Never miss a story

Get subscribed to our newsletter

Using genetic techniques, scientists engineered the bacteria into a probiotic. Wikimedia Commons
  • Colorectal cancer is the third most common cancer worldwide.
  • The broccoli extracts can now be used to reduce the tumour size and terminate cancer.
  • Scientists have created a probiotic which will get cancer cells to kill themselves.

Researchers have developed a cocktail of bacteria and cruciferous vegetables that can potentially turn into a targeting system that seeks out and kills colorectal cancer cells.

Colorectal cancer is the third most common cancer worldwide, after lung and prostate cancer.

Although the 5-year survival rates for earlier stages of this cancer are relatively good, at later stages survival goes down and the risk of cancer recurrence goes up considerably.

Broccoli can help reduce bowel cancer.

Thus researchers, from the National University of Singapore, developed a mixture of engineered probiotics with a broccoli extract or water containing the dietary substance.

This mixture killed more than 95 percent of colorectal cancer cells in a dish.

Further, the probiotics-veggie combination also reduced tumour numbers by 75 percent in mice with colorectal cancer.

However, the mixture had no effect on cells from other types of cancer such as breast and stomach cancer.

These probiotics could be used as prevention and to clean up the cancer cells remaining after surgical removal of tumours, the researchers said.

“One day, colorectal cancer patients may be able to take the probiotics as a dietary supplement along with broccoli to prevent colorectal cancer or to reduce recurrence after cancer surgery,” said lead author Chun-Loong Ho from the varsity.

Broccoli, when used as a dietary supplement, can help reduce the risk of cancer. Image source:

For the study, published in the journal Nature Biomedical Engineering, the team developed a cancer-targeting system by engineering a form of E.coli Nissle — a harmless type of bacteria found in the gut.

Then using genetic techniques, they engineered the bacteria into a probiotic that attached to the surface of colorectal cancer cells and secreted an enzyme to convert a substance found in broccoli, into a potent anticancer agent.

The idea was for the cancer cells in the vicinity to take up this anticancer agent and be killed. IANS


Photo by Mike Enerio on Unsplash

Fireworks light up the night sky

Everyone loves firecrackers, even the most environment-friendly advocates cannot hide their joy when they see these delightful lights colour the skies. India celebrates Diwali in the true spirit of her culture and heritage by spraying the navy-blue skies with sparkling hues of gold, silver, red, and green. Firecrackers are not just a tradition in this country, they are a legacy.

The original connotation one makes with fireworks in China. The elaborate Chinese celebrations with dragons and zapping firecrackers have left their mark in human memory, but the use of fireworks is not limited to heralding the Chinese New Year. All over the world, fireworks have come to symbolise the ultimate celebration. During Diwali in India, this spirit is re-ignited every year.

Keep Reading Show less

A visitor looks at statues of the 'Royal treasures of Abomey kingdom' on display at the Musee du quai Branly in Paris on Sept. 10, 2021, part of 26 artworks set to be restituted to Benin later in the year.

PARIS — In a decision with potential ramifications across European museums, France is displaying 26 looted colonial-era artifacts for one last time before returning them home to Benin.

The wooden anthropomorphic statues, royal thrones and sacred altars were pilfered by the French army in the 19th century from Western Africa.

Keep Reading Show less

Logs cut from virgin Amazon rain forest are placed in a pile, in Brazil's northeastern Amazon region, February 11, 2008.

GENEVA — The battle to stem climate change may be lost as new information indicates the Amazon rain forest is turning from a carbon sink – or area that absorbs CO2 – into a source of carbon dioxide, the World Meteorological Organization warns.

The latest edition of the WMO's Greenhouse Gas Bulletin reports emissions of carbon dioxide, methane, and nitrous oxide once again broke all records last year.

Keep reading... Show less