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Study Reveals Medicine Taken To Treat High Blood Pressure Can Lead An Increased Risk of Sudden Cardiac Arrest

The results, presented at the annual congress of European Heart Rhythm Association 2019 in Lisbon, showed that high-dose (60 mg/day) nifedipine was significantly associated with an increased risk of out-of-hospital cardiac arrest with any dose of amlodipine. 

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"Nifedipine and amlodipine are often used by many cardiologists and other physicians, and the choice often depends on the prescriber's preference and personal experience," said Hanno Tan, cardiologist at the Academic Medical Center. VOA

A drug commonly used to treat high blood pressure and chest pain could be associated with an increased risk of sudden cardiac arrest, according to a study.

Doctors from the Academic Medical Center in Amsterdam, the Netherlands, examined over 60,000 people to determine whether nifedipine and amlodipine or dihydropyridines — widely used for high blood pressure and angina — were linked with out-of-hospital cardiac arrest.

The results, presented at the annual congress of European Heart Rhythm Association 2019 in Lisbon, showed that high-dose (60 mg/day) nifedipine was significantly associated with an increased risk of out-of-hospital cardiac arrest with any dose of amlodipine.

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In sudden cardiac arrest, the heart stops pumping after a cardiac arrhythmia (ventricular fibrillation/tachycardia). This can be lethal if untreated. Pixabay

There was no risk associated with amlodipine.

“Nifedipine and amlodipine are often used by many cardiologists and other physicians, and the choice often depends on the prescriber’s preference and personal experience,” said Hanno Tan, cardiologist at the Academic Medical Center.

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A drug commonly used to treat high blood pressure and chest pain could be associated with an increased risk of sudden cardiac arrest, according to a study. Pixabay

The findings are surprising given that both the drugs have been in use for many years.

However, the researchers urged caution when interpreting the results.

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“The findings need to be replicated in other studies before action could be taken by doctors or patients,” Tan said.

In sudden cardiac arrest, the heart stops pumping after a cardiac arrhythmia (ventricular fibrillation/tachycardia). This can be lethal if untreated. (IANS)

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Know About the Health Benefits of Walnuts

Eat walnuts daily for better gut, heart health

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Walnuts could lead to better heart health. Pixabay

Walnuts may not just be a tasty snack, they may also promote good-for-your-gut bacteria, say researchers, adding that these ‘good’ bacteria could lead to better heart health.

The study, published in the Journal of Nutrition, suggests walnut as a part of healthy diet may be a heart- and gut-healthy nut.

Additionally, those changes in gut bacteria were associated with improvements in some risk factors for heart disease.

“Substantial evidence shows that small improvements in diet greatly benefit health. Eating two to three ounces of walnuts a day as part of a healthy diet could be a good way to improve gut health and reduce the risk of heart disease,” said study researcher Kristina Petersen from Penn State University in the US.

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Walnuts as a part of healthy diet may be a heart- and gut-healthy nut. Pixabay

According to the researchers, another research has found that changes to the bacteria in the gastrointestinal tract — also known as the gut microbiome — may help explain the cardiovascular benefits of walnuts.

For the study, the researchers recruited 42 participants with overweight or obesity who were between the ages of 30 and 65.

Before the study began, participants were placed on an average American diet for two weeks.

After this “run-in” diet, the participants were randomly assigned to one of three study diets, all of which included less saturated fat than the run-in diet.

 

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Researchers found that after consuming walnuts, there were significant associations between changes in gut bacteria and risk factors for heart disease. Pixabay

The diets included one that incorporated whole walnuts, one that included the same amount of alpha-linolenic acid (ALA) and polyunsaturated fatty acids without walnuts, and one that partially substituted oleic acid (another fatty acid) for the same amount of ALA found in walnuts, without any walnuts.

In all three diets, walnut or vegetable oils replaced saturated fat, and all participants followed each diet for six weeks with a break between diet periods.

 

Also Read- Consumption of Soybean Oil May Affect Neurological Conditions: Study

The researchers also found that after the walnut diet, there were significant associations between changes in gut bacteria and risk factors for heart disease.

According to the study, Eubacterium eligens was inversely associated with changes in several different measures of blood pressure, suggesting that greater numbers of Eubacterium eligens was associated with greater reductions in those risk factors. (IANS)