Tuesday February 25, 2020

The All New Vaccine Will Eliminate HPV Infection, Claims Study

Harper also noted TS is different from Gardasil9, the vaccine given to prevent HPV infection. While Gardasil9 prevents HPV infection from occurring, TS clears tissue infected with it. 

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HPV
While "the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV", Harper said, adding the new vaccine "actually treats the cause of the disease, which is HPV". VOA

A new experimental immune-based vaccine has cleared human papillomavirus (HPV) in a third of women with cervical cancer precursors, according to clinical trial results.

The therapeutic vaccine, called Tipapkinogen Sovacivec (TS), injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraepithelial neoplasia (CIN).

HPV is a common sexually transmitted infection and causes warts in the body.

Doctor
While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”. VOA

The vaccine eliminated both precancerous skin growth in the cervix, and underlying HPV infection in a third of women enrolled in the clinical trial, according to the report in the journal Gynecologic Oncology.

“There are few products trying to cure women with an HPV infection,” said Diane Harper, professor at the University of Michigan. “It’s exciting. This is the first time we’ve seen something with this success rate and that is relatively easy to implement,” Harper said.

The study enrolled 192 women, diagnosed with precancerous skin growths, randomising 129 to receive the vaccine and 63, placebo.

Women were given three shots in thighs, one per week. Six months later, the women were treated with standard surgical procedures and the removed tissue was examined. As many as 15-36 per cent of those who were vaccinated saw their more severe precancerous skin growths eliminated, but none in the placebo group.

Doctor
While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”. VOA

While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”.

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Harper also noted TS is different from Gardasil9, the vaccine given to prevent HPV infection. While Gardasil9 prevents HPV infection from occurring, TS clears tissue infected with it.

The researchers envision testing TS for several other types of cancer, including head, neck and anal cancer, that are linked to HPV. (IANS)

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Here’s Why Surgery Can be an Effective Way To Overcome Obesity at an Early Age

According to the researchers, for many diseases, early treatment is advantageous, but individuals with early-onset obesity have often had their disorder for a long time before bariatric surgery is considered

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Obesity
According to the researchers, for many diseases, early treatment is advantageous, but individuals with early-onset obesity have often had their disorder for a long time before bariatric surgery is considered. Pixabay

 Researchers have found that surgical treatment of obesity is as effective for individuals who developed the disorder early, by the age of 20, as for those who have developed obesity later in life.

The results, published in the journal Diabetes Care, are based on data from the Swedish Obese Subjects (SOS) study.

For the fndings, the researchers covered a total of 4,026 adult individuals who had developed obesity. Half of them had undergone bariatric surgery and the other half were a control group.

“We were somewhat surprised at the results. Since the group that had already developed obesity by the age of 20 had been exposed to obesity and its risks for longer periods, we’d expected that bariatric surgical treatment in these participants would be less effective in terms of weight loss and obesity-related sequelae than in the other group. But it wasn’t like that,” said study researcher Johanna Andersson Assarsson from University of Gothenburg in Sweden.

Each of the groups was divided into three subgroups, based on the participants’ body mass index (BMI) at age 20: those of normal weight, those who were overweight, and those with obesity.

The researchers then investigated whether there was any difference in the effects of bariatric treatment for obesity among those who had developed the disorder before age 20, compared with those who developed it later in life.

“On the contrary, the group with obesity at age 20 lost a little bit more weight after the operation, and there was no difference in effects on diabetes or its complications, cardiovascular disease or cancer, compared with individuals who developed obesity later in life,” Assarsson said.

Slimming, The Weight Of The, Health, Lifestyle
Researchers have found that surgical treatment of obesity is as effective for individuals who developed the disorder early, by the age of 20, as for those who have developed obesity later in life. Pixabay

According to the researchers, for many diseases, early treatment is advantageous, but individuals with early-onset obesity have often had their disorder for a long time before bariatric surgery is considered.

It has sometimes been speculated that bariatric surgical treatment would be less effective in these individuals because of their longer exposure to the adverse health effects of obesity.

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“Here, we show that’s not the case. And we think it’s important that this information reaches people considering bariatric surgery for obesity and also health professionals who treat patients with obesity,” Assarsson said. (IANS)