Wednesday June 26, 2019

Researchers Identify Gene Linked to Obesity in Children

Approximately 70 per cent of the human population carries at least one variant of this polymorphism, which is associated with an increased risk of obesity

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Researchers have identified a common gene variant that increases the risk of obesity in children.
In a study published in Obesity journal, the researchers from University of Columbia found that a specific variant (single nucleotide polymorphism) of a gene called “FTO” affects eating behaviour that may be predictive of subsequent weight gain in children, who are at obesity risk.
“Early identification of the physiology and behaviours that constitute early risk factors for subsequent weight gain will help inform best practices for intervention and prevention of obesity in children,” said study author Michael Rosenbaum, a professor at Columbia University.
“This study shows that even before the development of an obese phenotype, children at risk, in this case by virtue of a common genetic variant, exhibit increased food intake,” added Rosenbaum.
For the study, the researchers included 122 children in the 5-10 year age group.
Obesity can now be cured by our body's natural weighing scales.
Obesity can now be cured by our body’s natural weighing scales.
The study discovered that children who are at risk of obesity due to this genetic variant had an increased calorie intake which may contribute to gaining excess weight.
“Even though 65 calories is not a lot per se, if this pattern generalized to multiple meals per week or day, this increased caloric intake can add up over time and may contribute to gaining excess weight,” said Rosenbaum.
According to the researchers, the report could be used to further study children at obesity risk for other reasons.
“The ultimate goal is to prevent the at-risk child or the child who has obesity from becoming an adult with obesity,” added Rosenbaum.
Approximately 70 per cent of the human population carries at least one variant of this polymorphism, which is associated with an increased risk of obesity. (IANS)

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Having a Cup of Coffee Can Help You Fight Obesity, Diabetes

“The results were positive and we now need to ascertain that caffeine as one of the ingredients in the coffee is acting as the stimulus or if there’s another component helping with the activation of brown fat. We are currently looking at caffeine supplements to test whether the effect is similar,” Symonds added

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coffee
A patron holds an iced beverage at a Starbucks coffee store in Pasadena, Calif., July 25, 2013. VOA

Drinking a cup of coffee can be helpful in fighting obesity and diabetes as it stimulates body’s fat-fighting defences, says a new study.

The study, published in Scientific Reports journal, found components which could have a direct effect on “brown fat” functions, an important part of the human body which plays a key role in how quickly we can burn calories as energy.A

Brown adipose tissue (BAT), also known as brown fat, is one of two types of fat found in humans and other mammals. Its main function is to generate body heat by burning calories (opposed to white fat, which is a result of storing excess calories).

People with a lower body mass index (BMI) therefore have a higher amount of brown fat.

“Brown fat works in a different way to other fat in your body and produces heat by burning sugar and fat, often in response to cold. Increasing its activity improves blood sugar control as well as improving blood lipid levels and the extra calories burnt help with weight loss,” said study’s co-director Michael Symonds, Professor at the University of Nottingham.. A

“This is the first study in humans to show that something like a cup of coffee can have a direct effect on our brown fat functions. The potential implications of our results are pretty big, as obesity is a major health concern for society and we also have a growing diabetes epidemic and brown fat could potentially be part of the solution in tackling them,” he noted.

A barista pours steamed milk into a cup of coffee at a cafe in Los Angeles, Sept. 22, 2017. State health officials proposed a regulation change Friday that would declare coffee doesn't present a significant cancer risk, countering a California court ruling.
A barista pours steamed milk into a cup of coffee at a cafe in Los Angeles, Sept. 22, 2017. VOA

For the study, the researcehes started with a series of stem cell studies to see if caffeine would stimulate brown fat. After finding the right dose, they then moved on to humans to see if the results were similar.

They used a thermal imaging technique to trace the body’s brown fat reserves. The non-invasive technique helps the team to locate brown fat and assess its capacity to produce heat.

“From our previous work, we knew that brown fat is mainly located in the neck region, so we were able to image someone straight after they had a drink to see if the brown fat got hotter,” he said.

Also Read: Poor Sleep Quality Associated with Reduced Memory in Senior Citizens

“The results were positive and we now need to ascertain that caffeine as one of the ingredients in the coffee is acting as the stimulus or if there’s another component helping with the activation of brown fat. We are currently looking at caffeine supplements to test whether the effect is similar,” Symonds added.

“Once we have confirmed which component is responsible for this, it could potentially be used as part of a weight management regime or as part of glucose regulation programme to help prevent diabetes,” he concluded. (IANS)