Thursday June 21, 2018

Indian-origin researcher working to beat ‘superbugs’

0
//
82
Republish
Reprint

Researchers, including one of the Indian-origin, have developed novel peptide-like analogs or peptoids that have the similar antimicrobial properties as peptides but more robust.

The discovery paves the way for the creation of new generation antibiotics that can defeat the so-called multi-drug resistant bacteria “superbugs”.

Like proteins, peptides are are chains of amino acids that participate in the metabolic system of living organisms and the immune system.

They are the first line of defense against a broad range of pathogens and are released by the body in the earliest stage of infection.

These peptides are attractive antimicrobials. However, they degrade in the body and have the short half-life.

Rinki Kapoor along with her PhD advisor and professor Annelise Barron of Stanford University studied novel mimics of antimicrobial peptides or peptoids for their antibacterial activity against multi-drug resistant bacteria, also known as superbugs.

In one of their studies, they showed that peptoids kill resistant Pseudomonas aeruginosa — one of the leading bug causing hospital associated infections.

The group synthesised seven different peptoids and compared their activity with three different antibiotics.

In a separate study, Kapoor and Barron also revealed that peptoids kill resistant Mycobacteria — bacteria responsible for causing Tuberculosis, a leading cause of death worldwide. In this study, published in the journal of antimicrobial agents and chemotherapy (AAC), they evaluated the efficacy of six different peptoids against Mycobacteria.

“These molecules are currently under research and development and merit further studies to investigate their potential as the new class of drugs for treating resistant bacterial infections,” Kapoor told IANS in a statement.(IANS)

Click here for reuse options!
Copyright 2016 NewsGram

Next Story

Indian design schools Are Influenced By Global education

The diversity and the demographics of everything is making the world come closer

0
Indian design schools Are Influenced By Global education
Indian design schools Are Influenced By Global education, flickr

Ace designer Manish Malhotra, who is one of the chief mentors at the London School of Trends, says that global education is making a huge difference to all the design schools of India.

“It is making a difference overall not just to the design schools. Thanks to global education, global awareness the world is getting far more closer. Social media, travel and interactions with one another is playing a key role to make this happen,” he told IANS in a statement.

“The diversity and the demographics of everything is making the world come closer,” added Malhotra who has over 25 years of experience in styling up for Bollywood movies and has dressed the best in the glamour business.

London School of Trends offers an international Fashion and Interior Design curriculum curated and taught by globally renowned academics and industry leaders.

Manish Malhotra’s collections displayed at the Raj Mahal Jewellers India Couture Week 2014.
Manish Malhotra’s collections displayed at the Raj Mahal Jewellers India Couture Week 2014. flickr

Also read: ‘Intern Diaries’ To Feature Sonakshi, Anita Dongre, Manish Malhotra

They have a global presence with campuses in New York, Los Angeles, New Delhi and Mumbai. In India, they have Malhotra along with Producer-author Twinkle Khanna as their chief mentors for fashion and interior design, respectively. (IANS)

 

Next Story