Saturday, October 31, 2020
Home Life Style Health & Fitness Increased Risks of Death in Patients With Fatty Liver Disease

Increased Risks of Death in Patients With Fatty Liver Disease

Fatty Liver Disease May Lead to Death

In a major study, researchers have found an increased risk of death in patients with non-alcoholic fatty liver disease (NAFLD) and advanced fibrosis or cirrhosis.

The study, published in the journal Gut, shows that mortality increases with disease severity, but even mild fatty liver disease is linked to higher mortality.

Small clinical studies have demonstrated that among patients with NAFLD, advanced liver fibrosis is the most important histological predictor of mortality, but until now, population-level data have been missing from cohorts with liver histology.

Follow NewsGram on Instagram to keep yourself updated.

“This is the first nationwide cohort study with detailed liver histology data to confirm that NAFLD contributes to an increased risk of all-cause mortality,” said study first author Tracey G Simon from the Massachusetts General Hospital in the US.

Non-alcoholic fatty liver disease is often caused by obesity and affects nearly 25 percent of the US and European adults. It represents the most common cause of chronic liver disease in Western countries.

Fatty Liver
Patients with NAFLD had a 93 percent increased risk of all-cause mortality, but the numbers varied with disease severity. Pinterest

For the current results, the research team matched 10,568 individuals with biopsy-confirmed NAFLD to general population controls through Sweden’s comprehensive, nationwide registers.

They found that all stages of NAFLD were associated with excess mortality risk, even early stages of the disease.

This risk was driven primarily by deaths from extra-hepatic cancer and cirrhosis, while the risks of cardiovascular mortality or hepatocellular carcinoma (HCC) mortality were relatively modest.

Patients with NAFLD had a 93 percent increased risk of all-cause mortality, but the numbers varied with disease severity.

Also Read: Chronic Jet Lag Makes Tumor Cells More Favorable

The risk increased progressively from the mildest form of NAFLD (simple steatosis), to non-fibrotic steatohepatitis (NASH), to non-cirrhotic fibrosis, and to severe NAFLD with liver cirrhosis.

These findings should be used to develop more targeted interventions designed to reduce mortality, in patients with NAFLD,” Simon said. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,779FollowersFollow

Most Popular

Menstrual Dysfunction Prevalent in Young Athletes

Researchers, including one of Indian-origin, have found that menstrual dysfunction is more prevalent in young athletes than among non-athletes of a similar age. The study,...

Spinning Keeps You Energized and Your Mind Focused

One of the most popular cardio work-outs in North America, Latin America, Europe, and other parts of Asia, and a current global phenomenon, rhythm-based...

Change in Indian Healthcare Industry is Need of the Hour

With all the chaos created due to the pandemic, a change in the Indian healthcare industry is the need of the hour, feels Anita...

Food Habits to Follow if You Have Arthritis

Arthritis is an autoimmune disease that affects joint and bone pain. It could be a problem or a matter of concern, If not taken...

New Mask Aiming to Make Wearer Less Infectious

People wear face masks to protect others -- not merely to protect themselves. With this in mind, researchers have developed a new concept for...

Cognitive Disorders Increase Risks of Developing Severe COVID

Researchers have claimed that dementia and other cognitive disorders now appear to be the risk factors for developing severe COVID-19. The findings, published in the...

Localized Content Driving New Customers in Amazon Prime Video

Riding on localized content being churned out in countries like India, the number of Prime members who stream Prime Video grew by more than...

Cheerful People Likely to Experience Less Memory Decline

People who feel enthusiastic and cheerful -- what psychologists call "positive affect" -- are less likely to experience memory decline as they age, say...

Recent Comments