Tuesday January 23, 2018
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Indo-US experts developing solar-powered oral cancer detector for remote areas

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Kolkata: Researchers in India and the US are testing a handy solar-powered device for early detection of oral cancer which could be integrated with mobile technology, enabling faster and accurate diagnostics in rural areas.

Designed by the Beckman Laser Institute (BLI), University of California-Irvine (UCI) and the Mazumdar Shaw Cancer Centre (MSCC) in Bengaluru, the compact screening and diagnosing system – slightly larger than a shoe box – has been specially adapted for India, which has one of the highest rates of head and neck cancers in the world and accounts for the highest rate among women.

Its light-weight and user-friendly features mean even minimally educated healthcare workers in the field can apply it. The solar energy-driven device will capture images of the patient’s oral cavity and transmit them via a mobile phone to experts at the centre.

“India is the first country in which we are using the device – it was specifically designed to meet conditions and needs there. The final device will have a solar option,” Petra Wilder-Smith of BLI told a news agency in an email interaction.

Recognised as a pioneer in the application of optics and lasers in oral diagnosis, Wilder-Smith said the device is based on optical coherence tomography (OCT) – an imaging technology that is similar to ultrasound, except that it uses light (a laser). The screening will be in real-time and the patient will not be subjected to harmful radiation.

“The inexpensive, very small, robust portable diagnostic system for oral cancer based on OCT will be used to screen for oral cancer in the field by basic level healthcare workers in India, and a simple diagnostic algorithm will indicate further diagnostic and treatment needs for each individual,” said Wilder-Smith, director of dentistry at BLI.

Oral cancer is the most common cancer in India, accounting for 40 percent of all cancers overall and for over 50 percent of all cancers in some areas of the country.

It is also disturbing to note the spike in oral cancer in young adults.

“In the US, the oral cancer rate is also high, especially in African-Americans, older persons, and tobacco and alcohol users. It is particularly troubling that recently a trend has been observed worldwide towards an increased incidence of oral cancer among young adults,” informed Wilder-Smith, stressing on early detection.

Why the emphasis on the light-based technology?

Wilder-Smith said oral cancer and pre-cancer are currently diagnosed using a visual exam, which has a poor accuracy rate, and by surgical biopsy, which cannot be performed in the field by basic-level healthcare workers.

And since existing and emerging imaging-based diagnostic tools are too expensive, too fragile and difficult to operate in remote locations, head and neck oncologist M.A Kuriakose from MSCC, who is leading the venture in India, said the probe will be of immense value in low-resource settings in rural India, where visits to dentists are rare.

“It is being tested in MSCC Bengaluru. The validation phase is 12 months. We are also planning to incorporate the transmission of the laser image from remote location via a mobile phone. Once developed, one needs to get regulatory approvals before it can be made available for wider clinical use,” Kuriakose said.

With the fabrication cost goal estimated at lower than $5,000 (Rs.335,000), researchers say the subsequent models of the probe will be wireless and 3D scan-enabled.

“The experimental model costs about Rs.1.5 lakh (lower than that of existing commercial devices). However, the commercial product cost will be significantly lower,” Kuriakose told a news agency.

The project is funded by the National Institute of Health’s National Institute of Biomedical Imaging and Bioengineering, under the Indo-US collaborative programme. The Department of Biotechnology is also a funding partner, said Kuriakose.

The collaborators are also working in close consultation to thrash out a simple diagnostic algorithm which will indicate further diagnostic and treatment needs for each individual.

“Screening will identify whether a person needs to travel to a centre with higher levels of expertise in oral cancer for further tests and potential cancer therapy,” Wilder-Smith added.

(Sahana Ghosh, IANS)

(Picture credit:www.thehoopsnews.com)

 

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Colorectal Cancer Rising Among Younger Adults

Researchers note that rates of colorectal cancer have been falling since the 1980s.

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Colorectal Cancer rising among the young adults. Pixabay
Colorectal Cancer rising among the young adults. Pixabay
  • Latest research says young adults have higher chances of having colorectal cancer
  • Risk is higher in those born in 1990
  • The research also has stats for other kinds of cancer

Americans born in 1990 have double the risk of colon cancer and quadruple the risk of rectal cancer than those born around 1950, a new study suggests.

The study found that colorectal cancer is on the rise among young and middle-aged adults in their early 50s. Rectal cancer is growing particularly fast among people younger than 55, with 30 percent of diagnoses in people under 55.

“Trends in young people are a bellwether for the future disease burden,” said Rebecca Siegel, of the American Cancer Society and lead author of the study that appeared in the Journal of the National Cancer Institute.

Also Read : Battle against Cancer with these foods

The risk is more for people born in 1990 than those in 1950. Wikimedia commons
The risk is more for people born in 1990 than those in 1950. Wikimedia commons

“Our finding that colorectal cancer risk for millennials has escalated back to the level of those born in the late 1800s is very sobering. Educational campaigns are needed to alert clinicians and the general public about this increase to help reduce delays in diagnosis, which are so prevalent in young people, but also to encourage healthier eating and more active lifestyles to try to reverse this trend.”

Researchers note that rates of colorectal cancer have been falling since the 1980s with an even steeper decline in the past decade, which has been caused by more screening.

But they wanted to find out why some studies have shown a rising rate among people under 50 for whom screening is generally not done. For their study, researchers looked at cases of colorectal cancer in people over 20 from 1974 to 2013. There were 490,305 cases.

Cancer rate declined generally but increased in this particular age group. VOA
Cancer rate declined generally but increased in this particular age group. VOA

The data showed the rates of colon cancer initially decreased after 1974, but then grew by one or two percent from the mid-1980s to 2013 among adults aged 20 to 39. For people aged 40 to 54, the rates increased between .5 percent and one percent from the mid 1990s to 2013.

For rectal cancer, the increases were greater, with rates rising about three percent per year from 1974 to 2013 in adults aged 20 to 29. For adults between 30 and 39, there was a similar rise from 1980 to 2013. For adults between 40 and 54, rates increased by two percent from the 1990s to 2013.

Rates for adults older than 55 has been declining for about 40 years, researchers said.

Also Read : Immunotherapy : Allison’s Trials

Researchers say the results could change the age at which screening for colorectal cancer starts and cite 10,400 cases diagnosed in people in their 40s plus 12,800 cases in people in their early 50s.

“These numbers are similar to the total number of cervical cancers diagnosed, for which we recommend screening for the 95 million women ages 21 to 65 years,” Siegel said. VOA