Monday December 17, 2018

Newly Developed Inhaler to Treat Migraine Without Medicine, says Study

While 45 per cent people experienced an effect the first time, and that number rose to 78 per cent the second time

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Migraine
Migraines that affect vision may increase irregular heartbeat risk. Pixabay
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Some migraine patients can cut down on medication or stop using it completely by using a newly developed inhaler which changes the composition of the air we breathe, results of a clinical trial say.

Migraines occur as part of a chain reaction during which the veins in the brain contract and the blood cannot therefore supply the brain with sufficient oxygen, the researchers said.

In the study, the team from the Aarhus University in Denmark examined a small group of patients who suffer from migraine with aura, which is where they experience either sensory or visual disturbances before the painful headaches begin.

The novel inhaler slightly changes the body’s own molecules.

It utilises carbon dioxide and oxygen, which are the body’s natural molecules for mobilising its own defence against migraine attacks.

Migraine
Migraine is a risk factor for sudden sensorineural hearing loss — characterized by rapid loss of hearing in one or both ears, which may occur immediately or over the course of several days. Pixabay

“The inhaler expands the blood vessels that supply the brain with oxygen by up to seventy per cent and thereby stops the destructive chain reaction,” said Troels Johansen, from the varsity.

Johansen added that the effect of the treatment starts after a few seconds.

The results, published in the journal Cephalalgia, showed that the effect of the pain relief increased significantly with each use of the inhaler.

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While 45 per cent people experienced an effect the first time, and that number rose to 78 per cent the second time.

“The study shows some very significant physiological effects in the body,” Johansen said, adding that the team is now planning to conduct a large clinical trial that will also include migraine without aura and chronic migraine. (IANS)

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Migraine With Visual Aura May Increase Risk of Irregular Heartbeat

"Atrial fibrillation can be managed through medication, but many people do not realise that they have atrial fibrillation," Sen noted

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Migraine
Migraines that affect vision may increase irregular heartbeat risk. Pixabay

People who experience migraine with visual aura may have an increased risk of irregular heartbeat, and as a result stroke, say researchers including one of an Indian-origin.

Migraine with visual aura is when disturbances in vision occur right before the head pain begins. Those disturbances may include seeing wavy lines or flashes of light, or having blurry vision or blind spots.

With an irregular heartbeat called atrial fibrillation, the heart’s normal rhythm is out of sync. As a result, blood may pool in the heart, possibly forming clots that may go to the brain, causing a stroke.

The study suggested that atrial fibrillation may play a role in stroke in those with migraine with visual aura.

“It is important to note that people with migraine with aura may be at a higher risk of atrial fibrillation due to problems with the autonomic nervous system, which helps control the heart and blood vessels,” said Souvik Sen, from the University of South Carolina in the US.

Migraine
The study suggested that atrial fibrillation may play a role in stroke in those with migraine with visual aura.

For the study, published in the journal, Neurology, the team examined 11,939 people with an average age of 60 without prior atrial fibrillation or stroke were evaluated for headache.

The results revealed an estimated nine out of 1,000 people with migraine with aura suffer atrial fibrillation compared to seven out of 1,000 people with migraine without aura.

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The rate of stroke in the migraine with aura group was four out of 1,000 people annually compared to two out of 1,000 people annually in those with migraine without aura, and three of 1,000 people annually in those with no headache, the findings suggested.

“Atrial fibrillation can be managed through medication, but many people do not realise that they have atrial fibrillation,” Sen noted. (IANS)