Sunday January 21, 2018

Integrate National Plans to Eliminate TB by 2030: WHO

The WHO South East Asia Region includes India, Bangladesh, Bhutan, North Korea, Indonesia, Maldives, Myanmar, Nepal, Sri Lanka, Thailand and Timor-Leste

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India TB Outreach Work
A TB patient hopeful of being cured in India. Wikimedia
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New Delhi, Sep 11, 2017: The World Health Organisation (WHO) has told the South East Asian countries to integrate their national plans and mobilise and utilise resources efficiently to reach the Tuberculosis elimination target of 2030, a statement said on Sunday.

The WHO South East Asia Region includes India, Bangladesh, Bhutan, North Korea, Indonesia, Maldives, Myanmar, Nepal, Sri Lanka, Thailand and Timor-Leste.

Also Read: Malnutrition makes children susceptible to Tuberculosis: Experts 

The global health body said that there is a need for countries to identify the package of interventions best suited to their challenges — whether that means focusing on strengthening TB services, accelerating case detection or investing in research and development.

“All countries face unique challenges, meaning they should each adapt the regional and global strategies to their context,” said a statement issued by the WHO’s South East Asia Region Office.

“We must avoid taking one-size-fits-all approach, and must instead seek out and embrace tailored solutions that meet specific needs and challenges.”

The five-day 70th Regional Committee Session of WHO South East Asia Region concluded in Male on Sunday.

According to the global health body, by planning effectively and making smart, high-impact interventions, countries across the Southeast Asia Region can lift TB’s significant burden and end the disease as a public health threat once and for all.

Although the region accounts for approximately one quarter of the world’s population, it has nearly half the number of new TB cases and close to 40 per cent of TB deaths globally.

In recognition of TB’s outsized burden, accelerating progress towards the 2030 target — which requires a 90 per cent reduction in TB deaths and 80 per cent decrease in TB incidence — is now one of WHO South-East Asia Region’s flagship priority areas of work. (IANS)

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Vitamin C helps in treating Tuberculosis

Taken in diet with medication, it will enhance treatment

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TB is the leading killer of HIV-infected people. In South Africa, 73% of TB patients are HIV positive. Pixabay
TB is the leading killer of HIV-infected people. In South Africa, 73% of TB patients are HIV positive. Pixabay

Foods rich in Vitamin C (such as dark leafy greens, broccoli, kiwifruit and oranges) can enhance treatment and enable a faster recovery for people suffering from tuberculosis (TB), if taken along with regular medication.

TB is one of the world’s deadliest diseases, with one third of the global population infected. In 2016, it affected 10.4 million people around the world and caused 1.7 million deaths.

Vitamin C helps treating TB. Pexels
Vitamin C helps treating TB. Pexels

Findings

  • Giving Vitamin C — a powerful antioxidant that reduces oxidative stress to the body and also lowers cancer risk — with TB drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen.
  • The addition of Vitamin C to TB drug treatment potentiates the killing of bacterium Mycobacterium tuberculosis (MTB) and could shorten TB chemotherapy.
  • That’s important because treatment of drug susceptible TB takes six months, resulting in some treatment mismanagement, potentially leading to the emergence and spread of drug-resistant TB.

Vitamin C had no activity by itself, but in two independent experiments, the combination of Vitamin C with the first-line TB drugs, isoniazid and rifampicin, reduced the organ burdens faster than the two drugs without vitamin C, said Catherine J. Vilcheze, at the varsity.

“Vitamin C is known to be safe and our current mouse studies suggest that Vitamin C could enhance TB chemotherapy,” said lead investigator William R. Jacobs, from the Albert Einstein College of Medicine in New York.

TB is one of the world's deadliest diseases, with one third of the global population infected. Wikimedia commons
TB is one of the world’s deadliest diseases, with one third of the global population infected. Wikimedia commons

Methodology

  • The team treated MTB-infected mice with anti-TB drugs or vitamin C alone, or the drugs and vitamin C together.
  • Experiments in infected tissue cultures demonstrated similar results, shortening the time to sterilisation of the tissue culture by seven days.

The study was published in the journal Antimicrobial Agents and Chemotherapy. (IANS)