Wednesday April 8, 2020

Here’s Why Less Consumption of Fruits and Vegetables Can Cause Anxiety

One in nine women had an anxiety disorder compared to one in fifteen men, the study said

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The study, published in the International Journal of Environmental Research and Public Health, found that those who consumed less than three sources of fruits and vegetables daily, there was at least at 24 per cent higher odds of anxiety disorder diagnosis. Pixabay

People who have low fruit and vegetable intakes have a higher likelihood of being diagnosed with an anxiety disorder, say researchers.

The study, published in the International Journal of Environmental Research and Public Health, found that those who consumed less than three sources of fruits and vegetables daily, there was at least at 24 per cent higher odds of anxiety disorder diagnosis.

“This may also partly explain the findings associated with body composition measures. As levels of total body fat increased beyond 36 per cent, the likelihood of anxiety disorder was increased by more than 70 per cent,” said co-author Jose Mora-Almanza, a Mitacs Globalink Intern who worked with the study at Kwantlen Polytechnic University in Canada.

According to the researchers, increased body fat may be linked to greater inflammation. Emerging research suggests that some anxiety disorders can be linked to inflammation.

“Our findings are in keeping with previous research which has also indicated that women are more vulnerable to anxiety disorders than men,” said study co-author Karen Kobayashi.

The study team analysed data from the Canadian Longitudinal Study on Aging which included 26,991 men and women between the ages of 45 and 85. Other factors associated with anxiety disorders among mid-age and older Canadians

In addition to diet and body composition measures, the prevalence of anxiety disorders also differed by gender, marital status, income, immigrant status and several health issues.

One in nine women had an anxiety disorder compared to one in fifteen men, the study said.

Vegetables
People who have low fruit and vegetable intakes have a higher likelihood of being diagnosed with an anxiety disorder, say researchers. Pixabay

The prevalence of anxiety disorders among those who had always been single (13.9 per cent) was much higher than among those who were living with a partner (7.8 per cent).

Approximately one in five respondents with household incomes under $20,000 per year had anxiety disorders, more than double the prevalence of their richer peers.

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“We were not surprised to find that those in poverty had such a high prevalence of anxiety disorders; struggling to afford basics such as food and housing causes relentless stress and is inherently anxiety inducing,” said study co-author Hongmei Tong, Assistant Professor at MacEwan University in Canada. (IANS)

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Here’s Why Autism Spectrum Disorder More Common in Boys

Autism is more commons in boys due to difference in neurons

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Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls, say researchers Pixabay

Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls, say researchers. They found that a single amino acid change in the “NLGN4” gene, which has been linked to autism symptoms, may drive this difference in some cases.

Researchers led by Katherine Roche from National Institutes of Health (NIH) in the US, compared two NLGN4 genes, (one on the X chromosome and one on the Y chromosome), which are important for establishing and maintaining synapses, the communication points between neurons.

Every cell in our body contains two sex chromosomes. Females have two X chromosomes; males have one X and one Y chromosome.

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Until now, it was assumed that the NLGN4X and NLGN4Y genes, which encode proteins that are 97 per cent identical, functioned equally well in neurons.

autism
A single amino acid change in the “NLGN4” gene, which has been linked to autism symptoms, may drive this difference in some cases. Pixabay

But using a variety of advanced technology including biochemistry, molecular biology, and imaging tools, the study, published in the journal Neuron, discovered that the proteins encoded by these genes display different functions.

The NLGN4Y protein is less able to move to the cell surface in brain cells and is therefore unable to assemble and maintain synapses, making it difficult for neurons to send signals to one another. When the researchers fixed the error in cells in a dish, they restored much of its correct function.

“We really need to look at NLGN4X and NLGN4Y more carefully. Mutations in NLGN4X can lead to widespread and potentially very severe effects in brain function, and the role of NLGNY is still unclear,” said study first author Thien A Nguyen.

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The research team found that the problems with NLGN4Y were due to a single amino acid. They also discovered that the region surrounding that amino acid in NLGN4X is sensitive to mutations in the human population.

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In females, when one of the NLGN4X genes has a mutation, the other one can often compensate. However, in males, diseases can occur when there is a mutation in NLGN4X because there is no compensation from NLGN4Y, the researcher said.

“The knowledge about these proteins will help doctors treating patients with mutations in NLGN4X better understand their symptoms,” said Dr Roche. (IANS)