Wednesday March 20, 2019

Lifestyle Habits That Affect Breast Cancer Risk

Changing lifestyle habits, increasing work pressure and stress levels have left modern-day individuals with no time to pay heed to their health and one disease that seems to be emerging because of irregular lifestyle is breast cancer. So make sure you are keeping a check on habits that can lead to this disease.

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Pink Ribbon Campaign
Breast Cancer. Pixabay

Changing lifestyle habits, increasing work pressure and stress levels have left modern-day individuals with no time to pay heed to their health and one disease that seems to be emerging because of irregular lifestyle is breast cancer. So make sure you are keeping a check on habits that can lead to this disease.

Meher Patel, Director at DIVA, Centre for Breast Care (partner with cosmetic brand AVON’s #PayAttention campaign that raises awareness of breast cancer), says:

* Lack of physical activity:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Yoga is also a good physical exercise. Wikimedia

Don’t be proud of being laid back. One of the main reasons is that excess weight causes the body to produce and circulate more estrogen and insulin, hormones that can stimulate cancer growth. It is crucial to keep your body fit at every stage of life continuously using all body parts to sweat out intoxicants that one consumes in this polluted, fast-paced world.

* Alcohol and smoking:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Bottles of Alcohol, Wikimedia

The downside of relaxing in this modern world. The more glasses of drinks you down on the weekend, or packets of cigarettes you puff up, the more you are at risk of breast cancer. Also, for the night owls, it is advisable to find the right balance since irregular patterns of work, long hours and late nights are more likely found to be struck by cancer in the later years of life.

* Long night-shifts at work:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
representational image. Pixabay

After conducting a survey with 300 women-some of whom worked at night, some of whom didn’t the survey found that those who had worked nights for 30 or more years were twice as likely to have developed the disease.

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.

* Hormone replacement therapy (HRT) and contraceptive pills:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Pills, representational Image. Pixabay

Medical improvisations you don’t need! Avoid using the viral popular HRT or contraception tablets to abnormally treat menopausal symptoms and unwanted pregnancy.

* Overweight:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
representational image. pixabay

Start eating healthy and avoid eating out. Putting on weight in adulthood (after the age of 18) with those extra munchies and burgers, or being overweight after menopause can also lead to breast cancer.

Also Read:Effective Treatment to Protect Cancer Patients From Blood Clots

* Other causes:

A few other causes that women tend to overlook is the excess use of deodorants and perfumes, underwired bras, bumping or bruising of breasts, breast implants and abortions that can also be potential threats to breast cancer. (IANS)

Next Story

Common Diabetes Drug May Offer Treatment For Breast Cancer, Says Study

However, neither of the drugs were originally designed to treat cancer

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Cancer
Cancer Ribbon. Pixabay
Repurposing a common diabetes drug as well as another used for treating a group of inherited and acquired disorders may also help in the fight against resistant breast cancers that currently have no targeted therapy, finds a study.
The study, led by the University of Chicago, showed that the two existing drugs named metformin and haemin suppress tumour growth in mice, Xinhua reported.
“This is the first joint use of these two drugs. We think we have elucidated a new mechanism, something basic and fundamental, and found ways to use it,” said Marsha Rosner, Professor at the varsity.
The researchers found that the primary anti-cancer target for haemin is a transcription factor known as BACH1 (BTB and CNC homology1). This protein is often highly expressed in triple negative breast cancers and is required for metastasis.
BACH1 targets mitochondrial metabolism and can suppress a key source of cellular energy. When BACH1 is high, this energy source is shut down, the report said.
However, when cancer cells were treated with haemin, BACH1 was reduced, causing BACH1-depleted cancer cells to change metabolic pathways. This caused cancers that are vulnerable to metformin to suppress mitochondrial respiration.
Diabetes
Representational image. Pixabay
“We found that this novel combination, haemin plus metformin, can suppress tumour growth, and we validated this in mouse tumour models,” explained Jiyoung Lee from the varsity.
The findings can extend beyond breast cancer.
BACH1 expression is enriched not only in triple negative breast cancers, but is also seen in many other cancers including lung, kidney, uterus, prostate and acute myeloid leukemia, the researchers noted.
However, neither of the drugs were originally designed to treat cancer.
Metformin, discovered in 1922 and used clinically since 1957, was developed to treat Type-2 diabetes. It decreases glucose production by the liver and increases insulin sensitivity.
Haemin, marketed as panhematin, was first crystallised from blood in 1853. It is now used to treat defects of haemin synthesis. These defects can cause porphyrias, a group of inherited and acquired disorders. (IANS)