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By Aishwarya Nag Choudhury
The demise of the former Indian president APJ Abdul Kalam is being mourned all over the nation. Popularly known as the ‘Missile man’ of India, Kalam was on a trip to Shillong when he passed away on Monday evening at the age of 83.
He was on his way to speak to the students of Indian Institute of Management Shillong (IIM- S). However, he collapsed while addressing the students around 6.30 pm and was immediately rushed to Bethany hospital, where he died at 7.45 pm.
While television screens, newspapers, and social media are overflowing with the news of Kalam’s demise, Srijan Pal Singh MD of Giving Light, author and advisor to APJ Abdul Kalam, who was travelling with the former president has written an account of his last day on his Facebook wall. Singh, who was a student of Kalam starts his tribute by saying “This is what I will be remembered for…”
Singh’s post recorded the activities of the former president on his last day. He wrote about the flight, and how he complimented Kalam on the color of his suit. “He was wearing a dark colored ‘Kalam suit’, and I started off complimenting, ‘Nice color!’ Little did I know that this was going to be the last color I will see on him.” wrote Singh. He gave an account of their travel, the two and a half hour car ride, and an exercise he prepared for the students after the speech.
For the past two days, Dr. Kalam was worried that time and again Parliament, the supreme institution of democracy, has been dysfunctional. He said, “I have seen two different governments in my tenure. I have seen more after that. This disruption just keeps happening. It is not right. I really need to find out a way to ensure that the parliament works on developmental politics.”
He then asked me to prepare a surprise assignment question for the students at IIM Shillong, which he would give them only at the end of the lecture. He wanted them to suggest three innovative ways to make the Parliament more productive and vibrant. Then, after a while he returned on it. “But how can I ask them to give solutions if I don’t have any myself.”
They also discussed the environment and the Punjab attacks during their ride. Kalam was concerned about a security personnel who had to stand throughout the journey in an open jeep and later personally thanked him. This, Singh said “was an experience from the beauty of his humility.”
On reaching the University, Singh recalls the president did not want to be late for the lecture. “Students should never be made to wait, he always said,” Singh wrote. “Two minutes into the speech, sitting behind him, I heard a long pause after completing one sentence. I looked at him, he fell down. We picked him up. As the doctor rushed, we tried whatever we could. I will never forget the look in his three-quarter closed eyes and I held his head with one hand and tried reviving him with whatever I could. His hands clenched, curled onto my finger. There was stillness on his face and those wise eyes were motionlessly radiating wisdom. He never said a word. He did not show pain, only purpose was visible,” he added.
Srijan Pal Singh, in his post, wrote about a conversation he had with Kalam a few days prior to the trip. “Often he would ask me, you are young, decide what you will like to be remembered for? I kept thinking of new impressive answers, till one day I gave up and resorted to tit-for-tat. I asked him back, first you tell me, what will you like to be remembered for? President, Scientist, Writer, Missile man, India 2020, Target 3 billion…. What? I thought I had made the question easier by giving options, but he sprang on me a surprise. “Teacher,” he said.” On revealing the account of the last day of the former president, Singh posted “This is what I will be remembered for…”
On retrospect, Singh writes that ‘Teacher’ is what he always was; standing and lecturing till his last breadth. He ends his post by thanking Kalam for his many contributions to his country. “The man is gone, the mission lives on. Long live Kalam,” posted Singh as a conclusion to his tribute.
Canadian researchers have discovered an overlooked gene that plays a major role in the development of antibodies, which help the immune system recognize and fight viruses including SARS-CoV-2, bacteria and other causes of infectious disease. The gene -- FAM72A -- facilitates production of high-quality antibodies by enabling the effect of an enzyme called AID (for Activation-Induced Deaminase), the researchers showed.
Immunologists have known for two decades that AID is essential to produce antibodies capable of clearing infections, but the full mechanism of its effect has remained unknown. "Our findings answer the long-standing question of how AID does its work," said Alberto Martin, a professor of immunology at the University of Toronto's Temerty Faculty of Medicine. "FAM72A helps AID to promote mutations in antibody genes that are essential for the development of effective antibodies," he added.
Genetic mutations that lead to lasting changes in DNA occur through a process called mutagenesis. | Pixabay
Genetic mutations that lead to lasting changes in DNA occur through a process called mutagenesis. In the context of antibody development, mutagenesis unfolds largely through the AID-driven mechanisms called somatic hypermutation and class switch recombination -- both of which help antibodies gain the diversity and potency they need to counter a wide range of pathogens.
The results published in the journal Nature will help researchers better understand antibody development broadly, but they also have implications for cancer. Uncontrolled mutagenesis in B cells that produce antibodies is linked to B cell lymphoma, and FAM72A is present at very high levels in other cancers such as gastrointestinal, breast, lung, liver and ovarian cancers.
"Our data show that high levels of FAM72A promote mutations in antibody genes, so increased levels of FAM72A could spur cancer development, progression or drug resistance by increasing mutagenesis,a Martin said. Martin's team is now exploring those possibilities. Intriguingly, unlike other mammals, humans have four gene versions of FAM72A and their roles in cancer and antibody production are still unknown. (IANS/ MBI)
Keywords: researchers, cancer, mutagenesis, antibody, development, antibodies, canada, COVID
Mahanadi Coalfields Limited (MCL), a subsidiary of Coal India will set up a 50 megawatt (MW) solar power plant in Odisha's Sambalpur at a total cost of Rs 301.92 crore, moving steadily towards its goal to achieve carbon neutrality by 2024. MCL has placed a turnkey order to set-up a 50 MW solar power plant with a Chennai-based firm M/s Hild Energy Ltd, which will establish this green energy project within a timeline of 10 months, the MCL said in a statement on Saturday.
This solar plant would cater to the captive power requirement of MCL. The Central PSU had successfully set-up a 2MW solar power plant in Sambalpur in 2014. The company said it has pledged a target of installing 182 MW of solar power by 2024 in order to become a net zero energy company, aligning itself to use cleaner forms of energy for coal production.
The company said it has pledged a target of installing 182 MW of solar power by 2024. | Photo by Mariana Proença on Unsplash
This 50 MW solar power project will reduce CO2 emission by 91,020 tonnes per annum and carbon offsets of around 24,824 tonnes per annum, claimed the MCL. MCL is the leading production subsidiary of Coal India, having mining operations in Angul, Jharsuguda and Sundargarh districts of Odisha. Having achieved the highest ever capital expenditure of Rs 2,419 crore in the financial year 2020-21, the company has coal production and dispatch targets of 163 million tonnes and 182 million tonnes, respectively.
MCL was the coal mining company to introduce environment-friendly surface miner technology, which contributes over 95 per cent in coal production. As another environment-friendly initiative, the company has successfully introduced vertical rippers for blast-less over-burden removal in Hingula and Kaniha opencast projects. (IANS/ MBI)
Keywords: solar plant, carbon neutrality, Odisha, Sambalpur, Coal India, subsidiary, Mahanadi Coalfields Limited, solar energy
As the nation celebrated the 114th birth anniversary of his father - renowned poet Harivansh Rai Bachchan - megastar Amitabh Bachchan remembered his dad as he penned a heartfelt note for him. The actor took to his blog where he poured his heart out and also shared an unseen photo with his father. The image in question is from Big B's wedding in 1973, where the two are caught in a sweet moment as they look at each other.
Amitabh Bachchan wrote on his blog,
"My Father , my all .. November 27th his birth in the year 1907 .. Which makes it his 114th Anniversary .. He is in the heavens, with my Mother and they celebrate .. as do we , in thought word and deed .. (sic). But first."
He then posted the picture followed by elaborate paragraphs. The megastar wrote,
"Those rare moments when one would find himself rushing against the winds to prevent the distance between us and to close it down as soon as it can be. The day of my wedding and his expression of fulfilment to not just be in congratulation but instead to be in the face of a belief, a chime, an ultimate season of love and great passion, of the quarries of the fears and conditionings of these deprived gym routines kart ..(sic)". "This could have been unknown for long facilitating years, to give not expected versions and lastly large scale informations of the insides ; but as time passed by, as does now , they explained purposely, the values of education and similarity .. Be in peace and love .. (sic)",
the veteran actor concluded his note. (IANS/ MBI)
Keywords: Amitabh Bachchan, Harivansh Rai Bachchan, actor, blog, birth anniversary, 114th birthday