Wednesday March 27, 2019

Green Tea, Carrots May Show Promise Against Alzheimer’s, Says Study

The researchers noted that many mouse discoveries never translate into human treatments

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In Alzheimer's disease, patients start losing memory. Pixabay

A diet containing compounds found in green tea and carrots reversed Alzheimer’s-like symptoms in mice genetically programmed to develop the disease, an advance that could one day pave the way for treatment of dementia in humans, say researchers.

The study, led by the University of Southern California in the US, supports the idea that combination therapy, rather than a single magic bullet, may offer the best approach to treating people living with Alzheimer’s.

Combination treatment is already the standard of care for diseases such as cancer, HIV infection and rheumatoid arthritis.

The findings, published in the journal Biological Chemistry, showed that a combination of EGCG, or epigallocatechin-3-gallate – found in green tea; and FA, or ferulic acid – found in carrots, tomatoes, rice, wheat and oats, completely restored spatial working memory.

After three months of treatment, the Alzheimer’s mice performed just as well as the healthy comparison mice.

A lady suffering from Alzheimer’s. Flickr

“You don’t have to wait 10 to 12 years for a designer drug to make it to the market. You can make these dietary changes today. I find that very encouraging,” said Terrence Town, Professor at the varsity.

For the study, the researchers assigned 32 mice with Alzheimer’s-like symptoms to one of four groups with an equal number of males and females for three months.

The dosage was 30 milligrams per kilogram of body weight – a dosage well-tolerated by humans and easily consumed as part of a healthy diet.

Also Read- High Levels of Testosterone May Raise Heart Failure Risk in Men

The researchers noted that many mouse discoveries never translate into human treatments.

However, the findings lend credence to the idea that certain readily available, plant-based supplements might offer protection against dementia in humans, they said. (IANS)

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Drinking Green Tea Can Help Reduce Obesity, Inflammation

Drinking green tea has also been linked to a lower risk of cancer, heart and liver disease

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Green tea is the second most consumed beverage.
Green tea is believed to have therapeutic intervention to cure a variety of diseases. Pixabay

Want to cut that extra flab? Drinking green tea can help reduce obesity as well as inflammation in the gut, finds a study.

The findings, published in the Journal of Nutritional Biochemistry, showed that mice fed a high-fat diet supplemented with green tea gained about 20 per cent less weight and had lower insulin resistance than mice fed an otherwise identical diet without tea.

Mice fed a diet of two per cent green tea extract had an improved gut health including more beneficial microbes in the intestines and less permeability in the intestinal wall — a condition called “leaky gut” — than those that ate a diet without it.

Leaky gut is a problem in humans that contributes to widespread low-grade inflammation.

“This study provides evidence that green tea encourages the growth of good gut bacteria, and that leads to a series of benefits that significantly lower the risk of obesity,” said lead author Richard Bruno, Professor at the Ohio State University.

Green tea. Pixabay

For eight weeks, the team fed half of the male mice a high-fat diet that causes obesity and half were fed a regular diet. In each of those groups, half ate green tea extract mixed with their food.

Female mice were not included as they are resistant to diet-induced obesity and insulin resistance.

Green tea also protected against the movement of endotoxin — the toxic bacterial component — out of their guts and into the bloodstream.

Also Read- Jharkhand Government Bans Sale and Usage of E-cigarettes

“Consuming a little throughout the course of a day with food might be better,” Bruno said.

Drinking green tea has also been linked to a lower risk of cancer, heart and liver disease. (IANS)