An Israeli study said on Sunday that fungal infections could be cured using bacteria found in the soil.
The researchers tried using bacillus subtilis bacteria, which naturally secrete substances that inhibit candida growth, according to the study published by the Israel Institute of Technology “Technion,” Xinhua reported.
The researchers developed a new model for drug therapy, which is a tiny “factory” where the bacteria inside it begin to produce the active substance.
The prevalence of fungal infections is on the rise due to the aging of the population, global warming and the increasing use of antibiotics.
The effectiveness of pills currently available for fungal infections is low due to side effects such as headaches and rash, and in some cases, life-threatening toxicity in the liver and kidneys.
Researchers have found that fatty tissues accumulate in the airway walls, particularly in people who are overweight or obese.
The study, published in the European Respiratory Journal, suggested that the fatty tissue alters the structure of people’s airways and this could be one reason behind the increased risk of asthma.
“Our research team studies the structure of the airways within our lungs and how these are altered in people with respiratory disease,” said the study’s author John Elliot from Sir Charles Gairdner Hospital in Australia.
“Looking at the samples of lungs, we spotted fatty tissue that had built up in the airway walls. We wanted to see if this accumulation was correlated with body weight,” Elliot said.
The researchers examined post-mortem samples of the lungs that had been donated for the research and stored in the Airway Tissue Biobank.
They studied samples from 52 people, including 15 who had no asthma, 21 who had the disease but died of other causes and 16 who died of asthma.
Using dyes to help visualise the structures of 1373 airways under a microscope, they identified and quantified any fatty tissue present.
They compared this data with each person’s body mass index (BMI).
The study showed that fatty tissue accumulates in the walls of the airways. The analysis revealed that the amount of fat present increases in line with increasing BMI.
“We’ve found that excess fat accumulates in the airway walls where it takes up space and seems to increase inflammation within the lungs,” said the study’s co-author Peter Noble.