Saturday February 29, 2020

Genes Tied to Obesity May Lower Risk of Diabetes

"Meanwhile, some lean or normal weight individuals develop diseases like Type-2 diabetes," Yaghootkar noted

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Diabetes
According to the researchers, these novel findings may provide the basis for new therapies for patients who have heart disease complicated by diabetes. Pixabay

Certain genetic factors may impact our body in intriguingly paradoxical ways. A team of scientists has identified 14 new genetic variations that were linked with higher Body Mass Index (BMI) but have the potential to lower risk of diabetes, lower blood pressure and lower heart disease risk.

According to researchers, it is because the location — around middle or round the liver — where surplus fat is stored could be genetically determined.

This location is more important than the amount when it comes to insulin resistance and risk of diabetes and other conditions.

“There are some genetic factors that increase obesity, but paradoxically reduce metabolic risk. It is to do with where on the body the fat is stored,” said Brunel Alex Blakemore, Professor at the Brunel University London.

The findings revealed that as they gain weight, people who carry these genetic factors store it safely under the skin, and so have less fat in their major organs such as the liver, pancreas and kidneys.

Diabetes
Representational image. Pixabay

“Directly under the skin is better than around the organs or especially, within the liver,” Blakemore added.

For the study, published in the journal Diabetes, the team examined more than 500,000 people aged between 37 and 73.

They used Magnetic Resonance Imaging (MRI) scans of these people’s waists to match where they stored extra fat with whether they showed signs of Type-2 diabetes, heart attack and risk of stroke.

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“There are many overweight or obese individuals who do not carry the expected metabolic disease risks associated with higher BMI,” explained Hanieh Yaghootkar from the University of Exeter in Britain.

“Meanwhile, some lean or normal weight individuals develop diseases like Type-2 diabetes,” Yaghootkar noted. (IANS)

Next Story

All you Need to Know About Pet Obesity

Is your pet obese? Here are ways to tackle pet obesity

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Pet obesity
Pet obesity is a direct result of changing pet lifestyles. Pixabay

BY SIDDHI JAIN

An extra treat here, a lazy day-in there, all this can lead to your pet being obese. It is hard to ignore that puppy face your pet makes while he or she watches you eat, but as per experts, pet obesity is a direct result of changing pet lifestyles.

“Pets and pet owners have evolved in the last couple of decades. More food options, reduced open spaces for pets and busy work culture for pet parents have all contributed to a very different lifestyle for pets in the country. All these factors contribute significantly to pet obesity which is very much a cause of concern,” Gaurav Kwatra, Director, PURINA Petcare India, told IANSlife.

The pet nutrition brand, which developed a nine-stage Body Conditioning system to assess pets, has also done a 14-year lifespan study with dogs. Results show that dogs that maintain a lean muscle mass live a life upto 15 per cent longer with better quality of life.

It’s almost a natural instinct to feed our furry companions whatever you are eating. What goes ignored is the fact that, pets also prone to obesity and overindulgence may be harmful to the pet’s health in the long run.

Pet obesity
Extra treat or a lazy day could lead to pet obesity. Pixabay

“Apart from the overindulgence, there are plenty of factors that can cause obesity in pets. Sometimes, obesity in pets could be caused by thyroid problems. However, in most cases, obesity is linked to lifestyle and the nutrition intake,” Kwatra adds.

What could be the ill-effects of obesity in pets?

Obesity in pets can not only be highly detrimental to their health but also cause discomfort for them in performing day to day activities. Obese pets are usually far less active and are susceptible to conditions like arthritis, diabetes mellitus, cardio-pulmonary problems, constipation, cancer and even premature death.

Can this be cured or reversed by administering a certain kind of food only?

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While the emergence of specialized diets would play a vital role in countering the epidemic, together with the veterinarians we need to raise awareness on pet obesity and educate pet owners/parents on how they can help their pets lead a healthier and happier life with proper nutrition. Proper exercise is also crucial in maintaining a pet’s health and it is imperative that pet parents take them out for regular walks. (IANS)