Sunday December 8, 2019

Lead Intake Promotes Accumulation of Fat in Liver which Can Cause Obesity

And the actual number could be higher as the condition often goes undiagnosed

0
//
Epidemiological studies have shown that this affects nine to 32 per cent of the Indian population. Pixabay

Researchers at the Indian Institute of Technology, Mandi have shown how lead intake promotes accumulation of fat in the liver which can cause obesity.

The scientists have unravelled the mechanism by which lead salt can promote fat accumulation in the liver.

Epidemiological studies have shown that this affects nine to 32 per cent of the Indian population. And the actual number could be higher as the condition often goes undiagnosed.

Non-alcoholic fatty liver disease (NAFLD) is a dangerous epidemic of this generation and is a rapidly growing health problem intimately related to the metabolic group of diseases such as obesity and diabetes, among others.

Lead, Fat, Obesity
Researchers at the Indian Institute of Technology, Mandi have shown how lead intake promotes accumulation of fat in the liver which can cause obesity. Pixabay

It is a conditioAlson wherein there is excessive fat accumulation in the liver.

While obesity has been known to be the leading cause for NAFLD, recent observations have shown that even thin people can be metabolically ‘obese’ and have NAFLD.

Their research work was performed in collaboration with researchers from the Council of Scientific and Industrial Research (CSIR), Indian Institute of Toxicology Research in Lucknow and School of Chemical and Life Sciences in Jamia Hamdard in New Delhi.

This research work has recently been published in a reputed peer-reviewed journal “FEBS Letters”.

Also Read- Graffiti Villages in Taiwan Festoons with Artwork in a Bid to Inject Some Life into Rural Places

Prosenjit Mondal, Assistant Professor, School of Basic Sciences, IIT Mandi, who has uncovered the pathway by which lead promotes NAFLD, said: “While the connection between lead and fatty liver disease has been known for a while, the actual mechanism by which lead worsens this condition has hitherto remained unknown.”

NAFLD and most metabolic group of diseases are often caused by the poor regulation of De novo lipogenesis, a complex process in which carbohydrates circulating in the blood are converted into fat.

The poor regulation of De novo lipogenesis leads to abnormal production of fat, which settles in the liver and other internal organs as visceral fat.

It has been found that the metal lead, which is a serious environmental toxin, can lead to poor regulation of fat formation and deposition in the liver.

Lead, Fat, Obesity
The scientists have unravelled the mechanism by which lead salt can promote fat accumulation in the liver. Pixabay

Lead toxicity is a serious concern in India and the use of lead containing paints, pesticides, packaging and even beer contributes towards high exposure of Indians to this toxic metal and its salts.

Also Read- Elon Musk Plans to Run Tesla Cars on Indian Roads in 2020

Lead salts absorbed by the human body is stored in soft tissues, and autopsy studies have shown that the liver hoards almost 33 per cent of the total lead cruising in the body. (IANS)

Next Story

Parents With Single Child More Likely to Tackle an Obese Kid: Study

Researchers found mothers of singleton children were more likely to be obese themselves

0
Child
Researchers have found that only Child, who researchers refer to as 'singleton,' have less healthy family eating practices, beverage choices, and total Healthy Eating Index 2010 score, coming in lower on three out of the 12 areas measured. Pixabay

Parents with only Child are more likely to tackle an obese kid as children without siblings may be at a higher risk of gaining weight than those who have brothers and sisters, say researchers.

This is because families with multiple children tend to make more healthy eating decisions than families with a single child, the study added.

The study, published in the Journal of Nutrition Education and Behavior, found that this kind of obesity could be seven times more common among youngsters.

“Healthier eating behaviours and patterns may result from household-level changes rather than peer exposure, as peer exposure is also present in away-from-home care,” said study lead author Chelsea L. Kracht from the University of Oklahoma in the US.

According to the researchers, data was self-reported in daily food logs kept by mothers over the course of three days — two weekdays and one weekend day. Teachers kept logs by proxy for any food children ate while at school.

Mothers also completed the Family Nutrition and Physical Activity questionnaire to evaluate typical family eating behaviour like food and beverage choice.

Child
Parents with only Child are more likely to tackle an obese kid as children without siblings may be at a higher risk of gaining weight than those who have brothers and sisters, say researchers. Pixabay

Researchers have found that only-children, who researchers refer to as ‘singletons,’ had less healthy family eating practices, beverage choices, and total Healthy Eating Index 2010 score, coming in lower on three out of the 12 areas measured.

They also had significantly lower total scores across weekdays, weekends, and on average, indicating there are both individual and collective differences in eating patterns between the groups.

Researchers found mothers of singleton children were more likely to be obese themselves. Moreover, maternal BMI had a much stronger connection to child BMI percentile and waist circumference percentile than singleton status.

Maternal BMI did not significantly contribute to overall eating patterns but did contribute to empty calories.

Child
Families with multiple children tend to make more healthy eating decisions than families with a single Child, the study added. Pixabay

The research also found that time spent in away-from-home care like school and daycare was not connected to children’s eating patterns.

“Nutrition professionals must consider the influence of family and siblings to provide appropriate and tailored nutrition education for families of young children,” said Kracht.

ALSO READ: Escalating Consequences of Climate Change Hit Countries Globally

“Efforts to help all children and families establish healthy eating habits and practices must be encouraged,” Kracht added. (IANS)