Indo-Canadian actress Lisa Ray, a cancer survivor, has sent love and wishes to Bollywood actress Sonali Bendre, who revealed earlier this week that she has been diagnosed with a “high-grade cancer”. Sonali is currently undergoing treatment in New York.
The news about her health led a slew of film fraternity members to post heartfelt messages of support to Sonali and her family. Lisa, who calls herself a cancer graduate, tweeted on Saturday: “Dear Sonali Bendre, you are in my thoughts. Words often fall short and I’ve learned that okay, but I do want to send love.”
Lisa was in 2009 diagnosed with multiple myeloma, a cancer of the white blood cells known as plasma cells which produce antibodies. A year later, she announced that she was cancer-free, after a stem cell transplant. As multiple myeloma is incurable, she is not completely cured of the disease. (IANS)
While eating foods rich in omega-3 fatty acids, such as fatty fish, certain nuts and seeds, have been known to prevent heart diseases and arthritis, a new research, led by one of Indian-origin, showed that omega-3 fatty byproducts may also have anti-cancer effects.
The new study, led by Aditi Das from University of Illinois at Urbana-Champaign, US, showed that when the human body metabolises omega-3 fatty acids, it produces a class of molecules called endocannabinoid epoxides, or EDP-EAs. These have anti-inflammatory properties and can inhibit cancer’s growth and spread.
The EDP-EAs have similar properties to cannabinoids found in marijuana — but without the psychotropic effects — and they target the same receptor in the body that cannabis does.
“We have a built-in endocannabinoid system which is anti-inflammatory and pain-reducing. Now we see it is also anti-cancer, stopping the cells from proliferating or migrating,” said study leader Aditi Das from University of Illinois at Urbana-Champaign.
“These molecules could address multiple problems: cancer, inflammation and pain,” Das added.
For the study, published in the Journal of Medicinal Chemistry, the team studied the effect of the molecule in mice with tumours of osteosarcoma — a bone cancer that is not only painful but also difficult to treat.
The results showed that the endocannabinoids slowed the growth of tumours and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death.
The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market. But, the compounds slowed tumour growth by inhibiting new blood vessels from forming to supply the tumour with nutrients. They also prevented interactions between the cells, and most significantly, they appeared to stop cancerous cells from migrating.
While dietary consumption of omega-3 fatty acids can lead to EDP-EAs, for those with cancer, something concentrated and fast acting is needed, Das said.
“That’s where the endocannabinoid epoxide derivatives come into play – you could make a concentrated dose of the exact compound that’s most effective against the cancer. You could also mix this with other drugs such as chemotherapies,” she added. (IANS)