Tuesday September 25, 2018

How Gut Bacteria May Increase Obesity Risk

The study, published in the Journal of Clinical Endocrinology and Metabolism, mentioned that the gut microbiota affects our metabolism and lead to cardiovascular diseases and Type 2 diabetes

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The presence of gut flora in the intestines may cause health benefits for some people, whereas it increases obesity risk in the others, researchers have claimed.

While sourcing a new link between gut bacteria and obesity risk, the animal-based study found that certain amino acids in our blood can be connected to both obesity risk and the composition of the gut microbiome.

ALSO READ: Children at Risk: Obesity is not limited to the Urban-Rich of India

The study, published in the Journal of Clinical Endocrinology and Metabolism, mentioned that the gut microbiota affects our metabolism and lead to cardiovascular diseases and Type 2 diabetes.

obesity risk
Previous studies have shown that people with these diseases have a varying occurrence of different metabolites, that is small molecules or metabolic residues, in the bloodstream. Pixabay

 

The researchers analyzed blood plasma and stool samples from 674 participants in the Malmö Offspring Study (MOS).

ALSO READ: WHO Releases New Guidelines to Fight Global Childhood Obesity

They found 19 different metabolites that could be linked to the person’s body mass index (BMI); glutamate and so-called BCAA (branched-chain and aromatic amino acids) had the strongest connection to obesity.

“The differences in BMI were largely explained by the differences in the levels of glutamate and BCAA. This indicates that the metabolites and gut bacteria interact, rather than being independent of each other,” said Marju Orho-Melander, Professor at Lund University in Sweden.

Previous studies have also shown that the manipulation of the gut bacteria may cut down diabetes, bowel diseases, and obesity risk. (IANS)

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Exposure to Certain Disinfectants Can Cause Obesity in Kids: Research

The use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits.

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Disinfectants
How common household cleaners could make kids overweight. Flickr

Early life exposure to certain disinfectants used at home could be making children overweight by altering the composition of their gut bacteria, suggests new research.

Babies living in households that used eco-friendly cleaners had different microbiota and were less likely to be overweight as toddlers, showed the findings published in CMAJ (Canadian Medical Association Journal).

For the study, the researchers analysed the gut flora of 757 infants from the general population at age 3-4 months and weight at ages 1 and 3 years, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Disinfectants
Mother’s Lifestyle Choices Linked to Obesity Risk in Adolescents. Pixabay

The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. They used World Health Organization growth charts for body mass index (BMI) scores.

Associations with altered gut flora in babies 3-4 months old were strongest for frequent use of household disinfectants such as multi-surface cleaners, which showed lower levels of Haemophilus and Clostridium bacteria but higher levels of Lachnospiraceae.

The researchers also observed an increase in Lachnospiraceae bacteria with more frequent cleaning with disinfectants.

They, however, did not find the same association with detergents or eco-friendly cleaners.

“We found that infants living in households with disinfectants being used at least weekly were twice as likely to have higher levels of the gut microbes Lachnospiraceae at age 3-4 months,” said Anita Kozyrskyj, Professor at the University of Alberta in Canada.

Disinfectants
The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. Flcikr

“When they were 3 years old, their body mass index was higher than children not exposed to heavy home use of disinfectants as an infant,” Kozyrskyj said.

“Those infants growing up in households with heavy use of eco cleaners had much lower levels of the gut microbes Enterobacteriaceae,” she said.

Also Read: Asthma Ups The Chance of Obesity: Study

Kozyrskyj suggests that the use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits, contributing in turn to the healthier gut microbiomes and weight of their infants. (IANS)