Saturday August 18, 2018

Gut Bacteria Linked to Atherosclerosis, Which is Further Linked to Heart Attack

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

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The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.
Gut Bacteria, Pixabay
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The gut microbiome plays an important role in an individual’s risk for atherosclerosis, one of the major causes of heart attack and stroke, says a study.

It is a disease in which plaque builds up in the arteries.

The researchers believe that the new finding could open the door for new treatment options for those patients with unexplained plaque build-up in the arteries.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.

In order to understand the role that bacteria in the gut may play in atherosclerosis, the researchers examined blood levels of metabolic products of the intestinal microbiome.
Atherosclerosis causes Heart Attack, Pixabay

They studied 316 people from different groups of patients, including those with unexplained atherosclerosis, who do not have any traditional risk factors but still have high levels of plaque burden.

“What we found was that patients with unexplained atherosclerosis had significantly higher blood levels of these toxic metabolites that are produced by the intestinal bacteria,” said David Spence, Professor at Western University, London, Canada.

The researchers measured the build-up of plaque in the arteries using carotid ultrasound.

Also Read: Italy School Restrict Kids Due to Incomplete Immunization

The study, published in the journal Atherosclerosis, noted that these differences could not be explained by diet or kidney function, pointing to a difference in the make-up of their intestinal bacteria.

“The finding, and studies we have performed since, present us with an opportunity to use probiotics to counter these compounds in the gut and reduce the risk of cardiovascular disease,” said Gregor Reid, Professor at Schulich School of Medicine and Dentistry at Western University.

Repopulation of the intestinal microbiome is another novel approach to treatment of atherosclerosis that arises from this study, Spence added. (IANS)

 

 

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Heart Attack Risk on The Rise for Pregnant Women and Death Rate Remains High

Patients should work out a plan with their physicians to monitor and control risk factors during pregnancy so that they can minimize their risk

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According to the researchers, an increased number of women are obese or have diabetes, which are the key risk factors for a heart attack.
According to the researchers, an increased number of women are obese or have diabetes, which are the key risk factors for a heart attack. Pixabay

The risk of having a heart attack while pregnant, giving birth, or during two months after delivery, continues to increase, a US-based study has found.

The findings, published in the journal Mayo Clinic Proceedings, suggest that the trend among many women to have children later in life is one possible reason for the increase, as the3 heart attack risk rises with age overall, and especially during pregnancy.

“Our analysis, the largest review in a decade, serves as an important reminder of how stressful pregnancy can be on the female body and heart, causing a lot of physiological changes, and potentially unmasking risk factors that can lead to heart attack,” said co-author Sripal Bangalore from the New York University Langone Health.

According to the researchers, an increased number of women are obese or have diabetes, which are the key risk factors for a heart attack.

highlight the importance to women considering pregnancy to know their risk factors for heart disease beforehand,
It highlights the importance to women considering pregnancy to know their risk factors for heart disease beforehand. Pixabay

For the study, the researchers examined 49,829,753 births recorded in hospitals — where the majority of deliveries in the US take place — and found that 1,061 heart attacks happened during labour and delivery.

They also found that another 922 women were hospitalized for myocardial infarction before birth, and 2,390 heart attacks occurred during the recovery period after birth.

The researcher said that although the absolute number of heart attacks and deaths from them remain low, the persistence of the relatively high death rate (unchanged at 4.5 per cent of cases) comes despite advances in treating heart attacks with drug-coated stents and improved use of blood-thinning medications to prevent heart-vessel blockages.

Also Read: Being Positive During Pregnancy May Lead to Kids Being in Shape: Study

“Our findings highlight the importance to women considering pregnancy to know their risk factors for heart disease beforehand,” said lead author Nathaniel Smilowitz from the varsity.

“These patients should work out a plan with their physicians to monitor and control risk factors during pregnancy so that they can minimize their risk,” Smilowitz noted. (IANS)