Friday February 28, 2020

Keto diet May Help You To Fight Against Alzheimer’s Disease, Says Study

Increasing SIRT3 levels via ketone consumption may be a way to protect interneurons and delay the progression of Alzheimer's disease

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Diet
"Ketogenic" is a term for a low-carb diet (like the Atkins diet). The idea is for you to get more calories from protein and fat and less from carbohydrates. Pixabay

Eating low-carb and high-fat diet can help you fight against Alzheimer’s disease, by protect neurons from death during the progression of Alzheimer’s disease, according to new research in mice.

“Ketogenic” is a term for a low-carb diet (like the Atkins diet). The idea is for you to get more calories from protein and fat and less from carbohydrates. You cut back most on the carbs that are easy to digest, like sugar, soda, pastries and white bread.

Early in the development of Alzheimer’s disease, the brain becomes over excited, potentially through the loss of inhibitory, or GABAergic, interneurons that keep other neurons from signaling too much. Because interneurons require more energy compared to other neurons, they may be more susceptible to dying when they encounter the Alzheimer’s disease protein amyloid beta.

Amyloid beta has been shown to damage mitochondria – the metabolic engine for cells – by interfering with SIRT3, a protein that preserves mitochondrial functions and protects neurons. Researchers from the Society for Neuroscience genetically reduced levels of SIRT3 in mouse models of Alzheimer’s disease.

Diet
Eating low-carb and high-fat diet can help you fight against Alzheimer’s disease, by protect neurons from death during the progression of Alzheimer’s disease, according to new research in mice. Pixabay

Mice with low levels of SIRT3 experienced a much higher mortality rate, more violent seizures and increased interneuron death compared to the mice from the standard Alzheimer’s disease model and control mice.

However, the mice with reduced levels of SIRT3 experienced fewer seizures and were less likely to die when they ate a diet rich in ketones, a specific type of fatty acid. The diet also increased levels of SIRT3 in the mice.

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“Increasing SIRT3 levels via ketone consumption may be a way to protect interneurons and delay the progression of Alzheimer’s disease,” report researchers. (IANS)

Next Story

Coronavirus in Iran Leads to Economic Decline

Iranian Economy Faces Setback on Coronavirus Concerns

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Iran coronavirus
Spread of the coronavirus in Iran has pushed that country's currency to lows not seen in almost a year. Pixabay

By Edward Yeranian

Arab media are reporting that the spread of the coronavirus in Iran has pushed that country’s currency to lows not seen in almost a year. Iranian health officials say there are more than 200 confirmed cases in the country, and at least 26 deaths.

Turkey, Armenia, Oman, Bahrain, Kuwait and the United Arab Emirates have all closed land and air borders with Iran in recent days, due to the coronavirus.

As the closures stop the flow of traffic to and from Iran, fears of a deepening economic slump are hitting Iran’s national currency, the riyal.

Arab media say the riyal fell to 158,500 to the dollar on the black market Wednesday, its lowest level in over a year. The riyal’s official peg is 42,000 to the dollar.

Iran coronavirus
As the closures stop the flow of traffic to and from Iran, fears of a deepening economic slump are hitting Iran’s national currency, the riyal. Pixabay

Many economists fear that both Iran’s oil and non-oil exports will be hit by a regional trade slump due to the virus. Religious tourism to Iran’s holy sites will also be affected by border closures and quarantines around public places. Sales during the normally robust pre-Nowrouz new year’s festival are falling.

Despite the downward pressure on Iran’s economy, President Hassan Rouhani told journalists Thursday that the country, until recently, had been thriving.

He said that both industry and agriculture did very well during the past several months. He added that the economy will flourish if Iranians do not let U.S. sanctions or the coronavirus have a psychological impact on their behavior.

Iran coronavirus
Women wear masks to protect themselves against the coronavirus, as they cross a street in Tehran, Iran. VOA

Despite the president’s optimism, state TV showed Iranians in the capital, Tehran, swarming a pharmacy in the pursuit of flu medication and face masks. Panic-buying was also reported at some other businesses.

Former Iranian President Abolhassan Bani Sadr told VOA that “almost everything necessary to fight the virus outbreak is missing in Iran,” and ordinary people “blame their government and U.S. sanctions for the current crisis.”

He added that the Iranian economy depends on trade with its neighbors, so one can just imagine the poverty Iranians face if trade diminishes with partners like Turkey, Iraq, Russia and elsewhere.

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An Iranian member of parliament recently blamed Tehran’s eagerness to come to the rescue of its major trading partner, China, for shortages inside his own country. Iran sent thousands of face masks to China during the initial phase of the coronavirus outbreak, and now faces a severe shortage at home.

“Iranians,” laments former President Bani Sadr, “now have no confidence in the regime or its propaganda, and even less faith that the outside world will come to their rescue.” (VOA)