Wednesday January 22, 2020

Researchers Develop Hydrogel to Treat Infections in Wound

New hydrogel to prevent infections in wounds developed

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wounds
The ability to effectively heal wounds is key for our survival in evolutionary terms. Pixabay

Researchers have developed a new hydrogel based on the body’s natural peptide defence as it has been shown to prevent and treat infections in wounds.

The formulation kills multi-resistant bacteria, something that is increasing in importance with antibiotic resistance growing globally, said the study, published in the journal Science Translational Medicine.

“The ability to effectively heal wounds is key for our survival in evolutionary terms. There are peptides in wounds that defend against bacteria and prevent their toxins from causing inflammation,” said study researcher Artur Schmidtchen, Professor at Lund University in Sweden.

“The gel is based on these natural defence mechanisms and has had a dual effect – by both preventing as well as treating wound infections,” Schmidtchen added.

wounds
The gel is based on these natural defence mechanisms and has had a dual effect – by both preventing as well as treating infections in wounds. Pixabay

According to the researchers, antibiotics and antiseptics kill the bacteria but do not affect the subsequent harmful inflammatory process.

“Another problem is that the active substances in today’s antiseptic wound treatment often are toxic and harmful to the environment. We have not seen this with our active substance, and it also kills multi-resistant bacteria,” Schmidtchen said.

The wound gel is not only antibacterial, it also has an immunosuppressive effect.

The researchers have previously shown that the peptides in the gel can inactivate so-called lipopolysaccharides (LPS), that are found in cell walls of bacteria, and that trigger an inflammatory reaction.

The reaction is an essential part of our immune system as we quickly respond to and fight bacteria.

Also Read- Tips For a Happy and Healthy 2020

“However, severe and uncontrolled inflammation inhibits wound healing, and it is very interesting to see that the gel lowers the inflammatory response within 24 hours of the treatment, and then further reduces the bacterial levels over a period of three to four days,” Schmidtchen added.

We have designed a whole new type of treatment that uses nature’s own principles by not only killing bacteria but also acting as an immune-modulatoring”, said Indian-origin researcher and study co-author Manoj Puthia. (IANS)

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Promotional E-Cigarettes Posts on Instagram Outnumber Anti-Vaping Content: Study

E-cigarette popular on Instagram despite anti-vaping content

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e-cigarettes
Despite "The Real Cost" awareness campaign launched by the US Food and Drug Administration (FDA) in 2018, nearly one third of American teenagers are estimated to use e-cigarettes. Pixabay

Promotional e-cigarettes posts on popular photo-sharing platform Instagram outnumber anti-vaping content 10,000 to one, according to a new study and health news.

Despite “The Real Cost” awareness campaign launched by the US Food and Drug Administration (FDA) in 2018, nearly one third of American teenagers are estimated to use e-cigarettes, the researchers said.

The study, published in the journal Frontiers in Communication, highlights the limited impact of the FDA campaign, while also using deep learning – an artificial intelligence method – to better understand the marketing tactics used by vaping companies.

“US public health officials have been calling vaping among youth an epidemic and have been putting a lot of effort into trying to stop this epidemic by introducing #TheRealCost anti-vaping campaign but this stark imbalance in the volume of posts has caused the FDA message to be overwhelmed by marketing from the vaping brands,” said study researcher Julia Vassey from University of California in the US.

e-cigarettes
Many teenagers continue to view e-cigarettes as healthier than conventional cigarettes, but vaping is associated with inflammation, reduced immune responses and breathing troubles. Pixabay

Many teenagers continue to view e-cigarettes as healthier than conventional cigarettes, but vaping is associated with inflammation, reduced immune responses and breathing troubles, the study said.

To further understand how vaping is perceived on social media, research team collected 245,894 Instagram posts spanning from before and after the #TheRealCost campaign launch.

The team also conducted interviews with five vaping influencers and eight college-age social media users. “We focused on Instagram because the vaping influencers we interviewed for this study identified Instagram as their most important social media marketing platform,” Vassey explained.

“Based on the results, the FDA anti-vaping campaign is not very popular and we saw Instagram user comments disputing the FDA claims of damaging health effects from nicotine and calling the campaign propaganda,” Vassey added.

Also Read- Drugs That Treat Arthritis in Dogs Can Kill Cancer Cells: Study

In contrast to the FDA’s intentions, the study found that vaping posts received nearly three times more “likes” after the campaign launch. They also found that there were six times as many posts that had greater than 100 likes.

According to the researchers, participants in the focus groups suggested that the anti-vaping campaign promoted scare tactics rather than offering guidance on how to quit vaping. (IANS)