Sunday December 15, 2019

Daily Consumption of Garlic, Onion Reduces Risk of Colon Cancer

Previous studies have found that allium vegetables have nutrients and bioactive compounds that can cut the risk of cancer, particularly cancers of the gastrointestinal tract

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Hearts diseases
Garlic is also known as the king of heart-healthy herbs, Pixabay

Consuming 50 grams of allium vegetables, which include garlic, leeks, and onions, daily can potentially reduce the risk of getting colorectal cancer, finds a study.

The study, published in the Asia Pacific Journal of Clinical Oncology, showed that the odds of having colorectal cancer was 79 per cent lower in adults who consumed high amounts of allium vegetables compared with those who consumed low amounts.

“The greater the amount of allium vegetables, the better the protection,” said Zhi Li, from the First Hospital of China Medical University.

“In general, the present findings shed light on the primary prevention of colorectal cancer through lifestyle intervention, which deserves further in-depth explorations,”Li added.

For the study, 833 patients of colorectal cancer were matched to 833 healthy controls by age, sex and residence area.

Cancer
Cancer Ribbon. Pixabay

Demographic and dietary information were collected via face-to-face interviews using a validated food frequency questionnaire.

However, the association of garlic intake with cancer risk was not significant among those with distal colon cancer, the Xinhua reported.

According to the study, the health benefits can be observed when one eats about 16 kg of allium vegetables every year or 50 grams every day.

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The researchers also pointed out that cooking method can affect the nutritional value of allium vegetables. For instance, crushing fresh garlic is beneficial but boiling onions reduces useful chemicals.

Previous studies have found that allium vegetables have nutrients and bioactive compounds that can cut the risk of cancer, particularly cancers of the gastrointestinal tract, the report said. (IANS)

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Consume Low-Fat Diet To Decrease Colon Cancer Risk

High-fat diet may increase risk of developing colon cancer

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High-fat diet
A high-fat diet can lead to the development of colon cancer. Pixabay

Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a new study.

The study, published in the journal Gastroenterology, described a new connection between the way cells consume fat and how genes regulate stem cell behaviour in the intestines of mice.

“This is important because scientists have shown that when there’s too much dietary fat in the intestine, stem cell numbers increase, boosting susceptibility to colon cancer,” said senior author Michael Verzi, associate professor in the Department of Genetics at Rutgers University-New Brunswick.

People naturally lose millions of intestinal cells daily, much like they lose skin cells.

Dietary fat
When there’s too much dietary fat in the intestine, stem cell numbers increase. Pixabay

Intestinal stem cells undergo constant renewal and fuel the continuous turnover of the lining of the intestine, but altered stem cell functions can lead to colon cancer.

Recent studies have shown that intestinal stem cells can increase in animals on a high fat “Western” diet, potentially explaining an elevated cancer risk from such a diet.

The team recently discovered that two genes (HNF4A and HNF4G) work together to promote the proper function of the intestinal lining.

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In the new study, they found that mice lost intestinal stem cells when these genes were inactivated, confirming their importance. Scientists believe that the genes help stem cells burn fat, providing them energy.

Going forward, the researchers hope to further investigate whether the two genes alter stem cell numbers and cancer risk during a high fat diet, said Verzi, who is also a member of the Rutgers Center for Lipid Research. (IANS)