Saturday January 18, 2020

The All New Vaccine Will Eliminate HPV Infection, Claims Study

Harper also noted TS is different from Gardasil9, the vaccine given to prevent HPV infection. While Gardasil9 prevents HPV infection from occurring, TS clears tissue infected with it. 

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HPV
While "the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV", Harper said, adding the new vaccine "actually treats the cause of the disease, which is HPV". VOA

A new experimental immune-based vaccine has cleared human papillomavirus (HPV) in a third of women with cervical cancer precursors, according to clinical trial results.

The therapeutic vaccine, called Tipapkinogen Sovacivec (TS), injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraepithelial neoplasia (CIN).

HPV is a common sexually transmitted infection and causes warts in the body.

Doctor
While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”. VOA

The vaccine eliminated both precancerous skin growth in the cervix, and underlying HPV infection in a third of women enrolled in the clinical trial, according to the report in the journal Gynecologic Oncology.

“There are few products trying to cure women with an HPV infection,” said Diane Harper, professor at the University of Michigan. “It’s exciting. This is the first time we’ve seen something with this success rate and that is relatively easy to implement,” Harper said.

The study enrolled 192 women, diagnosed with precancerous skin growths, randomising 129 to receive the vaccine and 63, placebo.

Women were given three shots in thighs, one per week. Six months later, the women were treated with standard surgical procedures and the removed tissue was examined. As many as 15-36 per cent of those who were vaccinated saw their more severe precancerous skin growths eliminated, but none in the placebo group.

Doctor
While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”. VOA

While “the surgical procedure removes all the tissue that is headed towards cancer, it does not remove all the HPV. You still have HPV”, Harper said, adding the new vaccine “actually treats the cause of the disease, which is HPV”.

Also Read: Large Democrats Already Targetting Trump for 2020 US Presidential Election

Harper also noted TS is different from Gardasil9, the vaccine given to prevent HPV infection. While Gardasil9 prevents HPV infection from occurring, TS clears tissue infected with it.

The researchers envision testing TS for several other types of cancer, including head, neck and anal cancer, that are linked to HPV. (IANS)

Next Story

Researchers Develop AI Tool To Detect Mental Health Issues

Tracking changes in clinical states is important to detect if there is a change that shows whether the condition has improved or worsened that would warrant the need for changing treatment

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The USC Signal Analysis and Interpretation Lab (SAIL), which has long applied artificial intelligence (AI) and machine learning to identify and classify video, audio and physiological data, partnered with researchers to analyse voice data from patients being treated for serious mental illnesses. Pixabay

Researchers, including one of Indian-origin, have developed an artificial intelligence (AI) tool that can accurately detect changes in clinical states in voice data of patients with bipolar, schizophrenia and depressive disorders as accurately as attending doctors.

“Machine learning allowed us to illuminate the various clinically-meaningful dimensions of language use and vocal patterns of the patients over time and personalised at each individual level,” said Indian-origin researcher and study senior author Shri Narayanan from University of Southern California (USC) in the US.

The USC Signal Analysis and Interpretation Lab (SAIL), which has long applied artificial intelligence and machine learning to identify and classify video, audio and physiological data, partnered with researchers to analyse voice data from patients being treated for serious mental illnesses.

For the results, the researchers used the ‘MyCoachConnect’ interactive voice and mobile tool, created and hosted on the Chorus platform to provide voice diaries related to their mental health states.

SAIL team then collaborated with researchers to apply artificial intelligence to listen to hundreds of voicemails using custom software to detect changes in patients’ clinical states. According to the study, the AI was able to match clinicians’ ratings of their patients.

Tracking changes in clinical states is important to detect if there is a change that shows whether the condition has improved or worsened that would warrant the need for changing treatment, the researchers said.

AI
Researchers, including one of Indian-origin, have developed an artificial intelligence (AI) tool that can accurately detect changes in clinical states in voice data of patients with bipolar, schizophrenia and depressive disorders as accurately as attending doctors. Pixabay

This project builds on SAIL’s body of work in behavioural machine intelligence to analyse psychotherapy sessions to detect empathy of addiction counselors-in-training in order to improve their chances of better outcomes, in addition to the Lab’s work analysing language for cognitive diagnoses and legal processes.

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“Our approach builds on that fundamental technique to hear what people are saying about using the modern AI. We hope this will help us better understand how our patients are doing and transform mental health care to be more personalised and proactive to what an individual needs,” said study lead author Armen Arevian. (IANS)