Sunday December 15, 2019

India: Takeda Launches Enzyme Replacement Therapy for ‘Lysosomal Storage Disorders’ (LSD)

To address these, Takeda brings to the market Idursulfase for Hunter Syndrome

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Under 'lysosomal storage disorders', India has been recording prevalence of Hunter Syndrome. Pixabay

Expanding its portfolio of rare disease therapies in India, global bio-pharmaceutical company Takeda on Monday announced launch of the enzyme replacement therapy for ‘lysosomal storage disorders’ (LSD).

“Under ‘lysosomal storage disorders’, India has been recording prevalence of Hunter Syndrome, Gaucher Disease and Fabry Disease. To address these, Takeda brings to the market Idursulfase for Hunter Syndrome, Velaglucerase Alpha for Gaucher Disease and Agalsidase Alfa for Fabry Disease,” the company said in a statement.

Fabry disease interferes with the body’s ability to break down a specific fatty substance (globotriaosylceramide or Gb3). Over 8,000-10,000 people worldwide have been affected by the disease.

Takeda, Enzyme Replacement, Therapy
Expanding its portfolio of rare disease therapies in India, global bio-pharmaceutical company Takeda on Monday announced launch of the enzyme replacement therapy for ‘lysosomal storage disorders’ (LSD). Pixabay

Hunter Syndrome is a serious genetic disorder that interferes with the body’s ability to break down specific mucopolysaccharides, also known as glycosaminoglycans or GAGs. It primarily affects males.

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Gaucher is a rare inherited metabolic condition that affects approximately one in 100,000 people. Patients with type-1 Gaucher disease may experience varying symptoms and degrees of disease severity, making it difficult to diagnose. (IANS)

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Mindfulness can Reduce Opioid Cravings, Study Says

Mindfulness is the meditative practice of focusing on the present moment and accepting one's thoughts, feelings and bodily sensations, without judgement.

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Mindfulness
Study Says, People suffering from opioid addiction and chronic pain might have fewer cravings and less pain if they use both Mindfulness techniques and Medication for opioid dependence. Pixabay

People suffering from opioid addiction and chronic pain might have fewer cravings and less pain if they use both mindfulness techniques and medication for opioid dependence, a new study said.

Mindfulness is the meditative practice of focusing on the present moment and accepting one’s thoughts, feelings and bodily sensations, without judgement.

According to the researchers, for many of those with opioid addictions who experienced chronic pain, anxiety and depression, methadone maintenance and mindfulness-based, non-drug interventions were promising treatments.

“Methadone maintenance therapy (MMT) has been an effective form of medication treatment for opioid use disorder,” said Nina Cooperman, Associate Professor at Rutgers University in the US.

“However, nearly half of individuals on MMT continue to use opioids during treatment or relapse with six months,” Cooperman said.

The study, published in the journal Drug and Alcohol Dependence, examined the effects of mindfulness and methadone therapy on 30 patients with opioid addiction and chronic pain.

Mindfulness
Mindfulness is the meditative practice of focusing on the present moment and accepting one’s thoughts, feelings and bodily sensations, without judgement. Pixabay

The findings showed that those who received methadone and a mindfulness training-based intervention were 1.3 times better at controlling their cravings and had significantly greater improvements in pain, stress and positive emotions, even though they were aware of more cravings than those who only received standard methadone treatment and counselling.

The researchers said that mindfulness-based interventions could help people dependent on opioids increase their self-awareness and self-control over cravings and be less reactive to emotional and physical pain.

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Individuals with an opioid addiction could also be taught to change their negative thoughts and savour pleasant events, which might help them to regulate their emotions. (IANS)