Thursday August 22, 2019

Gut Bacteria Linked to Atherosclerosis, Which is Further Linked to Heart Attack

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

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The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.
Gut Bacteria, (Representational image). Pixabay

The gut microbiome plays an important role in an individual’s risk for atherosclerosis, one of the major causes of heart attack and stroke, says a study.

It is a disease in which plaque builds up in the arteries.

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.
Atherosclerosis causes Heart Attack, Pixabay

They studied 316 people from different groups of patients, including those with unexplained atherosclerosis, who do not have any traditional risk factors but still have high levels of plaque burden.

“What we found was that patients with unexplained atherosclerosis had significantly higher blood levels of these toxic metabolites that are produced by the intestinal bacteria,” said David Spence, Professor at Western University, London, Canada.

The researchers measured the build-up of plaque in the arteries using carotid ultrasound.

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The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.

“The finding, and studies we have performed since, present us with an opportunity to use probiotics to counter these compounds in the gut and reduce the risk of cardiovascular disease,” said Gregor Reid, Professor at Schulich School of Medicine and Dentistry at Western University.

Repopulation of the intestinal microbiome is another novel approach to treatment of atherosclerosis that arises from this study, Spence added. (IANS)

 

 

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Heart Attack Cases Higher in Areas with More Fast Food Outlets: Researchers

“The ubiquitous presence of fast food is an important consideration for the ongoing development of rural and metropolitan areas,” he said

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While it is known that eating fast food is not good for health, researchers, including one of an Indian-origin, have found that areas with a higher number of fast food outlets record more heart attack cases.

Published in the European Heart Journal, the findings also showed that for every additional fast food outlet, there were four additional heart attacks per 100,000 people each year.

The findings were consistent across rural and metropolitan areas after adjusting for age, obesity, high blood lipids, high blood pressure, smoking status, and diabetes. The results emphasise the importance of the food environment as a potential contributor towards health, said Indian-origin researcher Tarunpreet Saluja from the University of Newcastle in Australia.

This retrospective cohort study included 3,070 patients admitted to hospital with a heart attack between 2011 and 2013.

Fast Food. Image Source: Wikimedia Commons

The researchers recorded the total number of outlets within each local government area and compared different areas to analyse the association between density of fast food restaurants and incidence of heart attack.

“The ubiquitous presence of fast food is an important consideration for the ongoing development of rural and metropolitan areas,” he said.

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“This study highlights the impact of the food environment on health. In addition to regulating the location and density of fast food outlets, local areas should ensure good access to supermarkets with healthy food,” said Jeroen Bax, Professor at the Leiden University in Netherlands. (IANS)