Wednesday November 13, 2019

Higher BMI Linked with Asthma Risk, says Study

The participants' weight and height were measured multiple times during the first three years of life

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BMI, Asthma Risk
High BMI in early life is linked to asthma risk later: Study. Pixabay

The growth of children in the first three years of their life affects the development of their lungs and the risk of asthma at 10 years of age, says a study.

According to recent studies, excessive weight gain in the first years of life can be associated with lower lung function and a higher risk of childhood asthma.

The new study, led by Erasmus University in Rotterdam, The Netherlands, showed that the infants with the highest weight gain velocity and body mass index had lower lung function at 10 years of age.

Specifically, these children had a lower function related to the smaller airways in relation to their total lung volume.

The study also found that “the later the children reached their peak body mass index, the better their lung function and, in the case of boys, the lower the risk of asthma”, said lead author Maribel Casas, researcher at the varsity.

BMI, Asthma Risk
Asthma Medicine, Pixabay

“These results confirm that early childhood growth plays an important role in lung development,” Casas added.

Although no relationship between height and weight growth and the risk of asthma was observed, this disproportionate development of lung function could be a risk factor for the development of respiratory disease, the researchers said.

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For the study, published in the journal Thorax, the team tracked 4,435 children in the Netherlands from birth until 10 years of age.

The participants’ weight and height were measured multiple times during the first three years of life.

The team examined whether early childhood growth patterns — ascertained by taking repeated weight and height measurements during the first three years of the child’s life — affected respiratory health at the age of 10 years. (IANS)

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Flavoured E-Cigarettes Affect Airways, Worsen Asthma

Certain flavoured e-cigarettes, even without nicotine, may change how airways, affected by an allergic disease, function, thus worsening the severity of asthma

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e-cigarettes, flavoured, asthma, airways
A flavour multipack for the Juul vaping device. Sweet-flavored electronic cigarettes promote youth vaping. Wikimedia Commons

Certain flavoured e-cigarettes, even without nicotine, may change how airways, affected by an allergic disease, function, thus worsening the severity of diseases such as asthma, say researchers.

For the first time, a model of asthma was used to investigate the effect of a range of popular e-cigarette flavours, with and without nicotine.

“This is especially important for those with respiratory disease, whom are vulnerable to the effects of smoking,” Dr Chapman said.

“The majority of e-cigarette smokers use flavoured liquids but there is some evidence that flavour additives can be toxic when inhaled,” said Dr David Chapman from from the University of Technology Sydney (UTS).

The use of e-cigarettes has dramatically increased in the past few years, especially among younger smokers globally.

e-cigarettes, flavoured, asthma, airways
The U.S. Centers for Disease Control and Prevention (CDC) said Friday that they were investigating 215 cases of a serious lung disease possibly related to the use of e-cigarettes. VOA

Despite the suggestion they are a healthier alternative to tobacco cigarettes, there is a lack of evidence in both animal studies and human data on the effect of e-cigarettes on lung function.

The researchers found that some flavoured e-cigarettes, even in the absence of nicotine, can worsen disease severity.

“The exact effects on features of asthma were dependent upon the specific flavour, suggesting not all flavoured e-cigarettes will have the same consequences on lung health,” Dr Chapman said in the study published in Scientific Reports.

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In this study, the flavour Black Licorice exaggerated airway inflammation whereas Cinnacide had the opposite effect, suppressing airway inflammation.

The researchers didn’t analyse the liquids directly, to confirm what they contained, however there is evidence from previous research that flavours categorised as “buttery/creamy” and “cinnamon”, which likely include “Banana Pudding” and “Cinnacide”, respectively, are toxic.

Caution should be taken in promoting the use of flavoured e-cigarettes to patients with respiratory disease such as asthma and that policy makers should consider restricting the use of flavoured e-cigarettes, the team added. (IANS)