrillation than binge drinking. Pixabay

In addition, drinking can provoke sleep disturbance which is a known risk factor for atrial fibrillation.

There was a two per cent increase in the risk of new-onset atrial fibrillation for each gram of alcohol consumed per week.

ALSO READ: ASUS Unveils its Innovative Dual Screen Laptop Series in India

Compared to mild drinkers, those who drank no alcohol, moderate, or high amounts had 8.6 per cent, 7.7 per cent, and 21.5 per cent elevated risks, respectively, the study said. (IANS)

Next Story

Immune Cells Become Active and Repair Brain While Sleep: Study

For the findings, researchers conducted the study on mice

0
Sleep
Study suggests that the enhanced remodeling of neural circuits and repair of lesions during Sleep may be mediated in part by the ability of microglia to dynamically interact with the Brain. Pixabay

Researchers have found that immune cells called microglia, which play an important role in reorganising the connections between nerve cells, fighting infections, and repairing damage, are also primarily active while we sleep.

Microglia serve as the brain’s first responders, patrolling the brain and spinal cord and springing into action to stamp out infections or gobble up debris from dead cell tissue.

“This research shows that the signals in our brain that modulate the sleep and awake state also act as a switch that turns the immune system off and on,” said study lead author Ania Majewska, Professor at University of Rochester in the US.

In previous studies, Majewska’s lab has shown how microglia interact with synapses, the juncture where the axons of one neuron connects and communicates with its neighbours.

The microglia help maintain the health and function of the synapses and prune connections between nerve cells when they are no longer necessary for brain function.

For the findings, researchers conducted the study on mice.

The current study points to the role of norepinephrine, a neurotransmitter that signals arousal and stress in the central nervous system.

This chemical is present in low levels in the brain while we sleep, but when production ramps up it arouses our nerve cells, causing us to wake up and become alert.

The study showed that norepinephrine also acts on a specific receptor, the beta2 adrenergic receptor, which is expressed at high levels in microglia.

When this chemical is present in the brain, the microglia slip into a sort of hibernation.

Sleep
Researchers have found that immune cells called microglia, which play an important role in reorganising the connections between nerve cells, fighting infections, and repairing damage, are also primarily active while we Sleep and affects Brain. Pixabay

The study, which employed an advanced imaging technology that allows researchers to observe activity in the living brain, showed that when mice were exposed to high levels of norepinephrine, the microglia became inactive and were unable to respond to local injuries and pulled back from their role in rewiring brain networks.

“This work suggests that the enhanced remodeling of neural circuits and repair of lesions during sleep may be mediated in part by the ability of microglia to dynamically interact with the brain,” said study first author Rianne Stowell.

ALSO READ: Scientists Link ‘Brain Fog’ to Body Illness

“Altogether, this research also shows that microglia are exquisitely sensitive to signals that modulate brain function and that microglial dynamics and functions are modulated by the behavioural state of the animal,” Stowell said.

The study was published in the journal Nature Neuroscience. (IANS)