Saturday February 16, 2019

HPV Vaccines Are Effective, Especially For Teens

The Cochrane research pooled data and results from 26 studies involving more than 73,000 women across all continents over the last eight years.

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She noted that some campaign groups have expressed concern about HPV vaccines, but said this review had found no evidence to support claims of increased risk of harm.
HPV Vaccine i effective on teenage girls, Pexels

Vaccines designed to prevent infection with human papillomavirus (HPV) are effective in protecting against pre-cancerous cervical lesions in women, particularly in those vaccinated between age 15 and 26, according to a large international evidence review.

The research by scientists at the scientific network the Cochrane Review also found no increase in the risk of serious side effects, with rates of around 7 percent reported by both HPV-vaccinated and control groups.

“This review should reassure people that HPV vaccination is effective,” Jo Morrison, a consultant in gynecological oncology at Britain’s Musgrove Park Hospital, told reporters at a briefing about the review’s findings.

She noted that some campaign groups have expressed concern about HPV vaccines, but said this review had found no evidence to support claims of increased risk of harm.

HPV is one of the common sexually transmitted diseases. Most infections do not cause symptoms and go away on their own, but when the immune system does not clear the virus, persistent HPV infection can cause abnormal cervical cells.

Drugmakers GlaxoSmithKline and Merck make vaccines that protect against HPV.
A girls getting vaccine, VOA

These pre-cancerous lesions can progress to cervical cancer if left untreated. HPV is a leading cause of cancer deaths among women worldwide, according to the World Health Organization.

Drugmakers GlaxoSmithKline and Merck make vaccines that protect against HPV.

The Cochrane research pooled data and results from 26 studies involving more than 73,000 women across all continents over the last eight years.

The researchers found that in young women who tested negative for HPV, vaccination reduced the risk of developing precancer. About 164 out of every 10,000 women who got placebo developed cervical pre-cancerous lesions, compared with two out of every 10,000 who were vaccinated.

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Looking more broadly across all women in the studies, regardless of whether they had previously had HPV or not, the vaccines were found to be slightly less effective, but still reduced the risk of cervical precancer from 559 per 10,000 to 391 per 10,000.

Experts not directly involved in the review said its findings were robust and important.

“This intensive and rigorous Cochrane analysis … provides reassuring and solid evidence of the safety of these vaccines in young women,” said Margaret Stanley, a specialist in the pathology department at Cambridge University. “It reinforces the evidence that preventing infection by vaccination in young women … reduces cervical precancers dramatically.” (VOA)

 

Next Story

As Per Study, High-Risk HPV Lead to Increased CVD

For the study, researchers included 63,411 women aged 30 or older without CVD.

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Obesity leads to high CVB in women.
women with obesity were nearly two-thirds more likely to develop CVD. Pixabay

While human papillomavirus (HPV) have been linked to cancer, infection with high-risk strains of the virus might also increase the fear of cardiovascular disease (CVD), especially among women with obesity or other cardiovascular problems, according to a new research.

Certain strains of HPV are considered high risk because they can increase the probability of vaginal, vulvar, penile, mouth, throat and cervical cancers.

The study showed that women with high-risk HPV were 22 per cent more likely than uninfected women to develop cardiovascular disease.

High risk HPV contributes to CVD problems.
HPV are considered high risk as they develop CVD disease. Pixabay

In addition, women with obesity were nearly two-thirds more likely to develop CVD and those with metabolic syndrome and high-risk HPV were nearly twice as likely to develop the disorder, showed results published in Circulation Research: Journal of the American Heart Association.

Conversely, slightly more than 7 per cent of the women without CVD developed high-risk HPV infections.

Interestingly, women who smoked, consumed alcohol and reported being physically active were also more likely to have high-risk HPV. In contrast, higher education – college degree or more – was associated with a decreased likelihood of having high-risk HPV.

 

Fear of increased CVD disease is higher in obese women.
Women with obesity faces higher chances of CVD disease. Pixabay

“A better understanding of high-risk HPV as a risk factor for cardiovascular disease and possible combined effects of high-risk HPV, obesity and metabolic syndrome in increasing cardiovascular disease risk may help improve preventive strategies and patient outcomes,” said Seungho Ryu, Professor at Sungkyunkwan University in South Korea.

Further studies are required to identify specific high-risk HPV genotypes that may contribute to cardiovascular disease and to examine whether vaccine strategies to reduce high-risk HPV infection for cancer prevention may also help reduce CVD, suggested the study.

ALSO READ: Keep Obesity At Bay With Flaxseeds

For the study, researchers included 63,411 women aged 30 or older without CVD. (IANS)