Tuesday January 21, 2020

Heavier, Taller Children More Likely to Develop Kidney Cancer, Warn Researchers

The study was presented at the European Congress on Obesity being held in Glasgow, Scotland from April 28 to May 1

Cancer Ribbon. Pixabay

Heavier and taller children are more likely to develop kidney cancer as adults than their average-sized peers, warn researchers.

“We know that overweight in adulthood is associated with an increased risk of renal cell carcinoma (RCC). We also know that cancers take many years to develop. We therefore had a theory that already being overweight in childhood would increase the risk of RCC later in life,” said lead author Britt Wang Jensen from Bispebjerg and Frederiksberg Hospital in Denmark.

RCC is the most common form of kidney cancer found in adults.

For the study, the researchers included 301,422 individuals from the Copenhagen School Health Records Register born from 1930 to1985.

The weights and heights were measured at the ages seven to 13 years, and body mass index (BMI) was used to categorise the children as normal-weight or overweight, suggested by the International Obesity Task Force.

The study was published in journal The Lancet Oncology. Wikimedia Commons
The study was published in journal The Lancet Oncology. Wikimedia Commons

During a median of 32 years of observation, 1,010 individuals (680 men) were diagnosed with RCC.

Among men and women, significant and positive associations were observed between childhood BMI and height, respectively, and RCC risk.

Children who grew from average to above average height had an eight per cent increased risk of RCC, the study said.

Also Read- Work Stress, Impaired Sleep Associated with Higher Risk of Cardiovascular Death in People With Hypertension

“Our findings that heavier and taller children have increased risks of RCC open the door to new ways to explore the causes of kidney cancer,” Jensen said.

The study was presented at the European Congress on Obesity being held in Glasgow, Scotland from April 28 to May 1. (IANS)

Next Story

Effect of Air Pollution: Escalates Mortality Risk, Besides Causing Deadly Diseases like Lung and Kidney Cancer

Air pollution can increase the risk of death from kidney, bladder and colorectal cancer besides causing lung cancer

Effect of Air pollution
Air pollution may also lead to deadly diseases like lung and kidney cancer. Pixabay.

London, Nov 1: Air pollution can increase the risk of death from kidney, bladder and colorectal cancer besides causing lung cancer, a study has showed.

According to researchers, air pollution represents a complex mixture of a broad range of carcinogenic and mutagenic substances that may play a role in chronic systemic inflammation, oxidative stress and DNA damage in tissues that could ultimately prove fatal.

“This research suggests that the effect of air pollution was not associated with death from most non-lung cancers, but the associations with kidney, bladder and colorectal cancer deserve further investigation,” said lead author Michelle Turner, researcher at the Barcelona Institute of Global Health (ISGlobal) in Spain.

effect of Air Pollution
The effect of Air Pollution is deadly, causing non lung cancers as well. Pixabay.

For the study, published in the journal Environmental Health Perspectives, the team included more than 600,000 adults in the US and examined associations of mortality from cancer at 29 sites with long-term residential exposure to three ambient pollutants: PM2.5, nitrogen dioxide (NO2) and ozone (O3).

ALSO READ: Air Pollution Expected to cause 60000 deaths by 2030

Over 43,000 non-lung cancer deaths were registered among the participants. PM2.5 was associated with mortality from kidney and bladder cancer, with a 14 and 13 per cent increase respectively, for each 4.4 µg/m3 (microgram) increase in exposure.

In turn, exposure to NO2 was associated with colorectal cancer death, with a 6 per cent increase per each 6.5 ppb (parts per billion) increment.

No significant associations were observed with cancer at other sites. (IANS)