Tuesday December 11, 2018

Gut Bacteria Linked to Atherosclerosis, Which is Further Linked to Heart Attack

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

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The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.
Gut Bacteria, Pixabay
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The gut microbiome plays an important role in an individual’s risk for atherosclerosis, one of the major causes of heart attack and stroke, says a study.

It is a disease in which plaque builds up in the arteries.

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.
Atherosclerosis causes Heart Attack, Pixabay

They studied 316 people from different groups of patients, including those with unexplained atherosclerosis, who do not have any traditional risk factors but still have high levels of plaque burden.

“What we found was that patients with unexplained atherosclerosis had significantly higher blood levels of these toxic metabolites that are produced by the intestinal bacteria,” said David Spence, Professor at Western University, London, Canada.

The researchers measured the build-up of plaque in the arteries using carotid ultrasound.

Also Read: Italy School Restrict Kids Due to Incomplete Immunization

The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.

“The finding, and studies we have performed since, present us with an opportunity to use probiotics to counter these compounds in the gut and reduce the risk of cardiovascular disease,” said Gregor Reid, Professor at Schulich School of Medicine and Dentistry at Western University.

Repopulation of the intestinal microbiome is another novel approach to treatment of atherosclerosis that arises from this study, Spence added. (IANS)

 

 

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Smoking, High BP Increases Risk of Heart Attack Recurrence

Previous studies have defined young heart attack patients as less than 45-years-old while some used a less than 40-year-old cut-off

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Smoking, high BP raises risk of heart attack relapse: Study. Pixabay

Young men who are chain smokers or suffer from hypertension could be at an increased risk of heart attack recurrence, researchers have warned.

The study found that risk factors such as smoking, high blood pressure, family history of heart disease and chronic kidney disease were more prevalent among the patients who experienced a relapse.

“When treating younger patients with a history of heart attack, clinicians should emphasise better control of high blood pressure, high cholesterol and diabetes,” said Joanne Karen Recacho-Turingan, a cardiology student from The Medical City in Manila, Philippines.

“Other modifiable risk factors to highlight in patient history and address with these patients include smoking habits and obesity,” Recacho-Turingan added.

The findings were presented at the Asia Conference 2018 in Shanghai.

blood pressure
BP-monitoring machine. Pixabay

For the study, researchers analysed 133 young patients and found that males (90.1 per cent) with an average age of 40.9 years, experienced a second heart attack compared to females (9.9 per cent) with an average age of 39.6 years.

In addition, in these male patients, chest pain was the most common presenting symptom (81.8 per cent) while 90.9 per cent had unstable vital signs.

Heart attack in young patients can cause disability and even death at the prime of life. There are often serious consequences for these patients, their families and the health system, which can lead to an increased economic burden, according to the study.

Also Read- New Drug Offers Treatment For Diabetes-Related Blindness

“We must make sure to work with these patients on their modifiable risk factors to reduce their risk not just for a second heart attack, but hopefully, even preventing the first,” Recacho-Turingan noted.

Previous studies have defined young heart attack patients as less than 45-years-old while some used a less than 40-year-old cut-off. (IANS)