Monday June 17, 2019

Scientists Identified 80 Genes That Trigger Depression

Nearly 80 genes that could be linked to depression have been identified, a finding that adds to the evidence that it is partly a genetic disorder, say scientists. Depression, a common mental disorder, is the leading cause of ill health and disability worldwide.

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Suspension may lead to depression.
Suspension may lead to depression. Pixabay

Nearly 80 genes that could be linked to depression have been identified, a finding that adds to the evidence that it is partly a genetic disorder, say scientists.

Depression, a common mental disorder, is the leading cause of ill health and disability worldwide.

According to the latest estimates from the World Health Organisation (WHO), more than 300 million people are now living with depression, an increase of more than 18 per cent between 2005 and 2015.

“This study identifies genes that potentially increase our risk of depression, adding to the evidence that it is partly a genetic disorder,” said lead author David Howard, research fellow at the University of Edinburgh.

Some of the pinpointed genes are known to be involved in the function of synapses, tiny connectors that allow brain cells to communicate with each other through electrical and chemical signals, the researchers said.

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Old Woman. pixabay

The study could help explain why some people may be at a higher risk of developing the condition as well as help researchers develop drugs to tackle mental health conditions.

“The findings also provide new clues to the causes of depression and we hope it will narrow down the search for therapies that could help people living with the condition,” Howard added.

For the study, published in Nature Communications, the team scanned the genetic code of 300,000 people to identify areas of DNA that could be linked to depression.

The WHO has identified strong links between depression and substance use disorders and diabetes and heart disease.

Studies Show: Elderly With Symptoms of Depression Are More Prone to Memory Problems

Depression is also an important risk factor for suicide, which claims hundreds of thousands of lives each year.

Lack of support for people with mental disorders, coupled with a fear of stigma, prevent many from accessing the treatment they need to live healthy, productive lives. (IANS)

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Depression May Put Women at Risk of Chronic Diseases, Says Study

Women with both conditions — depression and chronic diseases — were more likely to come from low-income households, be overweight and inactive, smoke tobacco and drink alcohol

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depression
Depression has significantly increased the risk of early death in women. Wikimedia

Women who experience symptoms of depression, even without a clinical diagnosis, are at an increased risk of developing multiple chronic diseases, according to a study.

The study, published in the journal American Psychological Association Health Psychology, examined 7,407 middle-aged women (45-50 years) for over 20 years.

During the study period, 43.2 per cent women experienced elevated symptoms of depression and just under half the cohort were diagnosed or took treatment for depression.

Of the total, 2,035 or 63.6 per cent developed multiple chronic diseases.

“These days many people suffer from multiple chronic diseases such as diabetes, heart disease, stroke and cancer. We looked at how women progress in the development of these chronic diseases before and after the onset of depressive symptoms,” said Xiaolin Xu from the University of Queensland in Australia.

Depression
Depression is a common mental disorder. Flickr

“Experiencing depressive symptoms appeared to amplify the risk of chronic illness,” Xu said, adding that women suffering from depression were 1.8 times more likely to have multiple chronic health conditions.

“After women started experiencing these symptoms, they were 2.4 times more likely to suffer from multiple chronic conditions compared to women without depressive symptoms,” he added.

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Women with both conditions — depression and chronic diseases — were more likely to come from low-income households, be overweight and inactive, smoke tobacco and drink alcohol.

“Maintaining a healthy weight, exercising regularly, eating a balanced diet, and reducing harmful behaviours could help prevent and slow the progression of multiple chronic diseases,” Xu said. (IANS)