Sunday December 8, 2019

Gum Disease Can Be a Potential Risk Factor for Increased Blood Pressure

Hypertension could be the driver of heart attack and stroke in patients with periodontitis

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Gum Disease
High Blood Pressure affects 30-45 per cent of adults and is the leading global cause of premature death, while Gum Disease affects more than 50 per cent of the world's population. Pixabay

People with Gum Disease (periodontitis) have a greater likelihood of suffering from high Blood Pressure or vice versa, warn researchers.

The study investigated gum disease as a potential risk factor for hypertension, but the reverse could also be true.

“Further research is needed to examine whether patients with high blood pressure have a raised likelihood of gum disease. It seems prudent to provide oral health advice to those with hypertension,” said Professor Francesco D’Aiuto from UCL Eastman Dental Institute in the UK.

High blood pressure affects 30-45 per cent of adults and is the leading global cause of premature death, while periodontitis affects more than 50 per cent of the world’s population.

“We observed a linear association — the more severe periodontitis is, the higher the probability of hypertension. The findings suggest that patients with gum disease should be informed of their risk and given advice on lifestyle changes to prevent high blood pressure such as exercise and a healthy diet,” said D’Aiuto in the paper published in Cardiovascular Research, a journal of the European Society of Cardiology.

Hypertension could be the driver of heart attack and stroke in patients with periodontitis.

“Previous research suggests a connection between periodontitis and hypertension and that dental treatment might improve blood pressure, but to date, the findings are inconclusive,” the researchers noted.

This study compiled the best available evidence to examine the odds of high blood pressure in patients with moderate and severe gum disease.

Blood Pressure
People with gum disease (periodontitis) have a greater likelihood of suffering from high Blood Pressure or vice versa, warn researchers. Pixabay

A total of 81 studies from 26 countries were included in the meta-analysis.

Moderate-to-severe periodontitis was associated with a 22 per cent raised risk for hypertension, while severe periodontitis was linked with 49 per cent higher odds of hypertension.

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Average arterial blood pressure was higher in patients with periodontitis compared to those without. An average 5 mmHg blood pressure rise would be linked to a 25 per cent increased risk of death from heart attack or stroke, the researchers noted. (IANS)

Next Story

Blood Test Can Identify Risk of Night-Time High Blood Pressure in People

Most people experience lower blood pressure at night

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Blood Test
A simple Blood Test administered at the beginning of a sleep study could indicate each patient's cardiovascular risk, said the study. Pixabay

Researchers have found that a simple Blood Test can help identify people with obstructive sleep apnea (OSA) who are at higher risk of cardiovascular problems because of a phenomenon called “reverse dipping” that causes blood pressure to rise rather than lower during sleep.

Most people experience lower blood pressure at night. The new study, published in the European Respiratory Journal suggests a potential cause for reverse dipping that may help patients with sleep apnea get the help they need before cardiovascular disease develops.

“We can now identify those with OSA at the highest risk of cardiovascular problems in order to prevent them from developing additional complications,” said David Gozal from the University of Missouri School of Medicine in the US.

“We can treat those patients more aggressively to ensure they adhere to therapy and use their continuous positive airway pressure device (CPAP) properly,” Gozal said.

The researchers studied 46 patients diagnosed with OSA. They ranged in age from 18 to 70. Fifteen participants were identified to have a rise in blood pressure during sleep, while the remaining 31 participants had blood pressure readings that either remained the same or declined at night.

The researchers collected a blood sample from each participant to study the messages cells produce and send to each other through microscopic packages called exosomes.

Blood Test
Researchers have found that a simple Blood Test can help identify people with obstructive sleep apnea (OSA) who are at higher risk of cardiovascular problems because of a phenomenon called “reverse dipping” that causes blood pressure to rise rather than lower during sleep. Pixabay

“We found that the cell messages coming from participants with night-time elevated blood pressure were different than those transmitted in subjects with normal blood pressure,” Gozal said.

“The altered messages caused the cells that line the blood vessels to become dysfunctional. Those disturbed vessels allowed inflammatory cells to enter the vessels’ walls, causing hardening of those vessels and leading to cardiovascular disease.”

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Gozal said the cell message discovery will help clinicians personalise treatment for each patient diagnosed with OSA.

A simple blood test administered at the beginning of a sleep study could indicate each patient’s cardiovascular risk, said the study. (IANS)