Tuesday February 25, 2020

Here’s How Heavy Smoking Can Make You Look Older

An analysis searched across 18,000 traits and apart from the new finding of more rapid facial aging, also identified several previously reported effects of smoking

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Smoking
The known effects of Smoking includes worse lung function, and higher risk of chronic obstructive pulmonary disease (COPD) and skin cancer. Pixabay

Smoker’s Face– a condition where smokers look older than they are, is just one of many negative effects caused by heavy Smoking, researchers have warned.

“We searched across thousands of traits to identify those that may be affected by how heavily someone smokes. As well as identifying several known adverse effects such as on lung health, we also identified an adverse effect of heavier smoking on facial aging,” said study author Louise Millard from the University of Bristol in UK.

According to the study, published in the journal PLOS Genetics, some people carry one or two copies of a genetic variant that is associated with heavier tobacco use.

To simultaneously identify these two types of effects, the researchers used a novel combination of two data analysis approaches and applied them using data from people in the UK Biobank.

They separated people into two groups. The first contained people who had never smoked, and the second included current and former smokers.

Smoking
Smoker’s Face– a condition where smokers look older than they are, is just one of many negative effects caused by heavy Smoking, researchers have warned. Pixabay

The analysis searched across 18,000 traits and apart from the new finding of more rapid facial aging, also identified several previously reported effects of smoking, confirming the method’s effectiveness.

The known effects of smoking that the analysis identified included worse lung function, and higher risk of chronic obstructive pulmonary disease (COPD) and skin cancer.

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Besides emphasising smoking’s many dangers, the study also serves as proof of principle that these data analysis tools can be used to identify effects of other exposures of interest, such as alcohol intake. (IANS)

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Here’s Why Diabetes May be an Independent Risk Factor For Heart Failure

Diabetes is also a major risk factor for atherosclerosis and this eventually leads to blockage of coronary arteries

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Disease
According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart. Pixabay

Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population.

According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart.

“Diabetes is also a major risk factor for atherosclerosis and this eventually leads to blockage of coronary arteries. This leads to heart attack or myocardial infarction,” Satish Koul, HOD and Director Internal Medicine, Narayana Superspeciality Hospital, Gurugram, told IANS. “Due to myocardial infarction, the heart muscle becomes weak and eventually heart fails as a pump leading to congestive heart failure,” Koul added.

According to the current study, published in the journal Mayo Clinic Proceedings, researchers evaluated the long-term impact of diabetes on the development of heart failure, both with preserved ejection fraction – a measurement of the percentage of blood leaving the heart with each contraction – and reduced ejection fraction.

They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function. From an initial group of 2,042 residents of Olmsted County in US, 116 study participants with diabetes were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without diabetes.

Over the 10-year follow-up period, 21 per cent of participants with diabetes developed heart failure, independent of other causes. In comparison, only 12 per cent of patients without diabetes developed heart failure. Cardiac death, heart attack and stroke were not statistically different in the study between the two groups.

The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Furthermore, the outcome data support the concept of a diabetic cardiomyopathy.

Heart Disease
Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Pixabay

This research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction, diabetic patients are still at increased risk of developing heart failure as compared to their nondiabetic counterparts.

“The key takeaway is that diabetes mellitus alone is an independent risk factor for the development of heart failure,” said study senior author Horng Chen from Mayo Clinic in the US.

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“Our hope is that this study provides a strong foundation for further investigations into diabetes and heart failure. There is still much to learn and study in terms of this association and how to best diagnose and treat this condition,” Chen added. (IANS)