Friday, April 23, 2021
Home Life Style Health & Fitness Gut Microbiome Play A Key Role In Treating Type 2 Diabetes

Gut Microbiome Play A Key Role In Treating Type 2 Diabetes

Dysbiosis is commonly associated with detrimental effects on a person's health

Researchers at Oregon State University in the US have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease.

The human gut microbiome features more than 10 trillion microbial cells from about 1,000 different bacterial species.

Dysbiosis, or imbalance, in the microbiome, is commonly associated with detrimental effects on a person’s health.

Follow NewsGram on Twitter to stay updated about the World news.

According to study co-leader Andrey Morgun, the so-called ‘western diet’ – high in saturated fats and refined sugars – is one of the primary factors.

“But gut bacteria have an important role to play in modulating the effects of diet.”

A key risk factor for type 2 diabetes is being overweight, often a result of a western diet in combination with low physical activity.

“Some studies suggest dysbiosis is caused by complex changes resulting from interactions of hundreds of different microbes,” said Natalia Shulzhenko, an associate professor of biomedical sciences.

Follow NewsGram on Instagram to keep yourself updated.

“However, our study and other studies suggest that individual members of the microbial community, altered by diet, might have a significant impact on the host.”

Shulzhenko and Morgun used a new, data-driven, systems-biology approach called transkingdom network analysis to study host-microbe interactions under a western diet.

Gut Microbiome
Microbe could be a prevalent pathobiont in overweight people. Pixabay

That allowed them to investigate whether individual members of the microbiota played a part in metabolic changes the diet induces in a host.

Want to read more in Hindi? Checkout: बारिश, आद्र्रता से आलू पर पिछेता झुलसा का खतरा, जानिए बचाव के उपाय

“The analysis pointed to specific microbes that potentially would affect the way a person metabolizes glucose and lipids,” Morgun said.

The scientists identified four operational taxonomic units, or OTUs, that seemed to affect glucose metabolism; OTUs are a means of categorizing bacteria based on gene sequence similarity.

The identified OTUs corresponded to four bacterial species: Lactobacillus johnsonii, Lactobacillus gasseri, Romboutsia ilealis, and Ruminococcus gnavus.

Checking the mouse results against data from an earlier human study, the scientists found correlations between human body mass index and abundance of the four bacteria – more of the improvers meant a better body mass index, more of the worsened was connected to a less healthy BMI.

“We found R. ilealis to be present in more than 80 percent of obese patients, suggesting the microbe could be a prevalent pathobiont in overweight people,” Shulzhenko said.

ALSO READ: 10 Naturopathy And Yoga Tips To Help People With Diabetes

“Our study reveals potential probiotic strains for treatment of type 2 diabetes and obesity as well as insights into the mechanisms of their action,” Morgun said in a paper published in Nature Communications.

“That means an opportunity to develop targeted therapies rather than attempting to restore ‘healthy’ microbiota in general.” (IANS)

STAY CONNECTED

19,507FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

Amitabh Bachchan: An Inspiration

By- Khushi Bisht Amitabh Bachchan, also known as Big B, is without a doubt Bollywood's biggest star. The 78-year-old Bollywood megastar has been a hugely...

Does Congress Party Have A Future In Face Of Modi Onslaught?

It was India’s “Grand Old Party.” The Congress Party ruled the country for 55 out of 71 years since independence. But following the party’s...

WHO: An Initiative To Halt The Transmission Of Malaria By 2025

The World Health Organization (WHO) is launching a new initiative that aims to halt the transmission of malaria in 25 more countries by 2025....

Largest Flare Ever Recorded From The Sun’s Nearest Neighbor

Scientists have spotted the largest flare ever recorded from the sun's nearest neighbor, the star Proxima Centauri. Proxima Centauri is a small but mighty...

Understanding Obsessive Compulsive Disorder (OCD)

BY- JAYA CHOUDHARY Many of us have our own unique habits and practices that we follow on a regular basis, such as bringing a lucky...

“Bangladesh: The Price of Freedom”: Relive The Horrors Of Bangladesh Liberation

Ace photographer Raghu Rai was only five years into the profession when the Bangladesh liberation struggle erupted in March 1971. He was dispatched post-haste...

What Makes SARS-CoV-2 More Deadly?

Researchers have found that the cell types, which the SARS-CoV-2 -- the virus behind Covid-19 -- infects, make it more deadly. The study, led...

UI , Auto Zoom And More Will Be Introduced By Google In Meet App

Google has announced to introduce new innovations in its Meet app like a refreshed user interface (UI), autozoom, enhanced reliability features powered by the...

Recent Comments